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Filtered Search Results
eMolecules Paquinimod | 248282-01-1 | MFCD18633277 | 50mg
Ambeed | Paquinimod | 50mg | 552740551 | A525721 | | 248282-01-1 | MFCD18633277 | 350.418 | C21H22N2O3
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Medchemexpress LLC Duvelisib 50Mg | HY-17044-50MG
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Duvelisib 50Mg
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Medchemexpress LLC VU0463271 | 1391737-01-1 | 99.8% | 382.50 | 10 MG
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VU0463271 is a selective and potent KCC2 antagonist. It demonstrates high selectivity over NKCC1 and no activity against a broad panel of GPCRs, ion channels, and transporters. In vitro, it is rapidly cleared. In vivo studies in rats show it is a moderate-to-high clearance compound.
- IC50 of 61 nM for KCC2.
- >100-fold selectivity over NKCC1.
- No activity against GPCRs, ion channels, and transporters.
- Rapidly cleared in vitro.
- Significantly increased firing rates in Drosophila CNS.
- Moderate-to-high clearance (CL=57 mL/min/kg) in rats after intravenous administration.
- Low volume of distribution at steady state (Vss 0.4 L/kg) in rats.
- Relatively short t1/2 (9 min) in rats.
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Medchemexpress LLC Mrs-3777 hemioxalate | 1186195-57-2 | 96.3% | 399.40 | 500 MG
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MRS-3777 hemioxalate is a selective adenosine A3 receptor antagonist.
- Selective adenosine A3 receptor antagonist
- For research use only
- Target: Adenosine A3 receptor
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Medchemexpress LLC Lumefantrine-d9 (Benflumetol-d9) | 2477594-24-2 | 97.0% | 5 MG
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Lumefantrine-d9 is a deuterium-labeled version of Lumefantrine, an antimalarial drug. It is commonly used in combination with Artemether, forming a combination therapy (AL) that serves as a first- and second-line antimalarial treatment.
- Can be utilized as a tracer in research applications.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Stable isotope used for quantitation during drug development processes, with potential to influence pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Oxolinic acid | 14698-29-4 | 98.97% | 500 MG
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Oxolinic acid is an antibiotic effective against both Gram-negative and Gram-positive bacteria. It is used in research for acute and chronic urinary tract infections. It functions as a DNA/RNA synthesis inhibitor and also acts as a dopamine uptake inhibitor, stimulating locomotor effects in mice.
- Antibiotic active against Gram-negative and Gram-positive bacteria.
- Used for research in acute and chronic urinary tract infections.
- Functions as a DNA/RNA synthesis inhibitor.
- Acts as a dopamine uptake inhibitor.
- Stimulates locomotor effects in mice.
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Medchemexpress LLC Erythromycin Ethylsuccinate | 1264-62-6 | MFCD00084692 | 79.0% | 500 MG
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Erythromycin Ethylsuccinate is an antibiotic used for treating various bacterial infections. Its antimicrobial spectrum is similar to or slightly broader than that of penicillin. It also exhibits antiviral activity against HIV-1.
- Antibiotic useful for the treatment of a number of bacterial infections.
- Antimicrobial spectrum similar to or slightly wider than that of penicillin.
- Antiviral activity against HIV-1.
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Medchemexpress LLC Paromomycin sulfate | 1263-89-4 | 99.9% | 1 ML
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Paromomycin sulfate is a neomycin derivative, functioning as a broad-spectrum aminoglycoside antibiotic with both amebicidal and bactericidal effects. It primarily works by prematurely terminating mRNA translation and inhibiting protein synthesis through specific binding to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. This compound is utilized in the research of various bacterial and parasitic infections.
- Broad-spectrum aminoglycoside antibiotic
- Exhibits amebicidal and bactericidal effects
- Inhibits protein synthesis by targeting bacterial 30S ribosomes
- Useful in research for bacterial and parasitic infections
- Demonstrates reduction in intracellular parasitic forms in cell cultures
- Shown to reduce oocysts in vivo models
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Apexbio Technology LLC Chloramphenicol(Synonyms: Chloromycetin, Levomycetin, Chlornitromycin, Fenicol, Amphicol, Kemicetine), 10mM (in 1mL DMSO), CAS: 56-75-7.
