General Cell Lines and Cell Cultures
ATCC Listeria monocytogenes; serotype 4b
Listeria monocytogenes strain Li 2 was isolated from a human and has applications in bioinformatics, enteric disease research, infectious disease research, zoonotic disease research and as a quality control.
ATCC Microbacterium testaceum
Microbacterium testaceum strain Rp-3 is a whole-genome sequenced bacterial type strain with utility as a quality control strain.
ATCC Azotobacter vinelandii; Strain DJ
Azotobacter vinelandii strain DJ is a whole-genome sequenced bacterium. This strain is grown aerobically on Azobacter supplement media.
Eurofins Discoverx PathHunter CHO-K1 CCR5 β-Arrestin Cell Line, 2 vials. (93-0224C2)
The PathHunter CCR5 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL3/MIP-1α) based activation of CCR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR5 and EA-tagged β-Arrestin-2. Activation of CCR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Promocell GmbH PromoCell Supplement Mix / Preadipocyte Growth Medium
PromoCell Preadipocyte Growth Medium is a low-serum (5% V/V) medium developed for the undifferentiated expansion of human preadipocytes.Although all PromoCell media are optimized for use with primary human cells, we have received feedback from customers that this particular medium can also be used for murine preadipocytes/adipocytes.Components:* Growth Medium (Ready-to-use): Includes Basal Medium and SupplementMix* Growth Medium Kit: Includes Basal Medium and SupplementPack* SupplementMix: Contains all media supplements premixed in one vial* SupplementPack: Contains all media supplements as individual vials| Media supplement | Final supplement concentration|| Fetal Calf Serum | 0.05 ml / ml || Endothelial Cell Growth Supplement | 0.004 ml / ml || Epidermal Growth Factor (recombinant human) | 10 ng / ml || Hydrocortisone | 1 μg / ml || Heparin | 90 μg / ml |
Promocell GmbH PromoCell HFDPC-c 500,000 Human Follicle Dermal Papilla Cells, derived from skin, cryopreserved
Primary Human Follicle Dermal Papilla Cells (HFDPC) are isolated mainly from human dermis of the scalp, originating from the occipital or temple region. Information on donor hair and skin color is available on request. HFDPC stain positive for alkaline phosphatase.Dermal papillae are embedded in a laminin and collagen IV rich extracellular matrix at the base of the hair follicles. They are essential for the induction and maintenance of hair growth. Since they have androgen receptors, they can be used for in vitro screening of androgen blocking reagents.
Eurofins Discoverx Ready-to-Assay CCR9 Chemokine Receptor Frozen Cells, 2 Vials of Cells. (HTS036RTA)
The Ready-to-Assay CCR9 Chemokine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. CCL25/TECK) based activation of CCR9 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CCR9 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CCR9, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter U2OS mRHO(P23H) MEM-EA Pharmacotrafficking Assay, 2 vials. (93-1077C3)
The PathHunter U2OS mRHO(P23H) MEM-EA Pharmacotrafficking Assay is a stable, engineered cell line for use in studying pharmacochaperones targeting mRHO. This cell line enables assessment of chaperone-based stabilization of mRHO(P23H) via detection of rescued membrane trafficking. The included cell line overexpresses ProLink-tagged mutant mRHO(P23H), which is misfolded and retained in the ER. The cell line also expresses membrane-localized EA. When a pharmacochaperone stabilizes the mutant mRHO, it is trafficked to the membrane, producing EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Lung Tumor and Normal Tissue Array 60 spots: Duplicated spots from lung tumor tissues (25 donors) and lung normal tiss, 2 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
Biochain Institute Inc Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Kidney, 5 x2 slides /PK
BioChain's human paraffin tissue section (FFPE) matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). ??PP consists of paraffin tissue sections of primary tumor and its adjacent normal tissue; PM consists of paraffin tissue sections of primary tumor and corresponding metastatic tumor. Paraffin tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor- specific genes and tumor metastatic genes.
Eurofins Discoverx cAMP Hunter CHO-K1 GPBAR1 Gs Cell Line, 2 vials. (95-0049C2)
The cAMP Hunter GPBAR1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPBAR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GPBAR1, a naturally Gs coupled GPCR. Upon activation of GPBAR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS TrkC Functional Assay, 2 vials. (93-0464C3)
The PathHunter U2OS TrkC Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TrkC dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TrkC and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Trichophyton interdigitale; 640
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.