Use fibroblast growth factor acidic (FGF-acidic) to activate DNA synthesis, cell proliferation, and chemotaxis, as well as regulate development, regeneration, and angiogenesis (Jaye et al. Science, 1986; Galzie et al. Biochem Cell Biol, 1997; Presta et al. Cytokine Growth Factor Rev, 2005). FGF-acidic signals through protein kinase C, promoting cell survival by inhibiting p53 and proapoptotic signaling (Bouleau et al. Oncogene, 2005). FGF-acidic is found in large quantities in the brain and is capable of activating all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. Human recombinant FGF-acidic from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 0.3 ng/mL; endotoxin levels verified ≤ 0.2 EU/μg protein. Alternative names: Acidic fibroblast growth factor, aFGF, ECGF, Endothelial cell growth factor, FGF-1, FGF-alpha, Fibroblast growth factor 1, GLIO703, HBGF-1, Heparin-binding growth factor 1. Visit STEMCELL.com for more information.