Sera
Cayman Chemical -GalocatechIn 100mg
A polyphenol and flavonoid that has diverse biological activities; inhibits adherence of P. gingivalis onto human buccal epithelial cells by >50% at 250 μg/ml; has antimutagenic properties in UV-irradiated E. coli cells; inhibits cell death induced by D-galactosamine and TNF-α in primary cultured mouse hepatocytes by 29.9% at 80 μM; inhibits HCT116 colorectal cancer cell proliferation by 57% at 100 μM
Cayman Chemical ParoxetInhydrochlorIde 50mg
A selective serotonin reuptake inhibitor (Ki = 0.04 nM); selective for SERT over the dopamine and norepinephrine transporters (Kis = 400 and 90 nM, respectively) as well as the 5-HT receptor subtypes 5-HT1A and 5-HT2A, the histamine H1 receptor, α1- and α2-ARs, and mAChRs (Kis = 21,168, 6,320, 13,746, 995, 3,915, and 42 nM, respectively); decreases immobility time in the forced swim test in mice at 5 mg/kg
Cayman Chemical nglca pubscns Subrosn 100mg
A prenylated coumarin with diverse biological activities; inhibits arachidonic acid-, collagen-, PAF-, ADP-, or U-46619-induced aggregation of washed isolated rabbit platelets (IC50s = 60, 132, 200, 234, and 200 µM, respectively); reduces arachidonic acid-induced TXB2 formation in the same model; inhibits PHA-induced NF-κB nuclear translocation in, as well as proliferation of, human PBMCs at 100 µM
Cayman Chemical Dihydrocapsaicin 50MG
A terpene alkaloid; active against a variety of bacteria and C. albicans (MICs = 0.6-10 UG/ml); scavenges DPPH and ABTS radicals in cell-free assays; increases LC3-II and catalase levels and reduces ROS production in normal WI38 lung fibroblasts and H1299, but not A549 or H460, lung cancer cells at 200 µM; a TRPV1 agonist; inhibits TPA-induced NETosis in isolated human neutrophils; induces cortical and systemic hypothermia and reduces infarct volume in a rat model of ischemia-reperfusion injury induced by MCAO at 0.5 mg/kg
Cayman Chemical Cotnn 50mg
An alkaloid and active metabolite of (±)-nicotine and (–)-nicotine; reduces the number of dsDNA breaks induced by NNK in a comet assay using HepaRG cells at 1 and 10 µM; increases nicotine self-administration in rats at 0.09 UG/kg
AdipoGen BioStab Peroxidase Conj Stabil
Horseradish peroxidase HRP is an enzyme commonly used for immunodetection. BioStab Peroxidase Conjugate Stabilizer extends the lifetime of HRP-antibody conjugates and increases the signal intensity, allowing much more consistent results over extended periods of time compared to daily prepared dilutions. BioStab Peroxidase Conjugate Stabilizer can be used in ELISA, Western Blotting, Immunohistochemistry and any other applications which require HRP conjugates. It is supplied as ready-to-use solution for dilution of HRP conjugates. This stabilizer contains a minimum amount of a surfactant and is free of any protein to minimize potential unspecific interactions.
Cayman Chemical O-desethyl DapaglIflozIn 50mg
An SGLT2 inhibitor (IC50 = 9.4 nM) and active metabolite of dapagliflozin; selective for SGLT2 over SGLT1 (IC50 = 970 nM)
Cayman Chemical 2-C-MethyladenosIn 50mg
An adenosine analog; inhibits HCV replication in vitro (IC50 = 0.3 µM); converted intracellularly to adenosine triphosphate; inhibits growth of L. guyanensis in vitro (EC50 = 3 µM); eradicates L. guyanensis in vitro (10 µM)
Cayman Chemical EVP-6124hydrochlorIde 50mg
A partial agonist of α7 subunit-containing nAChRs (IC50 = 22.38 nM); 1,000-fold selective for α7 subunit-containing nAChRs over α4β2 subunit-containing nAChRs at 10 µM, as well as a panel of 60 peptide and nonpeptide receptors, ion channels, and transporters; induces inward currents in Xenopus oocytes expressing human α7 subunit-containing nAChRs (EC50 = 0.16 µM); reverses scopolamine-induced deficits in the novel object recognition task and prevents natural forgetting of a familiar object in rats at 0.1, 0.3, and 1 mg/kg; reduces premature responding in the 5CSRTT in low-attentive female rats
Complement Technology Inc C5-Dpl Immuno Depleted Normal Human Serum, 1.0 mL vial, >50 mg protein/mL, Frozen liquid
C5-Dpl Immuno Depleted Normal Human Serum, 1.0 mL vial, >50 mg protein/mL, Frozen liquid
Cayman Chemical R S-natbIntartrate 50mg
A minor tobacco alkaloid; an agonist of α4β2 and α6/α3β2β4 subunit-containing nAChRs (EC50s = 6.1 and 3.6 µM, respectively); selective for these nAChRs over α3β4 subunit-containing nAChRs or α7 nAChRs (EC50s = 70.6 and 158.5 µM, respectively); stimulates dopamine release from isolated rat brain synaptosomes (EC50s = 1.76 and >100 µM, respectively); has anxiolytic-like activity in zebrafish at 10 mg/L; decreases disease severity in a mouse model of thyroglobulin, CFA, and M. tuberculosis immunization-induced moderate experimental autoimmune thyroiditis; decreases food and nicotine self-administration in monkeys (ED50s = 2.085 and 0.854 mg/kg, respectively); has been used as a biomarker of tobacco use
Cayman Chemical ThIoFluor 623 50mg
Reacts with thiols resulting in an increase in fluorescence intensity of up to 120-fold; the response is selective for thiols, occurs in aqueous media, and results in a fluorophore with emission at 623 nm; cell-permeable