Human Sera
Cayman Chemical D-NmAacetate 100mg
The inactive enantiomer of L-NMMA used as a control compound to explore non-specific effects of L-NMMA
Cayman Chemical RPramIpexolehydrochLRId 50mg
An enantiomer of pramipexole that is ~100-fold less active than the (S) form as a dopamine receptor agonist; an antioxidant that targets mitochondria to prevent apoptosis
Cayman Chemical In vItro Screeng for DrugI 96
A RIPK1 inhibitor (IC50s 16 and 2500 nM for the human and mouse enzymes respectively) 10000-fold selective for RIPK1 over a panel of 339 kinases at 10 UM inhibits necrotic cell death induced by a combination of TNF-a and the caspase inhibitor QVD-OPh in U937 human monocytic and L929 murine fibrosarcoma cells (IC50s 6 3 and 1300 nM respectively) decreases IL-1B and IL-6 levels in intestinal mucosa tissue isolated from patients with ulcerative colitis at 3-300 nM increases survival in a mouse model of TNF-a-induced lethal shock at 3 10 and 50 mg/kg
Cayman Chemical Fenvalerate 50mg
A pyrethroid insecticide and acaricide; a slow activator of Nav1.8; induces mortality of pyrethroid-susceptible and -resistant strains in M. domestica (LD50s = 0.014-5 UG/fly); induces mortality in tobacco budworm larvae but is associated with pyrethroid resistance with an increase in LD50 values from 1.01 to 20.85 UG/g over a six-year timeframe; induces mortality in 95.5% of T. macfarlanei spider mites at 0.015%
Cayman Chemical DInItolmIde 50mg
An anticoccidial agent; dietary administration reduces mortality and decreases the number of oocysts and oocyst sporulation in chick models of E. maxima, E. brunetti, or E. acervulina infection from 125-500 ppm
Miltenyi Biotec, Inc. BASOPHIL ISO KIT HUMAN
5000256658 BASOPHIL ISO KIT HUMAN
Cayman Chemical MoguIsteIn 100mg
A peripherally acting antitussive agent; inhibits the citric acid-induced cough reflex in conscious guinea pigs but not the cough reflex induced by electrical stimulation of the afferent superior laryngeal nerve in anesthetized guinea pigs (ED50s = 5.5 and >20 mg/kg, respectively); prevents BALF eosinophil and neutrophil infiltration in an ovalbumin-sensitized guinea pig model of allergic airway inflammation; inhibits increases in tracheal and bronchial plasma exudation induced by cigarette smoke in anesthetized guinea pigs at 30 mg/kg
Cayman Chemical NSuccInImIdylSACtylthIoac 50mg
A protein-modifying agent; introduces sulfhydryl groups to proteins; used in conjunction with the protein cross-linking reagent SMCC in the conjugation of proteins with IgG antibodies for use in ELISAs