Oligonucleotides
Sklar Instruments Needle Holder Sklar Microscopy Surgical 1/EA
Needle Holder Sklar Microscopy Surgical 1/EA
Sigma Aldrich Fine Chemicals Biosciences 5-Fluoro-5'-deoxyuridine | 3094-09-5 | MFCD00866530 | 25MG
5-Fluoro-5'-deoxyuridine | Mol Wt: 246.19 | 3094-09-5 | MFCD00866530 | 25MG
Medchemexpress LLC ODN 1018 | 937402-51-2 | DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A) | 1 MG
ODN 1018 (1018 ISS) is a TLR9 agonist and immune modulator. It exhibits adjuvant activity and augments CD8+ T cell responses with LNP-encapsulated OVA peptides. It triggers sustained suppression of allergic airway inflammation and can be used for the research of allergic asthma and systemic lupus erythematosus.
- TLR9 agonist and immune modulator
- Exhibits adjuvant activity
- Augments CD8+ T cell responses with LNP-encapsulated OVA peptides
- Triggers sustained suppression of allergic airway inflammation
- Used for research of allergic asthma
- Used for research of systemic lupus erythematosus
Cayman Chemical Oct4 TrnscrIptIon Factr96
Oct4 is an essential regulator of embryonic stem cell pluripotency and used as a marker for undifferentiated cells. It also plays a role in gene expression, DNA repair and/or replication, signal transduction and tumorigenesis. Cayman’s Oct4 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor-DNA binding activity in nuclear extracts. A 96-well enzyme-linked immunosorbent assay (ELISA) replaces the cumbersome radioactive electrophoretic mobility shift assay (EMSA). A specific double-stranded DNA (dsDNA) sequence containing the Oct4 response element is immobilized onto the wells of a 96-well plate. Oct4, contained in a nuclear extract, binds specifically to the Oct4 response element. Oct4 is detected by the addition of a specific primary antibody directed against Oct4. A secondary antibody conjugated to HRP is added to provide a sensitive colorimetric readout at 450 nm.
Abcam SR-8278, REV-ERBalpha antagonist, 5MG
MW 361.5 Da. REV-ERBα antagonist (EC₅₀ = 470 nM, REV-ERBα transcriptional repression activity). Stimulates the expression of gluconeogenesis genes G6Pase and PEPCK.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical HIston H3CItrulInated R2 1ea
Immunogen: Histone H3 peptide with citrullinations at R2, R8, and R17 • Host: Rabbit • Species Reactivity: (+) Human; other species not tested • Cross Reactivity: (-) Non-citrullinated histone H3 • Applications: ELISA, WB • MW = 16 kDa
New England Biolabs, Inc. NEBNext Multiplex Oligos for Illumina (96 Unique Dual Index Primer Pairs Set 2) – 384 reactions
NEBNext Multiplex Oligos provide adaptors and primers to enable high yield multiplex Illumina library production. Unique Dual Index (UDI) primer pairs enable the identification and mitigation of the impacts of index hopping when using a patterened flow cell. The unique hairpin loop structure of the NEBNext Adaptor minimizes adaptor-dimer formation, and NEBNext index PCR primers enable index incorporation during library amplification. This kit includes 96 pre-mixed unique pairs of i5 and i7 index primers, packaged in a single-use 96-well plate with a pierceable foil seal. Additional NEBNext Multiplex Oligos products are available for different indexing strategies.
New England Biolabs, Inc. NEBNext Multiplex Oligos for Illumina (Dual Index Primers Set 1) – 96 reactions
NEBNext Multiplex Oligos provide adaptors and primers to enable high yield multiplex Illumina library production. The unique hairpin loop structure of the NEBNext Adaptor minimizes adaptor-dimer formation, and NEBNext index PCR primers enable index incorporation during library amplification. This kit includes 8 i5 index primers and 12 i7 index primers for dual indexing. Additional NEBNext Multiplex Oligos products are available for different indexing strategies.
AdipoGen ODN 1826 (Type B) Endotoxin-free (sterile), 1 mg
MW: 6,383g/mol, Synonyms: CpG ODN TLR9 Agonist: B Type (species: rodent). Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic oligonucleotides (ODN) that contain such CpG motifs (CpG ODNs) mimic microbial DNA. The innate immune system of vertebrates has the ability to recognize CpG motifs in microbial DNA via the Toll-like receptor (TLR) 9 if the CpG ODN were free of additional immune stimulatory contaminants often present in synthetic commercial CpG ODN preparations designed for molecular biology applications (i.e. PCR). Given that high quality CpG ODNs were used, a close link has been established between the expression of TLR9 on certain immune cell subsets and the modulation of the immune system by CpG DNA.
Sigma Aldrich Fine Chemicals Biosciences AccuTaqTM LA DNA Polymeras
ACCUTAQTM AccuTaqTM LA DNA Polymeras
Vector Biolabs Tamoxifen inducible Cre (CreERT2-GFP) Adenovirus (Ad-GFP-CreERT2)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA
Invivogen ODN D-SL01 CLASS B CPG OLIGONU
ODN D-SL01 Class B CpG oligonucleotide - Multispecies TLR9 ligand
AdipoGen ODN 2395 (Type C) Endotoxin-free (sterile), 1 mg
MW: 7,068g/mol, Synonyms: CpG ODN: C Type (species: human and rodent). Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic oligonucleotides (ODN) that contain such CpG motifs (CpG ODNs) mimic microbial DNA. The innate immune system of vertebrates has the ability to recognize CpG motifs in microbial DNA via the Toll-like receptor (TLR) 9 if the CpG ODN were free of additional immune stimulatory contaminants often present in synthetic commercial CpG ODN preparations designed for molecular biology applications (i.e. PCR). Given that high quality CpG ODNs were used, a close link has been established between the expression of TLR9 on certain immune cell subsets and the modulation of the immune system by CpG DNA.