Oligonucleotides
Biotium pS2(TFF1/1091), CF568 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
Cayman Chemical 17R 18S-EpETE 100ug
An EPA metabolite and activator of KCa1.1/BK channels; increases the potassium current amplitude by 15-fold in isolated rat cerebral artery VSMCs at 50 nM; has negative chronotropic effects in NRCMs (EC50 = ~1-2 nM) and prevents calcium-induced increases in NRCM spontaneous beating
ABclonal Technology GAPDH Rabbit pAb
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase family, known as a moonlighting protein due to its multiple distinct functions. It catalyzes an important step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate with NAD and inorganic phosphate. The protein also has uracil DNA glycosylase activity in the nucleus and antimicrobial properties against E. coli, P. aeruginosa, and C. albicans. Additionally, similar proteins in mice have been linked to regulating mRNA stability, nitrosylating nuclear proteins, and acting as a transferrin receptor on macrophage surfaces. Many pseudogenes related to this gene exist in the human genome. Alternative splicing generates multiple transcript variants.
Sino Biological Recombinant Human Glypican 4/GPC4 Protein (His & AVI Tag), Avi-tag Biotinylated, HPLC-verified 20 µg
A DNA sequence encoding the Human Glypican 4/GPC4 (O75487-1) (Ala19-Ser529) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
ABclonal Technology Asymmetric DiMethyl-Histone H3-R26 Rabbit pAb
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Medchemexpress LLC PFKM Human HEK293 100ug
PFKM protein is a recombinant human phosphofructokinase (muscle isoform) produced in HEK293 cells and provided as a filtered, stabilized solution for enzymatic and biochemical studies. The preparation is high purity and characterized for activity, and it is supplied in multiple pack sizes with recommended storage at -80°C to preserve function.
- Expressed in HEK293 cells with C-terminal His tag.
- Supplied in buffered formulation with trehalose for stability.
- High purity suitable for biochemical and enzymatic assays.
- Validated specific activity for functional assays.
- Stable when stored at -80°C; avoid repeated freeze-thaw.
Cayman Chemical 8-Iso ProstaglndIn F1 10mg
An isoprostane; a potential autooxidation product of DGLA; induces contractions in isolated neonatal porcine pulmonary arteries at 10 µM
BIOHIPPO AAV-CBh-Cre-WPRE-bGH-polyA
Recombinant adeno associated virus expressing Cre under the CBh promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cusabio Technology LLC LIM and SH3 protein 1
This kit detects LASP1 in human serum plasma tissue homogenates and cell lysates employing a quantitative sandwich ELISA method With a detection range of 25 pg/mL to 1600 pg/mL and a sensitivity of 6 25 pg/mL it enables precise measurement of LASP1 concentrations across diverse biological samples The assay requires 50-100 L of sample per test and can be completed within 1 to 5 hours depending on protocol optimization Absorbance readings are taken at 450 nm ensuring reliable and reproducible results for research applications requiring accurate quantification of LASP1 protein levels in clinical or experimental settings
American Research Products Inc Human GRIN2A ELISA Kit
This Human Glutamate Receptor Ionotropic N-Methyl-D-Aspartate 2A (GRIN2A) ELISA Kit is a precoated Sandwich ELISA assay designed to detect and quantify the target analyte in tissue homogenates cell lysates and other biological fluids This product is for Research Use Only
BIOHIPPO AAV-hSyn-DIO-EGFP-T2A-TK-WPRE-hGH-polyA
Recombinant adeno associated virus expressing TK fused to EGFP under the hSyn promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC Cyclohexaneacetamide, N-(4-methoxyphenyl)- | 340221-20-7 | 99.5% | 247.33 | 1 ML
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH), demonstrating IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH). This compound plays a role in the metabolism of endogenous chemical mediators involved in blood pressure regulation and inflammation. It is supplied as an off-white to light yellow solid, available as a 10 mM * 1 mL solution in DMSO.
- Inhibits soluble epoxide hydrolase (sEH)
- IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH)
- Influences metabolism of endogenous chemical mediators
- Aids in regulation of blood pressure and inflammation
- Appears as an off-white to light yellow solid
Abcam DNA demethylase (total) Activity Quantification Assay Kit.
DNA demethylase (total) Activity Quantification Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Genscript Corporation CD43 His Cynomolgus
CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage CD43 is directly involved in the contact between cells participating in a series of events such as signaling adherence and host parasite interactions The induction of acute myocarditis involves the engagement of CD43 cytoplasmic tripeptide sequence KRR to ezrin-radixin-moiesin cytoskeletal proteins