Oligonucleotides
ABclonal Technology Non-pAct -CateninS33/S37/T41
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs) AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete Finally this protein binds to the product of the APC gene which is mutated in adenomatous polyposis of the colon Mutations in this gene are a cause of colorectal cancer (CRC) pilomatrixoma (PTR) medulloblastoma (MDB) and ovarian cancer Alternative splicing results in multiple transcript variants
ABclonal Technology Von Hippel Lindau/VHL
This gene encodes a component of a ubiquitination complex The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF) which is a transcription factor that plays a central role in the regulation of gene expression by oxygen In addition to oxygen-related gene expression this protein plays a role in many other cellular processes including cilia formation cytokine signaling regulation of senescence and formation of the extracellular matrix Variants of this gene are associated with von Hippel-Lindau syndrome pheochromocytoma erythrocytosis renal cell carcinoma and cerebellar hemangioblastoma
New England Biolabs, Inc. Monarch HC DNA Cleanup 10 p
The Monarch Spin High-Capacity DNA Cleanup Kit (100 ug) offers higher DNA cleanup capacities and yields compared to our Monarch PCR DNA Cleanup Kit (5 ug) while maintaining the convenient spin column format for silica membrane-based DNA cleanup This high-capacity version efficiently purifies and concentrates up to 100 ug of high-quality double-stranded and single-stranded DNA from enzymatic reactions such as PCR restriction digestion ligation and reverse transcription The kit features precision-engineered spin columns uniquely designed to enable low elution volumes as little as 50 ul resulting in highly concentrated DNA suitable for downstream applications The spin columns are compatible with microcentrifuges centrifuges and vacuum manifolds without additional plastic accessories The optimized buffer system helps ensure efficient DNA binding and purification without the need to adjust pH
New England Biolabs, Inc. Monarch HC DNA Cleanup 10 p
The Monarch Spin High-Capacity DNA Cleanup Kit (100 ug) offers higher DNA cleanup capacities and yields compared to our Monarch PCR DNA Cleanup Kit (5 ug) while maintaining the convenient spin column format for silica membrane-based DNA cleanup This high-capacity version efficiently purifies and concentrates up to 100 ug of high-quality double-stranded and single-stranded DNA from enzymatic reactions such as PCR restriction digestion ligation and reverse transcription The kit features precision-engineered spin columns uniquely designed to enable low elution volumes as little as 50 ul resulting in highly concentrated DNA suitable for downstream applications The spin columns are compatible with microcentrifuges centrifuges and vacuum manifolds without additional plastic accessories The optimized buffer system helps ensure efficient DNA binding and purification without the need to adjust pH
ABclonal Technology Von Hippel Lindau/VHL
This gene encodes a component of a ubiquitination complex The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF) which is a transcription factor that plays a central role in the regulation of gene expression by oxygen In addition to oxygen-related gene expression this protein plays a role in many other cellular processes including cilia formation cytokine signaling regulation of senescence and formation of the extracellular matrix Variants of this gene are associated with von Hippel-Lindau syndrome pheochromocytoma erythrocytosis renal cell carcinoma and cerebellar hemangioblastoma
Bioss KD-Validated FOXO1 Rabbit Reco
Forkhead Box O1 Primary Antibody Unconjugated Public Immunogen Range 450-655/655 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
