General Cell Lines and Cell Cultures
ATCC AR230-r; Chronic myeloid leukemia; Human (Homo sapiens)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC UACC-893; Breast Carcinoma; Human (Homo sapiens)
UACC-893 is a cell line exhibiting epithelial-like morphology that was isolated from the mammary gland of a White, 57-year-old, female patient with ductal carcinoma. This cell line was deposited by A Liebovitz, J Trent, and can be used in cancer research.
Eurofins Discoverx PathHunter CHO-K1 mGCGR β-Arrestin-1 Cell Line, 2 vials. (93-0973C2)
The PathHunter mGCGR (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. glucagon) based activation of mGCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGCGR and EA-tagged β-Arrestin-1. Activation of mGCGR stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS TORC1 Nuclear Translocation Cell Line, 2 vials. (93-0833C3)
The PathHunter U2OS TORC1 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the CRTC/CREB pathway. This cell line enables assessment of ligand (e.g. forskolin) based pathway activation via detection of resulting TORC1 (CRTC1) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged TORC1 (CRTC1) and nuclear localized EA. Upon pathway activation, induced nuclear translocation of TORC1 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Promocell GmbH PromoCell HAoSMC-c 500,000 Human Aortic Smooth Muscle Cells, cryopreserved
Primary Human Aortic Smooth Muscle Cells (HAoSMC) are isolated from plaque-free regions of the human aorta and stain positive for smooth muscle α-actin. The pulsatile pressure produced by the heart causes a cyclic distention of the aorta. The smooth muscle cells in the aortic wall subsequently contract it again. Changes in the arterial wall, associated with vascular diseases such as atherosclerosis and hypertension, strongly influence this process.HAoSMC are suitable for studying the role of smooth muscle cells under normal or disease conditions in vitro.Our HAoSMC are now also available from HLA-typed and Diabetes Type I and Type II donors.
ATCC HCM-CSHL-0094-C25; Cancer Model Primary; Pancreatic Ductal Adenocarcinoma; Human (Homo sapiens)
A patient-derived next-generation cancer model generated by the Human Cancer Models Initiative (HCMI). HCM-CSHL-0094-C25 (ATCC No. PDM-41) was isolated from primary ductal adenocarcinoma of pancreas tissue. This tumor-derived model can be used in basic research and pharmacological screening applications. Data for the parental tumor and the tumor-derived organoid models are available at the GDC. Additional molecular characterizations may be available at the GDC. Additional controlled data may be available via dbGaP.
Eurofins Discoverx PathHunter DLD1 IL7R/CRLF2 Dimerization Cell Line, 2 vials. (93-1019C13)
The PathHunter IL7R/CRLF2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. TSLP) induced dimerization of IL7R/CRLF2 receptors. This product uses EFC technology. The cell line included overexpresses IL7R target protein fused to PK alongside CRLF2 target protein fused to EA. Upon ligand-induced dimerization of IL7R/CRLF2, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
SCIENCELL RESEARCH LABORATORIES INC HUMAN LYMPHATIC FIBROBLASTS
NC2014033 HUMAN LYMPHATIC FIBROBLASTS
ATCC Neisseria gonorrhoeae; genomic DNA
Genomic DNA isolated from Neisseria gonorrhoeae strain FA1090. This whole-genome sequenced product has applications in PCR and other molecular biology research.