Human Sera
Cayman Chemical 2hydroy MyrIsTC ACD mthy 50mg
An organochlorine antiseptic and antibacterial biocide active against S. aureus (MIC 1.56 g/ml) E. faecium isolates from fresh produce (MICs 5-50 mg/l) Salmonella isolates from meats (MICs 2.5-25 mg/l) and Pseudomonas isolates from slaughterhouse surfaces (MICs ≤0.0025-≤0.25 mg/l) inhibits infection of mouse astrocytoma DBT cells by recombinant MHV (IC50 1.2 M) inhibits recombinant human glutathione transferases P1-1 and A3-3 (IC50s 9.7 and v7 channels expressed in CHO cells (EC50 4.61 M) toxic to fasted and non-fasted rats (LD50s 215 and 165 mg/kg respectively) reduces R. solani-induced fruit rot in cucumber plants when applied at 4.4 kg/ha
Cayman Chemical 5 6-epoxy Cholestnol 50mg
A fluorescently tagged sphingolipid tagged with C12 NBD has been used to detect products of C12 NBD ceramide glycosylation
Cayman Chemical 1Oleoyl2hydroxysnglycero 50mg
A potent endocannabinoid uptake inhibitor (IC50s 10 and 283 nM for AEA and 2-AG respectively in U937 cells) inhibits AEA uptake in FAAH-deficient HMC-1 human mast cells and Neuro2a mouse neuroblastoma cells (IC50s 137 and 55 nM respectively) increases AEA and 2-AG levels by 1.5-fold in mouse brain but not peripheral tissues (10 mg/kg i.p. for seven days) induces a typical tetrad of hypothermia catalepsy analgesia and hypomotility in mice
Cayman Chemical AcetamIprId 100mg
A non-nucleoside reverse transcriptase inhibitor inhibits growth of wild-type (EC50 0.51 nM) and NNRTI-resistant HIV strains (EC50s 1 nM for L100I K103N V106A G190A and G190S mutants) reduces the plasma viral titer in HIV-1 infected humanized mice when used in combination with cabotegravir lamivudine and abcavir
Cayman Chemical 4NItrophenyl DXylopyrnos 100mg
An internal standard for the quantification of cystathionine by GC- or LC-MS
Cayman Chemical 5- 3-HydroxyphenylValero 100mg
A JAK3 inhibitor (IC50 11 UM) inhibits FcεRI-mediated LTC4 and LTB4 release from and 5-LO translocation to the membrane in RBL-2H3 mast cells at 10 UM reduces airway hyperresponsiveness and BALF eosinophil infiltration in a mouse model of ovalbumin-induced allergic asthma at 12 and 40 mg/kg
Cayman Chemical Propamocarb 100mg
An internal standard for the quantification of DL-phenylalanine by GC- or LC-MS
Cayman Chemical 2ImInobIotInhydrobromIde 100mg
A nucleotide sugar used by glycosyltransferases to glycosylate various substrates
Cayman Chemical N1 2 3DI 9octadecenoylox 50mg
A phenyl alkanoic acid with diverse biological activities active against A. flavus and A. ochraceus (MIC90s 7.5 mg/ml for both) active against various plant pathogenic fungi (MIC90s 3.75-7.5 mg/ml) improves egg laying production and eggshell strength in chickens at 0.3 w/w in the diet serum levels are lower in patients with benign MS compared with patients without MS patients with symptomatic MS and patients with MS resistant to fingolimod
Cayman Chemical FluorofenIdon 50mg
An active metabolite of ranolazine inhibits increases in T-wave height and the RR interval in a mouse model of isoprenaline-induced myocardial ischemia
Cayman Chemical PRfluoroheptnsulfonIc ACD 50mg
An ILK inhibitor (IC50 0.6 UM) inhibits the phosphorylation of Akt GSK3B and MLC in PC3 and MDA-MB-231 cells from 1-4 UM inhibits the proliferation of LNCaP PC3 MDA-MB-231 MDA-MB-468 SK-BR-3 and MCF-7 cancer cells (IC50s 1.6 2 1 1.5 1.8 and 2.5 UM respectively) induces autophagy and apoptosis in PC3 cells at 2 UM reduces protein levels of YB-1 HER2 and EGFR in PC3 cells reduces tumor growth in a PC3 mouse xenograft model at 25 and 50 mg/kg
Cayman Chemical PerfluorotrIdecnoIc AcId 100mg
A metabolite of isoleucine induces the formation of TBARS in isolated rat cerebral cortex at 0.5-5 mM elevated levels of are associated with 2-MBCDD also known as SBCAD
Cayman Chemical ParoxetInhydrochlorIde 100mg
A potent pan-Aurora kinase inhibitor that favors Aurora A (Ki 0.6 nM) over Aurora B (Ki 18 nM) or Aurora C (Ki 4.6 nM) inhibits proliferation of clear cell renal carcinoma (IC50 2/M phase