Human Sera
Cayman Chemical ErgoloIdmesylates 50mg
An internal standard for the quantification of melatonin by GC- or LC-MS
Cayman Chemical ChlorntrnIlIprole 50mg
An active metabolite of sunitinib formed when sunitinib undergoes N-de-ethylation by CYP3A4 is pharmacologically active having similar inhibitory activity to sunitinib
Cayman Chemical Hexaconazole 100mg
A non-competitive inhibitor of guanylyl and adenylyl cyclases suppresses STa- guanylin- atrial natriuretic peptide- and C-type natriuretic peptide-induced cGMP accumulation in cells (IC50s 3.4-11.2 M) inhibits STa- forskolin- cholera toxin- and isoproterenol-induced chloride efflux in T84 cells suppresses STa-induced liquid secretion in a rabbit intestinal loop model of toxin-induced secretory diarrhea (10 or 50 M)
Cayman Chemical Flumethason 100mg
An a7-containing nAChR agonist activates human a7-containing nAChRs to 60 of the levels generated by endogenous ligand acetylcholine has no activity at a2- a3- and a4-containing nAChRs at a concentration of 100 M stimulates dopamine release from rat striatal slices (EC50 10 M) decreases delay in the delayed matching-to-sample task in monkeys suppresses amnesia and neuronal cell death in a gerbil model of ischemia-reperfusion injury
Cayman Chemical SpIromesIfen 100mg
A photosensitizer active against S. aureus P. aeruginosa E. coli and S. typhimurium when used at 20 UM in combination with PDT induces tumor regression when combined with PDT in several sarcoma rat xenograft models at 5 and 10 mg/kg
Cayman Chemical Terconazole 100mg
A CEPT inhibitor (IC50s 17 and 15 nM for CETP-dependent transfer of cholesterol esters and triglycerides respectively) decreases plasma levels of LDL and triglycerides reduces atherosclerotic lesion sizes and increases HDL levels in the E3L.CETP mouse model of atherosclerosis increases HDL levels by 2-fold and lowers LDL and fasting plasma triglyceride levels in rhesus macaques at 150 mg/kg
Cayman Chemical IsoquercetIn 100mg
A fluorometric probe that acts as a substrate for ALDH1A1 esterase activity and chymotrypsin
Cayman Chemical CefmenoxImehydrochlorIde 100mg
An imidazole antifungal agent completely inhibits growth of a variety of fungi in vitro when used at concentrations of 0.05-30 Ug/ml active against vaginal infections of C. albicans in mice when used vaginally at concentrations of 0.25-2 and 0.1-1 respectively
Cayman Chemical ArtemIsInIc AcId 100mg
An internal standard for the quantification of ethyl-b-D-glucuronide by GC- or LC-MS
Cayman Chemical ACtyl TetrapeptID9ACTAt 100mg
8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish 479557
Cayman Chemical LEE011succInate 100mg
An internal standard for the quantification of methimazole by GC- or LC-MS
Cayman Chemical 3amInoLTyrosInhydrochlo 50mg
5(R)-HETE is a rare lipoxygenase product of arachidonic acid Nearly all plant and animal 5-LOs produce 5(S)-HETE but the presence of a 5(R)-LO and the synthesis of 5(R)-HpETE and 5(R)-HETE have been confirmed in oocytes of the bivalve mollusk S solidissima 4720 5(R)-HETE is more potent than the (S)-enantiomer as a chemotactic agent for human neutrophils 2651
Cayman Chemical HomobrasInolIde 50mg
A fungal metabolite active against S aureus (MIC 52 4 UM) inhibits the growth of L5178Y mouse lymphoma cells (IC50 0 1 Ug/ml) inhibits LPS-induced NO production in RAW 264 7 cells (IC50 5 48 UM)
