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Filtered Search Results
Medchemexpress LLC 12-Hydroxydodecanoic acid | 505-95-3 | 98.9% | 50 MG
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12-Hydroxydodecanoic acid is an endogenous metabolite.
- For research use only.
- Not sold to patients.
- Appears as a white to off-white solid.
- Shipping at room temperature in continental US; may vary elsewhere.
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; In solvent at -80°C for 6 months, -20°C for 1 month.
- Solubility in DMSO: 100 mg/mL (462.28 mM) (requires ultrasonic, use newly opened DMSO).
- This product is a controlled substance and may not be for sale in all territories.
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Medchemexpress LLC DGY-06-116 | 2556836-50-9 | 98.6% | 597.11 | 50 MG
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DGY-06-116 is an irreversible, covalent, and selective Src inhibitor with an IC50 of 3 nM. It demonstrates potent antiproliferative effects in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC) cell lines that exhibit SRC activation. This compound effectively induces SRC binding and inhibits SRC signaling in NSCLC cells, and can also inhibit Src for an extended duration in adult C57B6 mice.
- Irreversible covalent, selective Src inhibitor (IC50 of 3 nM)
- Inhibits FGFR1 (IC50 of 8340 nM)
- Exhibits potent antiproliferative effects in NSCLC and TNBC cell lines
- Capable of inducing potent SRC binding and inhibition of SRC signaling in NSCLC cells
- Can inhibit Src for an extended duration in adult C57B6 mice
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Medchemexpress LLC Azido-PEG4-Val-Cit-PAB-OH | 2055024-64-9 | MFCD29918229 | 98.0% | 652.75 | C29H48N8O9 | 50 MG
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Azido-PEG4-Val-Cit-PAB-OH is a cleavable four-unit PEG linker bearing an azide functional group and a protease-sensitive Val-Cit-PAB sequence, used for conjugation via click chemistry and for preparing antibody-drug conjugates or PROTACs.
- cleavable PEG4 linker with azide functionality for click chemistry
- protease-sensitive Val-Cit-PAB sequence for intracellular payload release
- solid, white to off-white appearance suitable for storage as a powder
- high purity suitable for research use
- stable when stored at recommended low temperatures
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Medchemexpress LLC Bemnifosbuvir | 1998705-64-8 | 99.0% | 581.53 | 50 MG
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Bemnifosbuvir (AT-511) is a potent and orally active inhibitor of HCV viral replication. It is highly effective in controlling SARS-CoV-2 (COVID-19) infection in vitro with an EC90 of 0.47 μM. Bemnifosbuvir exhibits pangenotypic antiviral activity.
- Highly effective in controlling SARS-CoV-2 (COVID-19) infection in vitro
- Exhibits pangenotypic antiviral activity
- Inhibits HCV genotype 1a (EC50: 12.8 nM)
- Inhibits HCV GT1b (EC50: 12.5 nM)
- Inhibits HCV GT2a (EC50: 9.2 nM)
- Inhibits HCV GT3a (EC50: 10.3 nM)
- Inhibits HCV GT4a (EC50: 14.7 nM)
- Inhibits HCV GT5a (EC50: 28.5 nM)
- Preferentially delivers high levels of AT-9010 to the liver in vivo
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Medchemexpress LLC Erythromycin estolate | 3521-62-8 | 10 MM * 1 ML
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Erythromycin estolate is a macrolide antibiotic and a derivative of Erythromycin used to treat a wide variety of bacterial infections. It is intended for research use only and not sold to patients. This compound can cause liver injury, primarily cholestatic hepatitis, due to its inhibitory effect on bile acid transport.
