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Filtered Search Results
MEDCHEMEXPRESS LLC R-GNE-140 5MG
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501871753 R-GNE-140 5MG
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Biotium LYSOVIEW 594 1000X DMSO 10UL
LYSOVIEW 594 1000X DMSO 10UL
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Biotium LYSOVIEW 640 1000X DMSO 10UL
LYSOVIEW 640 1000X DMSO 10UL
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Alkali Scientific Ampicillin, Sodium Salt, 5 G
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Ampicillin Sodium Salt is a broad spectrum beta lactam antibiotic used extensively in microbiology and molecular biology laboratories. It works by inhibiting bacterial cell wall synthesis, resulting in effective suppression of susceptible organisms. This product is supplied as a high purity powder that allows accurate preparation of stock solutions for culture media and experimental use. It is commonly used for selecting transformed cells that carry ampicillin resistance genes, as well as for general antibacterial research. The consistent formulation ensures reliable performance in laboratory workflows that require controlled bacterial inhibition and reproducible results.
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Apexbio Technology LLC Cyproheptadine hydrochloride 969-33-5 50mg
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Cyproheptadine hydrochloride (969-33-5) is a small-molecule antagonist targeting serotonin (5-HT) and histamine receptors especially the 5-HT2A subtype It is designed to competitively antagonize these receptors thereby regulating serotonergic and histaminergic signaling pathways Cyproheptadine hydrochloride exerts its biological activity primarily through serotonin and histamine receptor antagonism and also exhibits antimuscarinic effects In in vitro studies cyproheptadine hydrochloride demonstrates inhibition of serotonin-enhanced platelet aggregation induced by ADP with an IC50 value commonly reported near 20 nM toward human 5-HT2A receptors Based on these pharmacological properties cyproheptadine hydrochloride holds research potential in antithrombotic studies post-gastrectomy dumping syndrome migraine pruritic dermatoses anorexia and pituitary-dependent Cushing s syndrome
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eMolecules 147025-53-4 | Medchem Express | Talsaclidine | 1mg | 482204340 | HY-128855 | 165.236 | C10H15NO
Ambeed | (3aR3bS6S6aR7aR)-6-Hydroxy-22-dimethyltetrahydrofuro[2345]furo[23-d][13]dioxol-5(3aH)-one | 25g | 525197511 | A365252 | 20513-98-8 | MFCD01863407 | 216.189 | C9H12O6
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Selleck Chemical LLC Sulbactam S1958-200mg
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Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0 8 M
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Selleck Chemical LLC Azithromycin S1835-200mg
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Azithromycin is an antibiotic by inhibiting protein synthesis used for the treatment of bacterial infections
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Apexbio Technology LLC YM 58483,10mg CAS# 223499-30-7
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YM 58483, also known as BTP2, is a SOCE blocker. SOCE has been found in macrophages, basophils, dendritic cells, and mast cells as well as T cells. The SOCE-related channels include the Ca2+ release-activated Ca2+ (CRAC) channel which is a highly Ca2+-selective channel, and the non-selective, Ca2+-permeable transient receptor potential (TRP) channels, which regulate the activation of non-excitable cells such as lymphocytes. YM 58483 has been reported to inhibit cytokine production and proliferation in T cells, and may serve as a potential medicinal candidate for treatment of bronchial asthma. Other sizes are also available. Please inqury us for quote.
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Medchemexpress LLC Loratadine-d5 | 1398065-63-8 | 99.96% | 387.91 | 5 MG
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Loratadine-d5 is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. It has anti-dengue-virus (DENV) activity and can inhibit immunologic release of inflammatory mediators. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Selective inverse peripheral histamine H1-receptor agonist.
- Has anti-dengue-virus (DENV) activity.
- Can inhibit immunologic release of inflammatory mediators.
- Can be used as a tracer or an internal standard for quantitative analysis.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Vancomycin (hydrochloride) | 1404-93-9 | 99.47% | 1450 Da | 250 MG
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Vancomycin hydrochloride is an antibiotic used for treating bacterial infections. It functions by inhibiting the second stage of cell wall synthesis in susceptible bacteria. Additionally, vancomycin modifies the cell membrane's permeability and selectively suppresses ribonucleic acid synthesis.
- Inhibits bacterial cell wall synthesis.
- Alters cell membrane permeability.
- Selectively inhibits ribonucleic acid synthesis.
- Active against many Gram-positive bacteria, including *Staphylococcus aureus* and enterococci.
- Glycopeptide compound.
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Apexbio Technology LLC SEMAGACESTAT LY450139 5MG
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502240479 SEMAGACESTAT LY450139 5MG
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Apexbio Technology LLC Palifosfamide,5mg CAS# 31645-39-3
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Palifosfamide is the active moiety of ifosfamide (IFA) [1].IFA is alkylating agents which are active against a variety of pediatric sarcomas such as rhabdomyosarcoma (RMS), Ewing’s sarcoma (ES), osteosarcoma (OS) and other undifferentiated soft tissue sarcomas [1].In human OS cell lines SaOS-2, OS229 and OS230, Palifosfamide lysine has broad activity with IC50 ranging from 2.25 to 6.75 μM. While OS222 had the IC50 of 31.5 μM [1].In CB17 female SCID mice, palifosfamide lysine (100 mg/kg) administered intravenously for three consecutive days, the mean weight loss was less than 15% and complete recovery to baseline within 4 weeks of treatment. Other sizes are also available. Please inqury us for quote.
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MEDCHEMEXPRESS LLC TIGECYCLINE 10MG
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501874045 TIGECYCLINE 10MG
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Apexbio Technology LLC FR 180204 865362-74-9 10mg
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FR 180204 (CAS 865362-74-9) is a small-molecule inhibitor targeting extracellular signal-regulated kinase (ERK) specifically ERK1 and ERK2 It modulates ERK activity thereby regulating MAP kinase signaling pathways FR 180204 exerts its biological activity primarily through ATP-competitive inhibition of ERK1 and ERK2 In in vitro studies FR 180204 demonstrates selective inhibition of ERK1 and ERK2 with IC50 values of 0 31 M and 0 14 M respectively and limited inhibition of related kinases In cell-based assays using Mv1Lu cells it inhibits TGF -induced AP-1 transcriptional activation with an IC50 of approximately 3 1 M Based on these pharmacological properties FR 180204 holds research potential in elucidating ERK-mediated signaling and transcriptional regulation in biomedical studies
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