General Cell Lines and Cell Cultures
Cell Systems Corporation Primary Human Retinal Microvascular Endothelial Cells (ACBRI 181 V)
Primary Human Retinal Microvascular Endothelial Cells (ACBRI 181 V) were initiated from normal human retinal tissue. Unlike cells from other providers, our primary cells are isolated without positive control antibody labels for enhanced biological relevance. Each vial contains ~1 x 10^6 cells with 85-92% viability under ideal conditions. They are available at Passage 3 (<12 cumulative population doublings) and will initiate a Passage 4 cell culture in a 75 cm2 flask. Each vial of cells is shipped with Bac-Off (antibiotic) and CultureBoost (animal derived growth factors) at no additional cost. You can enhance consistency in your research program with reserved lots. Need vials in bulk? Contact your Fisher Scientific Sales representative for tailored quotes. Tight Deadline? Our cells are available for next day delivery after the purchase order is received. Accelerate Your Research! Try our Attachment Factor (4Z0-201, 4Z0-210) – innovative 5 seconds plating solution for all surfaces.
ATCC Pfizer Pneumococcal polysaccharide powder Type 25 (d25F) 10mg
Purified pneumococcal polysaccharide type 25F is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 25F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx PathHunter P2RY12 Total Internalization U2OS Cell Line, 2 vials. (93-0952C3)
The PathHunter P2RY12 Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of P2RY12 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged P2RY12 and a ProLink-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the P2RY12 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter Rhesus TrkA-P75 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Rhesus TrkA-P75 Stable Cell Line Functional Kinase Assay (U2OS) measures TrkA-P75 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter CHO-K1 ADRB1 Gs Cell Line, 2 vials. (95-0113C2)
The cAMP Hunter ADRB1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB1, a naturally Gs coupled GPCR. Upon activation of ADRB1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/ACE2 Stable Cell Line
Recombinant CHO-K1 cells stably express Angiotensin-converting enzyme 2 (ACE2) on the cell surface The surface expression of ACE2 is validated by FACS analysis This stable cell line product is designed for cell-based binding assays that measure binding affinity and stability of antibody based biologics binding with ACE2
Sigma Aldrich Fine Chemicals Biosciences Skeletal Muscle Cell Growt
Skeletal Muscle Cell Growth Medium Kit
ATCC Aspergillus flavus; SN 3; genomic DNA
Genomic DNA isolated from Aspergillus flavus SN 3 (ATCC 9643). This product can be used for PCR or other molecular biology applications.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Submaxillary gland, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Uterus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Genscript Corporation CHO-K1/MTLR/G15 Stable Cell L
The motilin receptor (MTLR) represents a clinically useful pharmacological target as agonists binding to the MTLR have gastroprokinetic properties Motilin is a 22 amino acid peptide that potently stimulates gastrointestinal contractility The biological effects of motilin are mediated by a G sub q /sub -coupled seven transmembrane protein currently termed motilin receptor (MR) that shares significant sequence similarity with the ghrelin receptor The motilin receptor is also activated by the antibiotic erythromycin this interaction appears to mediate some of the gastrointestinal side effects of erythromycin Although motilides (non-antibiotic derivatives of erythromycin) such as ABT-229 have been investigated for treatment of diabetic gastroporesis the effectiveness has been limited by tachyphylaxis (decreased response to ligand) resulting from receptor downregulation Agonists of the motilin receptor with reduced densensitization activity remain a potential treatment for dis
Eurofins Discoverx PathHunter U2OS PRα Protein Interaction Cell Line, 2 vials. (93-0852C3)
The PathHunter PRα Protein Interaction cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting NHR activation and recruitment of cofactors. This cell line enables assessment of ligand (e.g. testosterone, norgestrel) based NHR activation via detection of SRCP (steroid receptor co-activator peptide) recruitment. The included cell line overexpresses ProLink-tagged PRα (progesterone receptor alpha) NHR and EA-tagged steroid receptor co-activator peptide (SRCP). Upon activation of PRα, induced interaction with SRCP leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
ATCC Quantitative Genomic; DNA from Bacteroides; fragilis strain VPI 2553
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Saccharomyces cerevisiae; purified DNA 5ug
Genomic DNA isolated from Saccharomyces cerevisiae ATCC 4040005. This fungal strain is also available as ATCC Catalog No.: 201390™.