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Filtered Search Results
Medchemexpress LLC HY-15287 5mg Medchemexpress, Nelfinavir CAS:159989-64-7 Purity:>98%
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Medchemexpress, HY-15287 5mg Nelfinavir CAS:159989-64-7 Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) and antiviral agent for the treatment of HIV infection. Nelfinavir is a broad-spectrum, anticancer agent [1] [2] [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-B0180A 200mg Medchemexpress, Imiquimod (hydrochloride) CAS:99011-78-6 Purity:>98%
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Medchemexpress, HY-B0180A 200mg Imiquimod (hydrochloride) CAS:99011-78-6 Imiquimod hydrochloride (R 837 hydrochloride) is a selective toll like receptor 7 (TLR7) agonist acting as an immune response modifier. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID 19. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Potassium oxonate | 2207-75-2 | 99.9% | 195.17 | 500 MG
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Potassium oxonate (Potassium azaorotate) is a uricase inhibitor primarily used in research to inhibit the phosphorylation of 5-FU and for creating hyperuricemia animal models. This selective competitive inhibitor blocks hepatic uricase and is metabolized in the gastrointestinal tract, distributing primarily in small intestine cells where it is converted to cyanuric acid.
- Inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
- Utilized in animal modeling to create hyperuricemia models.
- Functions as a selective competitive uricase inhibitor.
- Blocks the action of hepatic uricase.
- After metabolism, primarily distributes within the cells of the small intestine.
- Converted to cyanuric acid in the gastrointestinal tract through two pathways.
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eMolecules 30544-47-9 | Medchem Express | Etofenamate | 100mg | 446268239 | HY-17361 | MFCD00242806 | 369.34 | C18H18F3NO4
Ambeed | 2-(Methylamino)benzamide | 250mg | 592282782 | A323524 | 7505-81-9 | MFCD00025469 | 150.181 | C8H10N2O
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MOLTOX Molecular Toxicology Inc Mitomycin C, 5 ug/vial, 5 vials/pack, Store in Refrigerator
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For use in Ames test with TA102 tester strain. Dose 0.5 µg/plate. Reconstitute with organic solvents such as DMSO or sterile dH2O as applicable. Direct acting mutagens do not require the use of S9 metabolic activation to cause mutagenicity. CONTROLCHEM™ chemicals are obtained from major suppliers of research chemicals and are employed without further characterization or purification. Packaged quantities are precise within 1%. Please Note: CONTROLCHEM™ chemicals are known mutagens/carcinogens/toxins and are sold only to those experienced in the safe handling and disposal of hazardous materials. Consult your Institutional Safety Officer before ordering.
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Research Products International Corp Chlortetracycline Hydrochloride, 5 Grams
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Chlortetracycline Hydrochloride is a tetracycline antibiotic. Chlortetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. The interference disrupts the translation process and inhibits bacterial growth.
This antibiotic offers a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. It also forms complexes with calcium, magnesium, aluminum, and iron, leading to reduced absorption.
Additionally, it is useful to study bacterial susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.
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eMolecules 53123-88-9 | Sirolimus | Advanced ChemBlocks - In Stock914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g...
Sirolimus | Advanced ChemBlocks - In Stock | 53123-88-9914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g | 381426230
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Medchemexpress LLC LEQ506 | 1204975-42-7 | 98.9% | 432.56 | 100 MG
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LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50 values of 2 nM in human and 4 nM in mouse. It inhibits Hedgehog (Hh) signaling in a human cell line (HEPM) by decreasing Gli mRNA, with an IC50 approximately 6-fold lower than that of Compound 2. At 1%, LEQ506 achieves 80% to 90% inhibition for Gli1 and 60% to 70% for Ptch1.
- Inhibits smoothened (Smo)
- Has IC50 values of 2 nM in human and 4 nM in mouse
- Inhibits Hedgehog (Hh) signaling
- Decreases Gli1 mRNA by 70% to 80%
- Preferentially inhibits Gli1 over Ptch1 mRNA
- Is an efficacious compound
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eMolecules 2320274-78-8 | Medchem Express | (RS)-Butyryltimolol | 5mg | 446257606 | HY-102032A | 386.51 | C17H30N4O4S
Ambeed | 4-Bromo-2-hydroxybenzamide | 250mg | 649783284 | A866671 | 5428-40-0 | MFCD07780674 | 216.034 | C7H6BrNO2
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Sigma Aldrich Fine Chemicals Biosciences Chlortetracycline hydrochloride British Pharmacopoeia (BP) Reference Standard | 64-72-2 | MFCD00082440 |
Chlortetracycline hydrochloride British Pharmacopoeia (BP) Reference Standard | Mol Wt: 515.34 | 64-72-2 | MFCD00082440 |
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Medchemexpress LLC C-021 dihydrochloride | 1784252-84-1 | 99.9% | 540.57 g/mol | C27H43Cl2N5O2 | 10 MG
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C-021 dihydrochloride is the dihydrochloride salt of a small-molecule antagonist of the CC chemokine receptor 4 (CCR4) provided for laboratory research. It inhibits CCR4-mediated chemotaxis in human and mouse systems and has been characterized in functional and binding assays.
- Potent CC chemokine receptor 4 (CCR4) antagonist with reported low-nanomolar activity.
- High chemical purity (reported ~99.9%).
- Supplied as a solid; common pack sizes include 10 mg.
- Molecular formula C27H43Cl2N5O2; molecular weight 540.57 g/mol.
- Intended for research and analytical applications only.
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eMolecules 17302-61-3 | Medchem Express | Poloxime | 5mg | 446271528 | HY-77195 | MFCD22572808 | 179.219 | C10H13NO2
Ambeed | 3-Bromothieno[32-b]thiophene | 1g | 570573858 | A182276 | 25121-83-9 | MFCD10000952 | 219.110 | C6H3BrS2
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Sigma Aldrich Fine Chemicals Biosciences Cidofovir Related Compound B United States Pharmacopeia (USP) Reference Standard | 120362-35-8 (free base) | 15MG
Cidofovir Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 371.75 | 120362-35-8 (free base) | 15MG
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Sigma Aldrich Fine Chemicals Biosciences Anisomycin, Ready Made Solution from Streptomyces griseolus 10 mg/mL in DMSO, 0.2 mum filtered | 22862-76-6 | 0.5ML
Anisomycin, Ready Made Solution from Streptomyces griseolus 10 mg/mL in DMSO, 0.2 mum filtered | Mol Wt: 265.3 | 22862-76-6 | 0.5ML
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Medchemexpress LLC FB23 | 2243736-35-6 | 98.9% | 377.22 | 50 MG
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FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. It directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
- Potent and selective FTO demethylase inhibitor
- IC50 of 60 nM against FTO
- Directly binds to FTO
- Selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity
- Inhibits proliferation of acute myeloid leukemia (AML) cells (e.g., NB4 and MONOMAC6)
- Suppresses MYC and E2F targets
- Activates apoptosis and p53 pathways
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