- Purity: 98.0%
- Molecular weight: 1056.39
- Formula: C52H97NO18S
- Functions as a macrolide antibiotic
- Used to treat bacterial infections
- Inhibits various flaviviruses including Zika, dengue, and yellow fever
- Inactivates viral particles by destroying viral membrane integrity
- Inhibits human BSEP with an IC50 of 4.1 μM
- Available as a solid, white to off-white in color
- Storage conditions: 4°C in sealed storage, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC β,β-Dimethylacrylalkannin (Arnebin 1) | 34539-65-6 | 5 MG
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β,β-Dimethylacrylalkannin (Arnebin 1) | 34539-65-6 | 5 MG
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Sigma Aldrich Fine Chemicals Biosciences Colistin sodium methanesulfonate | 8068-28-8 | MFCD00130824 | 10mu
Colistin sodium methanesulfonate | 8068-28-8 | MFCD00130824 | 10mu
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AdipoGen Daptomycin
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Chemical. CAS 103060-53-3. Formula C72H101N17O26. MW 1620.7. Daptomycin, a naturally occurring cyclic lipopeptide, is a calcium-dependent antibiotic. It exhibits potent bacteriocidal activity against most Gram-positive bacteria in vitro and in vivo, including antibiotic-resistant strains such as MRSA and VRE. Daptomycin disrupts the bacterial plasma membrane function, which results in membrane depolarization consequently leading to inhibition of protein, DNA and RNA synthesis, essential for cell division and cell wall synthesis.
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Boston Bioproducts Inc Gentamicin (20 mg/ml, dH2O) - 100ml
Gentamicin (20 mg/ml dH2O) - 100ml (For Research Use and Further Manufacturing Only)
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Medchemexpress LLC HY-B0486 50mg , Lonidamine DICA;Diclondazolic Acid;AF1890 CAS:50264-69-2 Purity:98%
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Medchemexpress, HY-B0486 50mg Lonidamine DICA;Diclondazolic Acid;AF1890 CAS:50264-69-2 Formula:C15H10Cl2N2O2 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15260A 100mg , XL413 (hydrochloride) CAS:1169562-71-3 Purity:98%
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Medchemexpress, HY-15260A 100mg XL413 (hydrochloride) CAS:1169562-71-3 Formula:C14H13Cl2N3O2 IC50: 3.4 nM (Cdc7), 42 nM (PIM1), 215 nM (CK2) EC50: 118 nM (pMCM) Purity:98% XL413 hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7 , with an IC 50 of 3.4 nM, and also shows potent effect with IC 50 s of 215, 42 nM on CK2, PIM1, respectively, and an EC 50 of 118 nM on pMCM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16752 50mg , Relebactam MK-7655 CAS:1174018-99-5 Purity:98%
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Medchemexpress, HY-16752 50mg Relebactam MK-7655 CAS:1174018-99-5 Formula:C12H20N4O6S Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15718A 100mg , Istaroxime (hydrochloride) PST2744 (hydrochloride) CAS:374559-48-5 Purity:98%
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Medchemexpress, HY-15718A 100mg Istaroxime (hydrochloride) PST2744 (hydrochloride) CAS:374559-48-5 Formula:C21H33ClN2O3 IC50: 0.11 μM (Na + ,K + -ATPase) Purity:98% Istaroxime hydrochloride is a potent inhibitor of Na + ,K + -ATPase with IC 50 of 0.11 μM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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ADOOQ BIOSCIENCE LLC FT671 USP7 INHIBITOR 1MG
NC2591331 FT671 USP7 INHIBITOR 1MG
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Medchemexpress LLC HY-15463 5g , Imatinib STI571 CAS:152459-95-5 Purity:98%
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Medchemexpress, HY-15463 5g Imatinib STI571 CAS:152459-95-5 Formula:C29H31N7O IC50: ~100 nM (c-Kit, Bcr-Abl, and PDGFR) Purity:98% Imatinib is a known inhibitor of the c-Kit , Bcr-Abl , and PDGFR tyrosine kinases, inhibits the SLF-dependent activation of c-Kit wt kinase with IC 50 of ~100 nM, which is similar to the concentration requires for inhibition of Bcr-Abl and PDGFR. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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