Oligonucleotides
AdipoGen iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile), AdipoGen Life Sciences. Chemical. MW: 4,887g/mol. In recent years several groups have studied the sequence requirements, specificity, signaling pathways and kinetics of the TLR (Toll-like receptor) 9 suppression by inhibitory oligonucleotide motifs, which led to a class of novel inhibitory oligonucleotide (iODNs), that is independent of the previously thought species preference. Subsequently it has been discovered that telomeric DNA repeats (TTAGGG)n can block immune activation by CpG-ODNs. Short, 11-15 base long oligonucleotides were synthesized that were capable of potently inhibiting CpG-stimulation.
AdipoGen ODN 1585 (Type A) Endotoxin-free (sterile)
ODN 1585 (Type A) Endotoxin-free (sterile), AdipoGen Life Sciences. Chemical. MW: 6,643g/mol. Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic oligonucleotides (ODN) that contain such CpG motifs (CpG ODNs) mimic microbial DNA. The innate immune system of vertebrates has the ability to recognize CpG motifs in microbial DNA via the Toll-like receptor (TLR) 9 if the CpG ODN were free of additional immune stimulatory contaminants often present in synthetic commercial CpG ODN preparations designed for molecular biology applications (i.e. PCR).
Cusabio Technology LLC TAR DNA binding protein
This ELISA kit is designed for the quantitative detection of Human TAR DNA-binding protein 43 (TARDBP/TDP43) in serum plasma cell culture supernates and cerebrospinal fluid (CSF) samples Utilizing a sensitive sandwich assay format the kit demonstrates a broad detection range of 0 312 ng/mL to 20 ng/mL with a low minimum detectable concentration of 0 078 ng/mL ensuring precise measurement across biological matrices The protocol requires 50-100 L of sample per test and delivers results within 1-5 hours through absorbance measurement at 450 nm This kit detects TARDBP with high specificity and reproducibility making it suitable for research applications involving neurological studies biomarker analysis or cellular response monitoring where accurate quantification of TDP-43 protein levels is critical
Revvity Health Sciences Inc NEXTFLEX Unique Dual Index Barcodes (8NT index, 289-384)
NEXTFLEX Unique Dual Index Barcodes (8NT index, 289-384)
Revvity Health Sciences Inc NEXTFLEX Small RNA Sequencing Kit V4
NEXTFLEX Small RNA Sequencing Kit V4
Biotium SOX9 / SRY-box 9(SOX9/2287R), 0.2mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
Revvity Health Sciences Inc NEXTFLEX Unique Dual Index Barcodes (8NT index, 1-8)
NEXTFLEX Unique Dual Index Barcodes (8NT index, 1-8)