Oligonucleotides
Meso Scale Discovery R-PLEX Human CCN1 ASYQP
The R-PLEX Human CCN1 Assay is a multiplex immunoassay kit for measuring CCN1 protein in human serum plasma and cell culture supernatants It uses electrochemiluminescence (ECL) on the Meso Scale Discovery (MSD) platform for sensitive detection The kit includes a 96-well plate with capture antibodies detection antibodies calibrators controls diluent and wash buffer Sample incubation is 2 hours with results in 3 5 hours Designed for research use only it requires an MSD instrument The kit offers high sensitivity accuracy and rapid results for quantifying CCN1 levels
VAZYME INTERNATIONAL LLC Vazyme International LLC Library Prep Kit, Universal Plus, Illumina V2
This DNA library preparation kit uses enzyme-based fragmentation for Illumina high-throughput sequencing. It significantly reduces artificial invert chimera reads in FFPE samples, improving SNV and biomarker detection. The kit integrates DNA fragmentation, end repair, and dA-tailing into one step, allowing direct adapter ligation, library amplification, and size selection without additional purification. It can convert 100 pg to 1 μg of template DNA into a library suitable for Illumina platforms.
- Lower false-positive rate for enhanced variant calling.
- Excellent performance with wide template compatibility and high library conversion.
- Integrates DNA fragmentation, end repair, and dA-tailing.
- Direct adapter ligation, library amplification, and size selection.
- Compatible with 100 pg to 1 μg of template DNA.
- Adjustable fragmentation time for desired insert sizes.
Biotium EZH2 / KMT6(EZH2/2536), CF647 conjugate, 0.1mg/mL
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD43 (T-Cell Marker)(rSPN/1094), 1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab
Medchemexpress LLC 4H-Cyclohepta[b]thiophene-3-carboxamide, 2-[(2-bromo-2,2-difluoroacetyl)amino]-5,6,7,8-tetrahydro-N-(2-methylphenyl)- | 2098490-06-1 | C19H19BrF2N2O2S | 5 MG
ANO1-IN-4 (Compound 10bm) is a reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1) with an IC50 of 0.030 μM. It demonstrates good metabolic stability in rat liver microsomes and inhibits spontaneous contraction in mouse isolated ileum.
- Reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A (ANO1)
- IC50 of 0.030 μM
- Good metabolic stability in rat liver microsomes
- Inhibits spontaneous contraction in mouse isolated ileum
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein)(rTFF1/1091), CF568 conjugate, 0.1mg/mL
Recognizes a polypeptide of 6. 5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelih
Sigma Aldrich Fine Chemicals Biosciences 1-(4-Methyl-2-nitroanilino)-4-(3-Pyridylmethyl)Piperazine | CAS 252742-72-6 | 50 GRAMS
STF-1084 | Purity: 98% | Mol Wt: 341.4 | CAS No: 252742-72-6 | MFCD01234567 | 50g
Medchemexpress LLC Seh inhibitor-7 | 340221-20-7 | >99.5% | 247.33 | 50 MG
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. Soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation.
- Inhibitor of soluble epoxide hydrolase (sEH).
- Involved in the regulation of blood pressure.
- Involved in the regulation of inflammation.
Biotium SOX9 / SRY-box 9 (PCRP-SOX9-1E5), CF647 conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are n
Cayman Chemical PalmItIc ACD13CC1 labeled
An internal standard for the quantification of palmitic acid by GC- or LC-MS
Biotium CD43 (T-Cell Marker) (SPN/1766R), 1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundan