Uses ATP bioluminescence in microwell based system to detect microbial ATP in Ultra Heat Treated (UTH) and Extended Shelf Life (ESL) dairy and dairy end products
A FASN inhibitor (IC50 213 nM) inhibits the proliferation of PC3 and MV4-11 cells (IC50s 47 and 26 nM respectively) inhibits FASN activity in a 14C-acetate incorporation assay using BT474 cells (IC50 90 nM) reduces tumor growth and increases intratumoral levels of the FASN substrate malonyl-CoA in an MV4-11 mouse xenograft model at 25 and 50 mg/kg inhibits infection of HEK293T-hACE2 cells with SARS-CoV-2-mNG (EC50 17 nM)
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