Complex Ketones

Medchemexpress LLC Arecaidine but-2-yny 10mg | 119630-77-2 | 10MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Arecaidine but-2-ynyl ester tosylate (ABET) is a selective mAChR M2 agonist that dose-dependently decreases mean arterial pressure and heart rate in rats Arecaidine but-2-ynyl ester tosylate can be used for cardiovascular disease research[1 [2 Arecaidine but-2-ynyl ester (tosylate) is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

Medchemexpress LLC 17-octadecynoic acid | 34450-18-5 | MFCD00077382 | 98.0% | 280.45 g/mol | C18H32O2 | 10 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

17-Octadecynoic acid is a fatty acid alkyne that functions as a CYP450 ω-hydroxylase inhibitor and a click-chemistry reagent containing an alkyne group. It is used in biochemical assays and in vivo studies to probe CYP450-mediated metabolism and related physiological effects.

• Inhibits CYP450 ω-hydroxylase activity.
• Potent inhibitor of 20-HETE and related metabolite formation.
• Contains alkyne group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
• Validated for in vitro and in vivo experimental applications.
• Provided with high purity for biochemical research.

Medchemexpress LLC 3-thiopheneacetamide, N-[(5-chloro-2-propoxyphenyl)methyl]-N-[2-[4-[(2-propyn-1-ylamino)sulfonyl | 2454246-18-3 | MFCD32263442 | 99.7% | 545.11 g·mol-1 | C27H29ClN2O4S2 | 5 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

YQ128 is a potent, selective, second-generation small-molecule inhibitor of the NLRP3 inflammasome intended for research use. It inhibits NLRP3-mediated IL-1β production (reported IC50 ~0.30 μM), exhibits anti-inflammatory activity, and is reported to cross the blood-brain barrier. The molecule contains an alkyne functional group enabling copper-catalyzed azide-alkyne cycloaddition for conjugation applications.

• Potent NLRP3 inflammasome inhibition (IC50 ~0.30 μM).
• Selectively suppresses IL-1β without inhibiting TNF-α.
• Shows anti-inflammatory activity in cellular models.
• Reported to cross the blood-brain barrier.
• Contains an alkyne group for click-chemistry conjugation.
• Provided as a research reagent with high reported purity.

Medchemexpress LLC YQ128 | 2454246-18-3 | >99.7% | 100 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 μM. It significantly and selectively suppresses the production of IL-1β, but not TNF-α. This compound can cross the blood-brain barrier (BBB) to reach the central nervous system (CNS) and has demonstrated anti-inflammatory activity. YQ128 is also a click chemistry reagent, featuring an Alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. It is intended for research use only.

• Potent and selective second-generation NLRP3 inflammasome inhibitor
• Significantly and selectively suppresses IL-1β production
• Crosses the blood-brain barrier to the central nervous system
• Exhibits anti-inflammatory activity
• Functions as a click chemistry reagent