Human Sera
Cayman Chemical GInkgonlIc AcId 100mg
An anacardic acid with diverse biological activities; inhibits GPDH (IC50 = 3 μg/ml); inhibits PI3Kδ (IC50 = 2.49 μM) and IgE-mediated RBL-2H3 mast cell degranulation in vitro (IC50 = 2.4 μM); reduces S. mutans biofilm formation (MBIC50 = 4 μg/ml)
Cayman Chemical 9-EthylgunIn 50mg
A model nucleobase that is used to study DNA interactions with organometallic complexes, especially those designed to target tumors
Cayman Chemical Buparvaquon 50mg
An inhibitor of cytochrome bc1 in the parasites T. annulata and T. parva (in vitro EC50 of 1.5 x 10-8 M and 6.1 x 10-10 M, respectively)
Cayman Chemical ArgGlyAsptrIfluoroACTAte 50mg
A synthetic peptide corresponding to an integrin cell adhesion sequence; a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo
Cayman Chemical MIltefosIn 100mg
An inhibitor of CCT; inhibits liposome-induced CCT activity in MDCK cell homogenates from 10-50 µM, as well as induces translocation of CCT from the cell membrane to the cytosol in MDCK cells; inhibits PMA-induced phosphatidylcholine biosynthesis in MDCK and HeLa cells at 50 µM; inhibits phosphatidylserine-activated PKC (IC50 = 62 µM), as well as PMA-induced morphological changes and proliferation of MDCK cells; active against clinical isolate promastigotes of L. infantum (EC50s = 5-25 µM); topical application completely eradicates L. amazonensis and induces re-epithelialization of lesions in a mouse model of cutaneous leishmaniasis at 0.5%
American Research Products Inc Human lysophosphatidic acid L
Human lysophosphatidic acid (LPA) Elisa kit from CUSABIO Detection Range 3 9 ng/mL-250 ng/mL Sensitivity 3 9 ng/mL Sample serum plasma tissue homogenates Method Competitive
Cayman Chemical Velpatsvr 50mg
An NS5A inhibitor; inhibits replication of HCV genotypes 1-6 (EC50s = 6-130 pM in replicon assays); inhibits SARS-CoV-2 exonuclease activity at 100 µM; enhances remdesivir-induced inhibition of SARS-CoV-2 replication in infected Calu-3 cells at 10 µM
Cayman Chemical 6 7 4TrIhydroxyIsoflavon 100mg
An active metabolite of daidzein; suppresses anchorage-dependent and -independent growth of HCT116 and DLD-1 colon cancer cells, as well as induces cell cycle arrest at the S and G2/M phases in HCT116 cells from 12.5-100 µM; inhibits MDI-induced adipogenesis in 3T3-L1 preadipocytes at 40 and 80 µM; reverses scopolamine-induced memory impairments and increases hippocampal BDNF and CREB levels in mice at 5 mg/kg; prevents LPS-induced bone loss in mice
Cayman Chemical StachydrInhydrochlorIde 100mg
A pyrrolidine betaine with potent anti-metastatic and cardioprotective effects
Cayman Chemical IrsogladInmaleate 50mg
A gastroprotective agent; increases transfer of Lucifer yellow CH between isolated rabbit gastric epithelial cells, indicating enhanced GJIC; inhibits gastric mucosal lesion formation and decreases in gastric mucosal blood flow induced by monochloramine in rats at 3 mg/kg, effects that can be prevented by L-NAME; inhibits fMLP-induced superoxide anion production and increases cAMP levels in isolated human neutrophils in a concentration-dependent manner, similar to rolipram
Cayman Chemical LevobetaxololhydrochLRIde 50mg
A β1-adrenergic receptor antagonist (Ki = 0.76 nM for the human receptor); selective for β1-ARs over β2-ARs (Ki = 32.6 nM), as well as a panel of 89 additional receptors (IC50s = >1 µM); inhibits isoproterenol-induced cAMP production in human non-pigmented ciliary epithelial cells (Ki = 16.4 nM); topical application reduces intraocular pressure in a cynomolgus monkey model of ocular hypertension at 150 UG/eye
Cayman Chemical 2AmInopurInhydrochLRIde 100mg
A fluorescent analog of guanosine and adenosine that is used as a site-specific probe of nucleic acid structure and dynamics, such as studies of base stacking interactions and DNA base flipping; ex/em = 320/381 nm, respectively, when adjusted to reduce interference with DNA base absorption as well as tryptophan fluorescence; inhibits PKR
Cayman Chemical DLCystathIonInhydroCLOrI 100mg
An intermediate in the synthesis of cysteine that is produced from homocysteine and serine by the action of cystathionine-β-synthase; excess cystathionine in the urine is a hallmark of cystathioninuria
Cayman Chemical HmAhydrochlorIde 50mg
An analytical reference standard categorized as an amphetamine; an active metabolite of 3,4-MDMA; intended for research and forensic applications
Cayman Chemical 4ndrosten11ol3 17dIon 50mg
A non-androgenic steroid; metabolized to various androgenic 5α-reduced C19 steroids in LNCaP cells