Cell Lines and Cell Cultures
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Olfactory ( region), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
CPC Scientific H-His-Ala-Glu-Lys-His-Trp-Phe-Val-Gly-Leu-OH (trifluoroacetate salt) 1MG
ONE-LETTER SEQUENCE: HAEKHWFVGLMOLECULAR FORMULA: C59H82N16O13MOLECULAR WEIGHT:1223.40STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [198542-00-6]span>
SYNONYMS: FGF acidic I (102-111) (bovine brain)
RESEARCH AREA: Cancer
REFERENCES:
G. Gimenez-Gallego et al., Science, 230, 1385 (1985),
Eurofins Discoverx PathHunter U2OS OX40 Signaling Assay, 2 vials. (93-1080C3)
The PathHunter OX40 Checkpoint Signaling cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting signaling checkpoints. This cell line enables assessment of OX40 induced non-canonical NF-κB signaling via detection of NIK stabilization. This product uses EFC technology. The included cell line overexpresses ED-tagged NIK (NF-kappa-B Inducing Kinase) protein as well as untagged OX40 receptor. Upon activation of the receptor by its ligand or an antibody, NIK is stabilized, allowing detection of EFC signal when treated with exogenous EA. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
Eurofins Discoverx ChemiScreen NK3 Tachykinin Receptor Stable Cell Line, 2 vials. (HTS190C)
The ChemiScreen NK3 Tachykinin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. tachykinins) based activation of TACR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TACR3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TACR3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Medchemexpress LLC CD47 protein, rat (HEK293, Fc) | 95.0% | 1 MG
Recombinant rat CD47 extracellular domain produced in HEK293 cells and presented as a C-terminal human Fc fusion protein. Intended for research use in in vitro binding studies, biochemical characterization, and assay development. Supplied purified and frozen to preserve structural integrity and activity.
- Recombinant rat CD47 extracellular domain.
- Expressed in HEK293 mammalian cells.
- C-terminal human Fc fusion tag for stability and detection.
- Purity approximately 95.0%.
- Supplied frozen; store at -20°C.
- Available in a 1 mg format.
Medchemexpress LLC CD47 protein, rat (HEK293, His-tag) | >95.0% | 50 UG
Recombinant rat CD47 extracellular domain (residues Q19-K140) expressed in HEK293 cells with a C-terminal His tag. Supplied lyophilized and purified for biochemical assays, antibody validation, and receptor-ligand interaction studies; reconstitution and carrier protein recommendations are provided for long-term stability.
- Expression host: HEK293 cells.
- Tag: C-terminal His.
- Sequence range: Q19-K140.
- Purity: >95% by reducing SDS-PAGE.
- Formulation: lyophilized from 0.22 μm-filtered PBS, pH 7.4.
- Storage guidance: stable frozen; add carrier protein for long-term storage after reconstitution.
ATCC Chaetomium globosum; purified DNA 2ug
Genomic DNA isolated from Chaetomium globosum. This fungal strain is also available as ATCC Catalog No.: 6205™.
Eurofins Discoverx PathHunter CHO-K1 CHRM4 β-Arrestin Cell Line, 2 vials. (93-0349C2)
The PathHunter CHRM4 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CHRM4 and EA-tagged β-Arrestin-2. Activation of CHRM4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Frozen Tissue Section - Arteriosclerosis: Artery, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biolegend Brilliant Violet 605TM anti-hu
Brilliant Violet 605™ anti-human TCR Vδ2 [B6]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
Eurofins Discoverx ChemiScreen M5 Acetylcholine Muscarinic Receptor Stable Cell Line, 2 vials. (HTS075C)
The ChemiScreen M5 Acetylcholine Muscarinic Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM5 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM5, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen B2 Bradykinin Receptor Stable Cell Line, 2 vials. (HTS041C)
The ChemiScreen B2 Bradykinin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. bradykinin) based activation of BDKRB2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses BDKRB2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of BDKRB2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx cAMP Hunter DLD1 ADRB3 Gs Cell Line, 2 vials. (95-0182C13)
The cAMP Hunter ADRB3 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. epinephrine and norepinephrine) based activation of ADRB3 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB3, a naturally Gs coupled GPCR. Upon activation of ADRB3, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
