Cell Culture Growth Factors and Hormones
Genscript Corporation FGFR3 beta IIIcBiotin His
Four distinct genes encoding closely related FGF receptors FGF R1-4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation differentiation and apoptosis Plays an essential role in the regulation of chondrocyte differentiation proliferation and apoptosis and is required for normal skeleton development Regulates both osteogenesis and postnatal bone mineralization by osteoblasts
Genscript Corporation GH HumanCHO-expressed
Growth Hormone (GH) is a member of the somatotropin/prolactin family which play an important role in growth control The human GH cDNA encodes a 217 amino acid (aa) and the first 26 aa is a signal peptide By alternative splicing at least four isoforms of GH have been identified The major role of GH in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1 GH stimulates both the differentiation and proliferation of myoblasts and also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Meso Scale Discovery U-PLEX Mouse TGF-B3 ASY
The Meso Scale Discovery U-PLEX Mouse TGF-beta3 Assay Kit is an electrochemiluminescent immunoassay for quantifying mouse TGF-beta3 in serum plasma cell culture supernatants and other samples It uses the QuickPlex SQ 120 instrument and multi-array technology for sensitive detection in 25 L samples The kit includes a 96-well plate with capture antibodies detection antibodies calibrators diluent wash buffer read buffer and seals Sensitivity is 1 3 pg/mL with an upper quantification limit of 10 000 pg/mL
Genscript Corporation PDGF R beta/CD140bBiotin Hi
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains The PDGF-AA PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities Where as PDGF R alpha binds all three PDGF isoforms with high affinity PDGF R beta binds PDGF-BB only with high-affinity PDGF R plays an essential role in blood vessel development by promoting proliferation migration and recruitment of pericytes and smooth muscle cells to endothelial cells Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites
Advanced Biomatrix PhotoGel 50% DOM Methacrylated Gelatin with Irgacure Kit
PhotoGel is lyophilized, sterile, medium degree of methacrylation (~50%) methacrylated gelatin. PhotoGel provides 3D gelatin hydrogels with the unique attributes to be prepared at various concentrations and photocrosslinked (requires a photoinitiator) to provide various gel stiffness. The PhotoGel kit consists of purified methacrylated porcine gelatin and a photoinitiator. The gelatin is type A 300 bloom. PhotoGel is produced from methacrylated gelatin where the gelatin has been modified by reacting the free amines, primarily the ε-amines groups of the lysine residues as well as the a-amines groups on the N-termini. The photoinitiator consists of Irgacure 2959 to be formulated in methanol (methanol not included) which allows UV crosslinking of the gelatin at 365 nm.
Revvity Health Sciences Inc AlphaLISA Human IL1-RA Detection Kit, Standard
AlphaLISA Human IL1-RA Detection Kit, Standard
Genscript Corporation FGF-R2 Human
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 is a receptor for fibroblast growth factor and it has important roles in embryonic development and tissue repair especially bone and blood vessels FGFR2 has two naturally occurring isoforms FGFR2IIIb and FGFR2IIIc created by splicing of the third immunoglobulin-like domain FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining Like the other members of the fibroblast growth factor receptor family these receptors signal by binding to their ligand and dimerisation (pairing of receptors) which causes the tyrosine kinase domains to initiate a cascade of intracellular signals On a molecular level these signals mediate cell division growth and differentiation
Biolegend Brilliant Violet 650TM anti-hu
Brilliant Violet 650™ anti-human CD134 (OX40) [Ber-ACT35 (ACT35)]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
Bioss Thyroid hormone receptor alpha
Thyroid hormone receptor alpha Primary Antibody Unconjugated Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
Medchemexpress LLC HY-P7228 10ug Medchemexpress, I-TAC/CXCL11 (HEK293-expressed), Human CAS: Purity:>98%
Medchemexpress, HY-P7228 10ug I-TAC/CXCL11 (HEK293-expressed), Human CAS: Recombinant Human I-TAC/CXCL11 (HEK293-expressed) is a small cytokine belonging to the CXC chemokine family which can be strongly induced by IFN-gamma, and its receptor CXCR3. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Meso Scale Discovery U-PLEX Rat FGF-21 ASY384-well
The Meso Scale Discovery U-PLEX Rat FGF-21 384-Well Assay Kit is a 384-well electrochemiluminescent immunoassay for the quantitative measurement of FGF-21 in rat serum plasma and cell culture supernatants The assay uses MSD GOLD Streptavidin Multi-Array plates and a proprietary ruthenium labeled detection antibody to provide high sensitivity and a wide dynamic range The kit includes a calibrator to generate a standard curve and reagents for up to 384 tests in a 384-well plate format The streamlined no-wash protocol provides results in under 3 hours The assay has high sensitivity with an LLOQ of 1 15 pg/mL and requires as little as 25 L of sample
Revvity Health Sciences Inc HTRF Human CXCL1 Detection Kit Standard
HTRF Human CXCL1 Detection Kit Standard
CPC Scientific H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH (trifluoroacetate salt) 0.5MG
EGFR fragment that contains the autophosphorylation site at Tyr992.ONE-LETTER SEQUENCE: DVVDADEYLIPQMOLECULAR FORMULA: C61H93N13O23MOLECULAR WEIGHT:1376.5STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [96249-43-3], RESEARCH AREA: CancerREFERENCES: A. Ullrich et al., Nature, 309, 418 (1984)
Sino Biological TNF-alpha / TNFA / TNFSF2 Antibody (HRP), Mouse MAb 100ug
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNF-alpha / TNFA / TNFSF2 (rh TNF-alpha / TNFA / TNFSF2; Catalog#10602-HNAE; NP_000585.2; Val77-Leu233). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).