Sera
IPHASE PHARMA SERVICES LLC Wistar Han Rat Liver Microsomes,Female,0.5mL,20mg/mL
A major tool for metabolism stability study. Our liver microsomes products available in multi-species (human, monkey, beagle, rat, and mouse). We also offer customized products prepared from unconventional animal species, disease models, or animals of certain ages.
Sino Biological Cynomolgus CD127 / IL-7RA Protein (His Tag), Endotoxin-Free 100µg
A DNA sequence encoding the cynomolgus IL7R (NP_001271837.1) (Met1-Pro235) was expressed with a polyhistidine tag at the C-terminus.
Cayman Chemical R3Oxocyclopentncarboxy 50mg
A synthetic intermediate useful for pharmaceutical synthesis.
Cayman Chemical SerotonInhydrochlorIde 100mg
A monoamine neurotransmitter produced in serotonergic neurons in the CNS and in enterochromaffin cells in the gastrointestinal tract that is important in the regulation of mood, sleep, vomiting, sexuality, and appetite
Cayman Chemical TMPyP4tosylate 100mg
A cationic porphyrin that intercalates into and stabilizes G-quadruplexes; inhibits telomerase activity (IC50 ≤ 50 µM), blocking the clonogenic growth and migration of cancer cells in culture and in vivo
Cayman Chemical NItrendIpIn 50mg
A dihydropyridine used as an antihypertensive agent due to its ability to block L-type and T-type calcium channels; also binds to adenosine A1, A2A, and A3 receptors with Ki values of 8.96, 23.0, and 8.3 µM, respectively
Cayman Chemical CatharnthIntartrate 50mg
An indole alkaloid with diverse biological activities; a precursor in the biosynthesis of the vinblastine and vincristine; inhibits microtubule assembly at 320 µM; inhibits proliferation of HCT116 cells (IC50 = 60 UG/ml); induces the release of amylase from mouse pancreas preparations at 100 µM; decreases blood pressure and heart rate in anesthetized normotensive rats at 0.5-20 mg/kg
Cayman Chemical HydroxychloroquInsulfate 100mg
An aminoquinoline with antimalarial and anti-inflammatory activities; active against the chloroquine-sensitive NF54 and D6 strains of P. falciparum (IC50s = 16.3 and 15 nM, respectively) but has decreased activity against chloroquine-resistant P. falciparum strains (IC50s = 422.7-1,735.3 nM); inhibits TPA- and ionomycin-induced production of IL-22, IL-17A, and IL-6 in PBMCs isolated from healthy individuals or patients with SLE or RA; inhibits accumulation of SQSTM1 puncta in MEFs; reduces SARS-CoV-2 viral titers in the culture supernatant of infected Vero E6 cells but does not reduce SARS-CoV-2 viral titers in an in vitro human airway epithelium model or the respiratory tract of SARS-CoV-2 infected cynomolgus macaques
Cayman Chemical RhodamIn 123chlorIde 100mg
A membrane-permeable cationic dye that is a substrate for P-gp and is rapidly exported from cells with functional P-gp; also accumulates within mitochondria and can inhibit oxidative phosphorylation; ex/em = 507/529 nm
Cayman Chemical 1R 3S3Hydroxycyclopentn 50mg
A synthetic intermediate useful for pharmaceutical synthesis.
Cayman Chemical SulconazolenItrate 50mg
An azole antifungal; active against dermatophyte fungal species, including isolates of various Candida species; non-specific inhibitor of styrene metabolism by cytochrome P450 (CYP450) enzymes; inhibits various CYP450 isoforms in human lymphoblast microsomes in vitro (Kis = 0.008-3.5 µM); inhibits heme oxygenase 1 activity in rat spleen microsomes (IC50 = 1.1 µM); inhibits DNA damage induced by styrene metabolism by bacterial CYP450cam (Ki = 204.2 μM)
Cayman Chemical 3-MethyladenIn 50mg
A specific inhibitor of PI3K activity and a widely used inhibitor of the autophagy; at 5 mM, inhibits protein degradation in rat hepatocytes by 65% and blocks class I, II, and III PI3Ks, including some downstream targets
Cayman Chemical PalmItoleoyl EthnolamIde 50mg
An N-acylethanolamine that is produced endogenously from palmitoleic acid