General Cell Lines and Cell Cultures
ATCC Cryptococcus gattii; WM779
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Bordetella pertussis; Strain: H762
Bordetella pertussis strain H762 is a bacterium that was isolated in 2011 from a human in the United States. The depositor states that this culture is pertactin negative.
TARGETMOL CHEMICALS INC ENDOTHELIAL LIPASE INHIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM. purity: 97%
ATCC Escherichia coli; Bacteriophage PR772
This is a PR4-like bacteriophage. It is sensitive to organic solvents and adsorbs to tips of pili coded for by IncP-1, N, and W plasmids.
Eurofins Discoverx Ready-to-Assay Secretin Glucagon Receptor Frozen Cells, 2 Vials of Cells. (HTS174RTA)
The Ready-to-Assay Secretin Glucagon Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SCTR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of SCTR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Streptomyces nodosus
Streptomyces nodosus strain SC 2388 is a whole-genome sequenced bacterial type strain that was isolated in Venezuela from soil from the Orinoco River. This strain produces amphotericin A.
ATCC C2C12 scrambled; Myoblast; Mouse (Mus musculus)
C2C12 Scrambled is a cell line with myoblast morphology that was isolated in 2013 from the skeletal muscle of a mouse. The cell line was created by transfecting C2C12 cells with scrambled shRNA. The scrambled shRNA is maintained in the cell line by growing the cells with 2 μg/ml puromycin. Cells show same levels of dysferlin expression as wild type cells. This is the control cell line for C2C12 Clone 5 DYS shRNA (ATCC CRL-3418). This cell line can be used to study membrane repair and muscle regeneration mechanisms.
ATCC Kocuria rhizophila; 6 x 0.3mL
ATCC 9341-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 9341™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Sciencell Research Laboratories Human Mammary Vascular Endothelial Cells
HMVEC from ScienCell Research Laboratories are isolated from human breast. HMVEC are cryopreserved after purification and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume.
ATCC Clostridium perfringens; 6 x 0.3mL
ATCC 13124-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 13124™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
ATCC HCM-CSHL-0090-C25; Cancer Model Primary; Pancreatic Ductal Adenocarcinoma; Human (Homo sapiens)
A patient-derived next-generation cancer model generated by the Human Cancer Models Initiative (HCMI). HCM-CSHL-0317-C18 (ATCC No. PDM-359) was isolated from primary cancer of colon tissue. This tumor-derived model can be used in basic research and pharmacological screening applications. Data for the parental tumor and the tumor-derived organoid models are available at the GDC. Additional molecular characterizations may be available at the GDC. Additional controlled data may be available via dbGaP.
Eurofins Discoverx PathHunter Cyno IL-8 (CXCR1) β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Cyno IL-8 (CXCR1) β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure cyno CXCR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human NPFFR1 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human NPFFR1 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NPFFR1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ATCC Clostridioides difficile
This strain of Clostridioides difficile was isolated from a clinical specimen. It is toxigenic (toxinotype IIIc) and was confirmed by PCR to have the cdtB, tcdA, and tcdB genes. This product has applications in enteric disease research.
Eurofins Discoverx PathHunter CHO-K1 mCCR9 β-Arrestin Cell Line, 2 vials. (93-0734C2)
The PathHunter mCCR9 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL25) based activation of mCCR9 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR9 and EA-tagged β-Arrestin-2. Activation of mCCR9 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.