General Cell Lines and Cell Cultures
ATCC Cell Basement Membrane
Cell Basement Membrane is purified from murine Engelbreth-Holm-Swarm (EHS) tumor. Cell Basement Membrane has applications in the three-dimensional culture of primary tissue-derived human and mouse organoids, a 3-D culture of iPSC-derived organoids, patient-derived organoids, a 3-D culture of tumorspheres from various cell lines, and a sandwich culture of human hepatocytes. Cell Basement Membrane is a feeder-free culture of human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC), a culture of iPSCs-derived neural progenitor cells (NPCs) and neurons, and angiogenesis modeling via the tube formation assay.
Creative Bioarray CAL-51 Cell Line, Triple-Negative Breast Cancer, 80% DMEM + 20% h.i.FBS, Patient Age 45, Female, Derived from Pleural Effusion Metastasis, Tumorigenic in Nude Mice, MSI-low, Epithelial-like Morphology
The CAL-51 cell line serves as a vital in vitro model for aggressive breast cancer research, particularly in the realm of triple-negative breast cancer (TNBC). Derived from a pleural effusion metastasis, this human cell line demonstrates unique properties such as adherent growth, an epithelial-like morphology, and a normal diploid karyotype. CAL-51 lacks the expression of estrogen receptors, progesterone receptors, and HER2, positioning it as an invaluable tool for studying various aspects of TNBC, including tumorigenicity and therapeutic resistance. Its documented use in preclinical studies, including those involving SARS-CoV-2, further enhances its utility for research and drug development.
ATCC Pfizer Pneumococcal polysaccharide powder Type 17 (d17F) 200mg
Purified pneumococcal polysaccharide type 17F is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 17F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx CHO-K1 EDG4 Gq Cell Line, 2 vials. (95-1012C2)
The EDG4 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. LPA) based activation of EDG4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses EDG4, a naturally Gq coupled GPCR. Upon activation of EDG4, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CCR2 Total GPCR Internalization U2OS Cell Line, 2 vials. (93-0679C3)
The PathHunter CCR2 Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CCR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CCR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CCR2 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen P2Y2 Purinergic Receptor Stable Cell Line, 2 vials. (HTS210C)
The ChemiScreen P2Y2 Purinergic Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP, UTP) based activation of P2RY2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses P2RY2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of P2RY2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Lonza Walkersville SE Cell Line 96-well Nucleofector Kit
The SE Cell Line 96-well Nucleofector Kit is one of our three kits suited for medium-throughput transfection of cell lines when working with the 4D-Nucleofector 96-well Unit.Benefits:High transfection efficiencies in difficult-to-transfect cell linesCompatible with liquid handling systems for automated high-throughput electroporationConditions are transferable between 4D Nucleofector System, 4D-Nucleofector 96-well Unit and 384-well Nucleofector SystemApplications:Transfection of low cell numbers in the range of 5 x 10⁴ to 1 x 10⁶ cellsHigh-throughput applications, e.g. screens of arrayed cDNA, RNAi or CRISPR librariesContent:2.25 mL SE Cell Line Nucleofector Solution0.5 mL Supplement 150 µg pmaxGFP Vector (1 μg/μl in 10 mM Tris pH 8.0)1 x 96-well Nucleocuvette Plate (20 μL)
Vector Biolabs codon-optimized FLP (FLPo) with RFP Adenovirus (Ad-RFP-FLPo)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA
Biochain Institute Inc Matched Pair - Total RNA - Human Primary and Metastatic Tumor Tissue: Breast, 2x10 ug/PK
BioChain's human total RNA matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of total RNA isolated from primary tumor and its adjacent normal tissue; PM consists of total RNA from primary tumor and and corresponding metastatic tumor. Total RNA in each pair is prepared from the same donor. This product line is designed for identifying tumor-specific genes and tumor metastatic genes.
ATCC VA-ES-BJ; Epithelioid Sarcoma; Human (Homo sapiens)
VA-ES-BJ is a cell line exhibiting epithelial morphology that was isolated from a 41-day-old, White male patient with epithelioid sarcoma. It has applications in immunology and cancer research.
ATCC Human adenovirus 2; Strain: Adenoid 6
Human adenovirus 2 strain Adenoid 6 is propagated in MRC-5 cells (ATCC CCL-171). This strain was isolated in 1953 from a 7-year-old human female with hypertrophied tonsils and adenoids and was deposited by NIH/NIAID. This product has applications in infectious and respiratory research.
ACROBiosystems CHO/Human CD64 Stable Cell Line (High Expression) Development Service
Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses.High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.
ATCC hTERT FT 240; Fimbriae Epithelium; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.