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Filtered Search Results
Medchemexpress LLC HY-106024B 200mg Medchemexpress, Alagebrium chloride ALT711 CAS:341028-37-3 Purity:98%
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Medchemexpress,HY-106024B 200mg Alagebrium chloride ALT711 CAS:341028-37-3 Formula:C13H14ClNOS Alagebrium chloride is an advanced glycation end product (AGE) inhibitor. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Clarithromycin >=95% (HPLC) | 81103-11-9 | MFCD00865140 | 100MG
Clarithromycin >=95% (HPLC) | Purity: >=95% (HPLC) | Mol Wt: 747.95 | 81103-11-9 | MFCD00865140 | 100MG
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Medchemexpress LLC Tacedinaline | 112522-64-2 | 99.3% | C15H15N3O2 | 200 MG
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Tacedinaline (N-acetyldinaline) is a potent inhibitor of histone deacetylase (HDAC), demonstrating significant antitumor activity in preclinical models. Its mechanism involves the inhibition of histone deacetylation and cell cycle arrest. This compound exhibits marked synergism when combined with antineoplastic agents like gemcitabine in non-small cell lung cancer cell lines.
- Inhibits histone deacetylase (HDAC 1, 2, and 3)
- Shows broad antitumor activity
- Induces cell cycle arrest
- Synergistic with gemcitabine in non-small cell lung cancer
- Inhibits mitogen-stimulated blood lymphocyte proliferation
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Medchemexpress LLC HY-13205 100mg Medchemexpress, Belnacasan CAS:273404-37-8 Purity:>98%
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Medchemexpress, HY-13205 100mg Belnacasan CAS:273404-37-8 Belnacasan (VX-765) is an orally bioactive prodrug of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16350 5mg Medchemexpress, NKP-1339 CAS:197723-00-5 Purity:>98%
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Medchemexpress, HY-16350 5mg NKP-1339 CAS:197723-00-5 NKP-1339 (IT-139) is the first-in-class ruthenium-based anticancer drug in clinical development against solid cancer with limited side effects. NKP-1339 induces G2/M cell cycle arrest, blockage of DNA synthesis , and induction of apoptosis via the mitochondrial pathway. NKP-1339 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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United States Biological Corporation Erythromycin A 9,11-Imino Ether, 161193-44-8
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Molecular Formula C37H66N2O12, Purity ≥95%, Molecular Weight 730.93, Melting Point >134ºC (dec.), Solubility: Chloroform (slightly), DMSO (Slightly) Methanol (slightly). Erythromycin A 9,11-Imino Ether is an impurity in the synthesis of Erythromycin, a macrolide antibiotic with broad spectrum of antibacterial activity.
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Medchemexpress LLC BX517 | 850717-64-5 | 98.0% | 282.30 | 100 MG
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BX517 is a potent and selective inhibitor of PDK1, demonstrating an IC50 of 6 nM. It effectively blocks the activation of Akt in various tumor cells with submicromolar potency. This compound exhibits significant selectivity, being at least 100-fold more selective against PDK1 compared to a panel of seven other Ser/Thr and Tyr kinases.
- Potent and selective inhibitor of PDK1
- Blocks activation of Akt in tumor cells
- Exhibits submicromolar potency
- Highly selective against other Ser/Thr and Tyr kinases
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Medchemexpress LLC Neomycin (sulfate) (Standard) | 1405-10-3 | 99.9% | 1 G
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Neomycin sulfate is an aminoglycoside antibiotic that functions by irreversibly binding to the nuclear 30S ribosomal subunit, which blocks bacterial protein synthesis. It is utilized in cancer research and has various biochemical inhibitory actions.
- Acts as a phospholipase C (PLC) inhibitor.
- Inhibits the nuclear translocation of angiogenin and its associated cell proliferation and angiogenesis.
- Can inhibit IP3-mediated Ca2+ release.
- Can inhibit MgATP-dependent Ca2+ uptake.
- Can inhibit electrical excitation-evoked skeletal muscle Ca2+ transients.
- Prolonged exposure can deplete gut microbiota in specific mouse models.
- May cause hearing impairment and kidney damage with prolonged exposure.
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Research Products International Corp Amphotericin B, 5 Grams
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Amphotericin B is a polyene antifungal agent known for its efficacy against a broad spectrum of fungi, including yeast and molds. It functions by binding to the fungal cell membrane, forming pores that disrupt membrane integrity. This disruption leads to the leakage of cellular contents, ultimately causing fungal cell death.
Amphotericin B is commonly used to prevent and treat fungal contamination in cell cultures and microbiological experiments. It is added to growth media to maintain aseptic conditions and protect cell lines from fungal overgrowth.
The antifungal activity of Amphotericin B makes it a valuable tool in maintaining the integrity of cell cultures and ensuring reliable experimental results.
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Medchemexpress LLC HY-119459 10mg Medchemexpress, Fluopyram CAS:658066-35-4 Purity:>98%
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Medchemexpress, HY-119459 10mg Fluopyram CAS:658066-35-4 Fluopyram is a succinate dehydrogenase inhibitor fungicide, inhibits the growth of F. virguliforme isolates with mean EC 50 of 3.35 µg/mL [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Biotium LYSOVIEW 680 1000X DMSO 10UL
LYSOVIEW 680 1000X DMSO 10UL
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Medchemexpress LLC Hygromycin A | 6379-56-2 | 511.48 | 25 MG
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Hygromycin A is a *Borrelia burgdorferi*-selective antibiotic that is also a spirochete-specific antibacterial. It contributes to gut health and is utilized in Lyme disease research. In vivo, Hygromycin A selectively eliminates *Borrelia burgdorferi* and positively influences gut microbiota composition, promoting eubiosis.
- Selective antibiotic for *Borrelia burgdorferi*
- Spirochete-specific antibacterial
- Contributes to gut health
- Used for Lyme disease research
- Promotes eubiosis by impacting gut microbiota
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Medchemexpress LLC CARBENICILLIN DISOD 25G
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CARBENICILLIN DISOD 25G
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Medchemexpress LLC PENICILLIN-STREPTOMY 10ML
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PENICILLIN-STREPTOMY 10ML
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Research Products International Corp Penicillin G Potasm Salt 500 G
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Penicillin G potassium salt is a member of the penicillin class of antibiotics and is effective against a variety of gram-positive bacteria. As a narrow-spectrum antibiotic belonging to the beta-lactam class, it inhibits the synthesis of bacterial cell walls. It interferes with the formation of peptidoglycan, a crucial component of the bacterial cell wall. This weakens the cell wall and leads to the eventual rupture of the bacterial cell.
Penicillin G is effective against a wide range of Gram-positive bacteria, including Streptococcus, Staphylococcus, and some other species. However, it is not effective against Gram-negative bacteria due to their different cell wall structure.
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