General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter CHO-K1 CRHR2 β-Arrestin Cell Line, 2 vials. (93-0251C2)
The PathHunter CRHR2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CRH, sauvagine) based activation of CRHR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CRHR2 and EA-tagged β-Arrestin-2. Activation of CRHR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC H9c2(2-1); Embryonic Myocardium; Rat (Rattus norvegicus)
H9c2(2-1) is a subclone of the original clonal cell line derived from embryonic BD1X rat heart tissue that exhibits many of the properties of skeletal muscle. This cell line can be used in cardiovascular disease research.
American Research Products Inc Mouse Triggering receptor eXpr
Mouse Triggering receptor eXpressed on myeloid cells 2 (TREM2) ELISA kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Amsbio LLC Jurkat T / GFP Stable Cell (Survivin Promoter)
Jurkat T / GFP Stable Cell (Survivin Promoter)
ATCC HT-2 clone A5E; Spleen; Mouse (Mus musculus)
HT-2 clone A5E is a lymphocyte cell line that was isolated in 1979 from the spleen of a mouse. This cell line was deposited by JF Weaver, A Creasey, and can be used in immunology research.
ATCC A549 Exosomes; Lung Carcinoma; Human (Homo sapiens)
Exosomes are subcellular nanoparticles of size 50-200 nm released from cells through a fusion of multicellular bodies with plasma membrane. The exosomes are purified from cell culture medium of lung carcinoma cell line A549 (ATCC CCL-185). The exosomes are purified and concentrated using tangential flow filtration system in a sterile environment. The purified exosomes were further filtered through 0.2 micron sterile filters.
ATCC DU 145; Prostate Carcinoma; Human (Homo sapiens)
DU 145 is a cell line with epithelial morphology that was isolated from the brain of a 69-year-old, White, male with prostate cancer. This cell line is suitable as a transfection host.
Eurofins Discoverx ChemiScreen CCR3 Chemokine Receptor Stable Cell Line, 2 vials. (HTS008C)
The ChemiScreen CCR3 Chemokine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. eotaxin) based activation of CCR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CCR3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CCR3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay CCR4 Chemokine Receptor Frozen Cells, 2 Vials of Cells. (HTS009RTA)
The Ready-to-Assay CCR4 Chemokine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. MIP, RANTES) based activation of CCR4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CCR4 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CCR4, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Promocell GmbH PromoCell HUtSMC Pellet from > 1 million Normal Human Uterine Smooth Muscle Cells
Cell pellet consisting of 1 million cells dissolved in 200µl RNAlater for subsequent RNA, DNA or protein analysis. Note: Cell pellets cannot be revived.Our Cell Pellets are stored in RNAlater – an aqueous protection solution that rapidly permeates the cells and stabilizes cellular DNA, RNA, and proteins and protects them from degradation. This makes our Cell Pellets very useful for a wide range of research applications like gene expression analysis, cell characterization studies, and protein characterization experiments.Each Cell Pellet is made from 1 million cells and is dissolved in 200 µl RNAlater. The Cell Pellets are produced from released cell lots and have the same characteristics, i.e. expression profile or cell type specific antigens. On request, viable cells from the same lot are available for cultivation.
Biochain Institute Inc Paraffin Tissue Section - Human Angioma: Glomus Tumor, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Human respiratory; syncytial virus; Strain: 18537; RNA
Viral nucleic acids, including viral genomic RNA, in total RNA isolated from Hep-2 cells (ATCC CCL-23) infected with Human respiratory syncytial virus strain 18537 (ATCC VR-1580). Virus and host cells are also available through the ATCC catalog. This product was prepared using methods known to inactivate viruses. RNA isolated from virally infected cells can be used for RT-PCR and other molecular virology applications.
ACROBiosystems HEK293/Human PTK7 Stable Cell Line
PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Promocell GmbH PromoCell HDLEC-c 500,000 Human Dermal Lymphatic Endothelial Cells, adult, cryopreserved
Primary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.The cells are routinely analyzed by flow cytometric analysis and immunofluorescent staining:> 95% of the cells are CD31 positive and podoplanin positive.Lymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.
STEMCELL Technologies Human Peripheral Blood Mononuclear Cells, Frozen
Streamline your assays with ready-to-use, ethically sourced, primary human mononuclear cells. With personalized service, flexible delivery times, and the option to reserve entire lots to prescreen cells for applications, we help you get the cells you need. Isolated from peripheral blood leukapheresis samples using density gradient separation and/or red blood cell lysis and cryopreserved in animal component-free CryoStorCS10 medium (Catalog #07930), cells are collected using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation and high-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. Acid-citrate-dextrose solution A (ACDA) is added during collection as an anticoagulant. Donor specifications (e.g. BMI category, smoking status, ethnicity, etc.) can be requested. Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C.Certain products are only available in select territories.