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Chloramphenicol (CAS 56-75-7) is a small molecule antibiotic commonly utilized in molecular biology research It exerts anti-microbial activity by specifically binding to the bacterial 50S ribosomal subunit thereby inhibiting the peptidyl transferase reaction and subsequently blocking protein synthesis At elevated concentrations chloramphenicol may also impede DNA synthesis in eukaryotic cells In plasmid selection assays typical effective concentrations are approximately 25 g/ml for stringent plasmids and 170 g/ml for relaxed plasmids For laboratory storage chloramphenicol solutions are maintained at 4 C
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Apexbio Technology LLC Ampicillin sodium(Synonyms: Ampicillin sodium salt, Sodium ampicillin, D-(-)-α-Aminobenzylpenicillin sodium salt), 10mM (in 1mL H2O), CAS: 69-52-3.
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Ampicillin sodium (CAS 69-52-3) is a -lactam antibiotic that exerts antibacterial activity by competitively inhibiting bacterial transpeptidase enzymes Transpeptidases catalyze the critical final steps of bacterial cell wall biosynthesis their inhibition disrupts cell-wall integrity leading to bacterial cell lysis In assays using E coli 146 cells ampicillin sodium demonstrates an IC50 value of 1 8 g/ml against transpeptidase and an MIC value of 3 1 g/ml Research studies utilize ampicillin sodium to evaluate antibacterial efficacy in vitro and in animal infection models
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Medchemexpress LLC Latanoprost | 130209-82-4 | 216074 | >99.85% | 100 MG
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Latanoprost is a prostaglandin F2α analogue primarily utilized in glaucoma research. This compound is capable of penetrating the cornea, where it is subsequently hydrolyzed by esterase into its active form, latanoprost acid. The acid then functions as an F-prostaglandin (FP) receptor agonist, efficiently reducing intraocular pressure by facilitating an increased outflow of aqueous humor via the uvea.
- Prostaglandin F2α analogue for research
- Passes through the cornea and is hydrolyzed to active acid form
- Acts as an F-prostaglandin (FP) receptor agonist
- Effectively lowers intraocular pressure (IOP)
- Increases aqueous humor outflow through the uvea
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Medchemexpress LLC Neomycin sulfate (Standard) | 1405-10-3 | 99.9% | 250 MG
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Neomycin sulfate (Standard) is an analytical standard for research applications. This aminoglycoside antibiotic functions by irreversibly binding to the bacterial 30S ribosomal subunit, blocking protein synthesis. It also acts as a phospholipase C (PLC) inhibitor and inhibits nuclear translocation of angiogenin, along with angiogenin-induced cell proliferation and angiogenesis.
- Analytical standard for research and analytical applications
- Aminoglycoside antibiotic
- Inhibits bacterial protein synthesis by binding to 30S ribosomal subunit
- Functions as a phospholipase C (PLC) inhibitor
- Potently inhibits nuclear translocation of angiogenin
- Inhibits angiogenin-induced cell proliferation and angiogenesis
- Used in qualitative, quantitative, and methodological research experiments (HPLC, GC, MS)
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Medchemexpress LLC Tebipenem pivoxil | 161715-24-8 | 99.7% | 50 MG
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Tebipenem pivoxil (L084) is an orally active antibiotic that effectively targets various pathogenic bacteria by inhibiting cell wall synthesis through binding to penicillin-binding protein (PBP). It is intended for research use only.
- Orally active antibiotic
- Effective against various pathogenic bacteria
- Inhibits cell wall synthesis
- Binds to penicillin-binding protein (PBP)
- Shows excellent antibacterial activity (0-128 μg/mL; 18-24 h)
- Inhibits Gram-positive and Gram-negative bacteria with MIC50s below 64 μg/mL
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eMolecules Aminohippurate sodium | 94-16-6 | MFCD00044689 | 100mg
Ambeed | Aminohippurate sodium | 100mg | 506391504 | A639297 | | 94-16-6 | MFCD00044689 | 216.172 | C9H9N2NaO3
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Medchemexpress LLC HY-N2149 100mg , Tomatidine CAS:77-59-8 Purity:98%
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Medchemexpress, HY-N2149 100mg Tomatidine CAS:77-59-8 Formula:C27H45NO2 NF-κB JNK Purity:98% Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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