General Cell Lines and Cell Cultures
Genscript Corporation CHO-K1/BDCA2 and FcER1G Stable
Recombinant CHO-K1 cells stably overexpress human C-type lectin domain family 4 member C (BDCA2) and Fc epsilon receptor Ig (FcER1G) on the surface The surface expression of BDCA2 is validated by FACS analysis
ATCC NRK; Kidney; Rat (Rattus norvegicus)
NRK is a rat kidney cell line exhibiting epithelial morphology that was isolated from a normal adult rat. This product can be used in cancer and to study renal physiology.
Discovery Life Sciences Breast Cancer Active Tx PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
ATCC Klebsiella pneumoniae; Strain 1002565
Klebsiella pneumoniae subsp. pneumoniae strain 1002565 is a whole-genome sequenced bacterium that was isolated from a respiratory sample. This strain is resistant to ertapenem and imipenem and was confirmed by PCR to contain the blaNDM gene. This bacterial culture can be used in antimicrobial resistance research, drug development, infectious disease research, and respiratory disease research.
Eurofins Discoverx PathHunter U2OS IL17RA/IL17RB Dimerization Cell Line, 2 vials. (93-1150C3)
The PathHunter IL7RA/IL7RB Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-17E) induced dimerization of IL7RA/IL7RB receptors. This product uses EFC technology. The cell line included overexpresses IL17RB target protein fused to PK alongside IL17RA target protein fused to EA. Upon ligand-induced dimerization of IL7RA/IL7RB, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
ATCC Chlamydia trachomatis; Serovar D; Strain: UW-3/Cx
Chlamydia trachomatis serovar D strain UW-3/Cx is propagated in McCoy [McCoy B] cells (ATCC CRL-1696). This strain was isolated from the cervix of an asymptomatic human patient. This product has applications in infectious disease and sexually transmitted disease research.
Eurofins Discoverx ChemiScreen Rhesus Macaque CCR5 Chemokine Receptor Stable Cell Line, 2 vials. (HTS010C)
The ChemiScreen Rhesus Macaque CCR5 Chemokine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. MIP, RANTES) based activation of CCR5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CCR5 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CCR5, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the rhesus macaque version of the protein. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC RD; Rhabdomyosarcoma; Human (Homo sapiens)
Rhabdomyosarcoma (RD) cells are large, multinucleated, spindle-shaped cells isolated from muscle tissue. Use this cell line for your research and for the detection of viruses.
ATCC Blastomyces dermatitidis; purified DNA 2ug
Genomic DNA isolated from Blastomyces dermatitidis Gilchrist et Stokes strain SCB2. This fungal strain is also available as ATCC Catalog No.: 26199™. Organism: Blastomyces dermatitidis strain SCB-2 Depositor: RA Cox
Eurofins Discoverx PathHunter U2OS CDC25A Degradation Cell Line, 2 vials. (93-0765C3)
The PathHunter U2OS CDC25A Degradation Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the cell cycle checkpoint pathway. This cell line enables detection of levels of CDC25a, allowing for assessment of CHK-1-activation-induced CDC25a degradation. This product uses EFC technology. The cell line included overexpresses CDC25a target protein fused to ProLabel. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of CDC25a EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Eurofins Discoverx PathHunter HEK 293 cyno CXCR1 β-Arrestin Cell Line, 2 vials. (93-0980C1)
The PathHunter cyno CXCR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL8/IL8) based activation of CXCR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged cyno CXCR1 and EA-tagged β-Arrestin-2. Activation of CXCR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Cynomolgus monkey version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Providencia alcalifaciens
This culture is a bacterial type strain that was isolated from feces. It can be used in quality control testing and produces restriction endonuclease PalI.
ATCC UWB1.289; Ovarian Carcinoma; Human (Homo sapiens)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Vector Biolabs human BECN1 shRNA Adenovirus (Ad-h-BECN1-shRNA)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA