Oligonucleotides
Seracare Life Sciences Inc AccuTrak™ HBV DNA Genotype Qualification Panel, 9 Members, Research Use Only, 9 x 1.2 mL
The AccuTrak™ HBV DNA Genotype Qualification Panel is a 9-member validation tool essential for developing and evaluating hepatitis B virus genotype test methods. This panel includes eight HBV DNA positive plasma samples and one negative sample, providing dependable material for optimal assay performance. Its Research Use Only status reinforces its significance for diagnostic manufacturers and clinical laboratories in advancing viral diagnostics.
Medchemexpress LLC PROTAC STING Degrader-1 | 2762552-74-7 | C34H33N7O10 | 5 MG
PROTAC STING Degrader-1 is a PROTAC degrader targeting the STING pathway, demonstrating high anti-inflammatory efficacy with a DC50 of 3.2 μM. It is valuable for studying diseases such as acute kidney injury and inflammatory bowel diseases.
- Targets the STING pathway with a DC50 of 3.2 μM.
- Exhibits high anti-inflammatory efficacy.
- Useful for studying acute kidney injury and inflammatory bowel diseases.
- Downregulates STING pathway signals (IFN-β, IL-6, CXCL10) in THP-1 cells.
- Degrades STING dose- and time-dependently.
- Demonstrates no significant cytotoxicity below 10 μM.
- Alleviates ischemic symptoms and reduces kidney weights in acute kidney injury mouse models.
- Ameliorates severity of DSS-induced colitis in mice.
Meridian Life Science Liquid Stable Flex DNA qPCR, 4ML
Liquid Stable Flex DNA qPCR Mix is a combination of the latest advances in buffer chemistry and PCR enhancers and stabilizers, together with an antibody-mediated hot start polymerase and containing dUTP. Liquid Stable Flex DNA qPCR Mix has been designed to be stable for at least 12 months at ambient temperature. In addition, it has been optimized for highly reproducible and accurate assay, delivering exceptional performance in multiplex assays, even under fast thermal cycling conditions. Liquid Stable Flex DNA qPCR Mix formulation is compatible to applications where reduction of false positives from cross-over contamination is critical.
Meridian Life Science Gly-Free DNA Helicase -HC, 200UL
Glycerol-Free DNA Helicase (HC) Kit is a multi-domain enzyme with both ATPase and helicase activities. It unwinds double-stranded DNA with 3’ to 5’ with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Helicase works in coordination with an accessory protein, methyl-directed mismatch repair (MutL) protein that stimulates the helicase activity. Glycerol-Free DNA Helicase (HC) has been optimized to deliver excellent, stable performance without glycerol, allowing you to deliver reliable results with the added capability for lyophilization. This gives you the flexibility to confidently store mixtures at ambient temperature or produce diagnostic assays that rely on miniaturized reaction components, such as point-of-care assays.
Medchemexpress LLC N-(4-butylphenyl)-5-nitrofuran-2-carboxamide | 346691-38-1 | MFCD00784211 | 99.7% | 288.30 | C15H16N2O4 | 5 MG
STING-IN-2 is a potent, covalent inhibitor of the stimulator of interferon genes (STING) protein used as a research tool to study STING-mediated signaling, innate immune responses, and autoinflammatory disease mechanisms. It inhibits both human and mouse STING and is supplied in small milligram quantities for in vitro and preclinical research.
- Potent covalent inhibition of STING.
- Active against human and mouse STING.
- Useful for studying STING-mediated innate immune signaling.
- Suitable for in vitro and preclinical research applications.
- Characterized and high-purity material for research use.