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Filtered Search Results
Apexbio Technology LLC Clindamycin 18323-44-9 100mg
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Clindamycin (CAS 18323-44-9) is a small-molecule inhibitor targeting the bacterial 50S ribosomal subunit It is designed to disrupt peptide bond formation during protein synthesis thereby inhibiting bacterial proliferation Clindamycin exerts its biological activity primarily through binding to the 50S ribosomal subunit which interrupts peptide elongation and protein assembly In biochemical research Clindamycin demonstrates antimicrobial inhibition with reported IC50 values typically in the low micromolar range depending on bacterial strains and experimental conditions Based on these pharmacological properties Clindamycin holds research potential in microbiological and pharmacological studies for evaluating antimicrobial susceptibility bacterial ribosomal functions and mechanisms of antibiotic resistance
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Medchemexpress LLC Inarigivir ammonium | 2172788-92-8 | MFCD34578292 | 99.0% | 604.53 g/mol | C20H29N8O10PS | 10 MG
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Inarigivir ammonium is a dinucleotide antiviral research compound shown to reduce HBV DNA and RNA in preclinical models. It is supplied as a white to light-yellow solid with high chemical purity for laboratory research applications.
- Dinucleotide antiviral active against hepatitis B virus.
- High purity: 99.04% (HPLC).
- Molecular weight 604.53 g/mol and formula C20H29N8O10PS.
- Solid form suitable for in vitro and preclinical studies.
- Available in small research quantities and DMSO solution formats.
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Medchemexpress LLC Tilmicosin | 108050-54-0 | 98.0% | 100 MG
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Tilmicosin is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. It primarily acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in treating respiratory diseases in livestock such as cattle, sheep, and pigs, and also has immunomodulatory and anti-inflammatory effects.
- Acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis.
- Effective in treating respiratory diseases in livestock.
- Exhibits immunomodulatory effects.
- Exhibits anti-inflammatory effects.
- Has an MIC for 90% of Staphylococcus aureus isolates from bovine udder of 0.78 μg/mL.
- Induces apoptosis of bovine neutrophils.
- Inhibits the expression of COX-2 and iNOS in LPS-treated macrophages.
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Apexbio Technology LLC Merimepodib 198821-22-6 2mg
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Merimepodib (CAS 198821-22-6) is a small-molecule inhibitor targeting inosine monophosphate dehydrogenase (IMPDH) It is designed to inhibit IMPDH thereby blocking the conversion of inosine monophosphate to xanthosine monophosphate and impacting guanine nucleotide biosynthesis Merimepodib exerts its biological activity primarily through noncompetitive inhibition of IMPDH In in vitro studies Merimepodib demonstrates antiproliferative effects suppressing lymphocyte cell growth at approximately 100 nM It also shows antiviral activity with IC50 values of 0 38 M for HBV 0 80 M for HCMV 1 0 M for EMCV and 1 14 M for RSV Based on these pharmacological properties Merimepodib holds research potential in antiviral therapy immunosuppression and transplant rejection models
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Research Products International Corp VALIDAMYCIN A 1GM
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Validamycin A is an antifungal compound. It is a naturally occurring aminocyclitol glycoside and belongs to the class of compounds known as validamycins.
The primary mode of action of validamycin A involves inhibiting trehalase, an enzyme responsible for breaking down trehalose, a type of sugar. Trehalose is important for fungal cell wall integrity and function. By interfering with trehalose metabolism, validamycin A disrupts the fungal cell structure and inhibits its ability to thrive, ultimately leading to the suppression of fungal growth.
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eMolecules 25913-34-2 | Medchem Express | Tinoridine (hydrochloride) | 5mg | 446259951 | HY-111354 | MFCD01680536 | 352.88 | C17H21ClN2O2S
Medchem Express | Pradefovir mesylate | 5mg | 437899204 | HY-112690A | 625095-61-6 | 519.890 | C18H23ClN5O7PS
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Bioworld Carbenicillin Disodium Salt, 5 g
Carbenicillin Disodium Salt Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin. Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.Potency >770 μg/mgHygroscopicUSP gradeMay cause sensitization by inhalation and skin contact.For in vitro lab use only. Not for human use or consumption.
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Medchemexpress LLC Vu0155041 | 1093757-42-6 | 99.10% | C14H15Cl2NO3 | 50 MG
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VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD).
- Potent and selective positive allosteric modulator (PAM) of mGluR4
- EC50s of 798 nM for human mGluR4
- EC50s of 693 nM for rat mGluR4
- Potential for Parkinson's disease research
- Does not affect NMDA receptor currents in striatal medium spiny neurons at 10 μM in vitro
- Reverses catalepsy induced by dopamine D2 receptor antagonist Haloperidol in rats
- Reverses Reserpine-induced akinesia in rats
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Cayman Chemical StreptozotocIn 500mg
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A glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals; specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA, leading to the destruction of beta cells
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Abcam Chloramphenicol ß-D-galactoside, 2MG
MW 485.3 Da. Chloramphenicol precursor that releases chloramphenicol upon enzymatic or chemical hydrolysis. Galactose is linked to the site of action of chloramphenicol via a hydrolysable bond.
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC HY-100381 10mg , Nigericin (sodium salt) CAS:28643-80-3 Purity:>98%
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HY-100381 10mg Nigericin (sodium salt) CAS: 28643-80-3 Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1052147-86-0 | Medchem Express | LP-211 | 5mg | 446260029 | HY-111455 | MFCD22690843 | 466.629 | C30H34N4O
Ambeed | Morpholin-3-one | 5g | 490515397 | A153909 | 109-11-5 | MFCD00631009 | 101.105 | C4H7NO2
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Sigma Aldrich Fine Chemicals Biosciences 5-METHYLTETRAHYDROFOLIC AC 5MG
Sigma-Aldrich Fine Chemicals Biosciences | 5-Methyltetrahydrofolic acid disodium salt | 5 mg | SRE0010-5MG | 68792-52-9 | MFCD00070147 | MW: 503.42
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eMolecules 2096455-90-0 | Medchem Express | Adriforant (hydrochloride) | 5mg | 446270100 | HY-19705B | 371.74 | C13H25Cl3N6
ChemScene | 1-(Benzo[d][13]dioxol-5-yl)cyclobutane-1-carbonitrile | 100mg | 714246701 | CS-0305086 | 405090-49-5 | MFCD11036704 | 201.225 | C12H11NO2
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Medchemexpress LLC Lyn-1604 dihydrochloride | 2310109-38-5 | 99.6% | 657.54 | C33H45Cl4N3O2 | 100 MG
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LYN-1604 dihydrochloride is a research-grade small molecule activator of UNC-51-like kinase 1 (ULK1), used to study autophagy and cell death pathways in preclinical models such as triple negative breast cancer. The compound is supplied as the dihydrochloride salt and is provided with analytical documentation for research use.
- Potent ULK1 activator (EC50 = 18.94 nM).
- High purity suitable for research applications.
- Available as solid and as a DMSO solution for convenient dosing.
- Analytical documentation available, including COA, HNMR, and LCMS.
- Supplied as the dihydrochloride salt for consistent formulation.
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