Serum Substitutes
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN NAGLU KNOCKOUT CELL LINE
NC2455731 HUMAN NAGLU KNOCKOUT CELL LINE
Biolegend Spark UVTM 387 anti-mouse IFN-
Spark UV™ 387 anti-mouse IFN-γ [XMG1.2]; Isotype: Rat IgG1, κ; Reactivity: Mouse; Apps: ICFC; Size: 25 μg
Biolegend Brilliant Violet 711TM anti-hu
Brilliant Violet 711™ anti-human IFN-γ [B27]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC; Size: 100 tests
Biolegend Spark NIRTM 685 anti-mouse IFN
Spark NIR™ 685 anti-mouse IFN-γ [XMG1.2]; Isotype: Rat IgG1, κ; Reactivity: Mouse; Apps: ICFC; Size: 25 μg
Biolegend Brilliant Violet 711TM anti-hu
Brilliant Violet 711™ anti-human IFN-γ [B27]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC; Size: 25 tests
Cayman Chemical SR 95531hydrobromIde 5mg
Induces neuronal differentiation in skeletal muscle cells as indicated by the upregulated expression of neuron-specific markers effective with mature muscle fibers as well as myoblasts
Cayman Chemical SR 59230AhydrochlorIde 5mg
A bivalent BRD4 inhibitor (IC50 5 nM) that simultaneously binds two bromodomains in BRD4 demonstrates antitumor activity in multiple xenograft models of acute myeloid leukemia multiple myeloma and diffuse large B cell lymphoma
Cayman Chemical sR 128129E 10mg
An orally bioavailable inhibitor of sEH (IC50 0 33 UM) and agonist of PPARY (EC50 of 0 3 UM) water soluble orally bioavailable and can be delivered through drinking water to upregulate PPARY target genes
Cayman Chemical SR 717lIthIum salt 25mg
A CK1 inhibitor (Ki 8 5 M) elective for CK1 over CK2 PKC CaMKII and cyclic AMP-dependent protein kinase (IC50s 90 1000 195 and 550 M respectively) inhibits phosphorylation of a peptide substrate by Leishmania CK1 2 at 10 M
Cayman Chemical SR 717lIthIum salt 50mg
A CK1 inhibitor (Ki 8 5 M) elective for CK1 over CK2 PKC CaMKII and cyclic AMP-dependent protein kinase (IC50s 90 1000 195 and 550 M respectively) inhibits phosphorylation of a peptide substrate by Leishmania CK1 2 at 10 M
Cayman Chemical SR 59230AhydrochlorIde 10mg
An iron chelator with antiproliferative effects inhibits in vitro proliferation of SK-N-MC neuroepithelioma SK-Mel-28 melanoma and MCF-7 breast cancer cells (IC50s 30 60 and 60 nM respectively) increases mobilization of 59Fe from SK-N-MC cells and M109 mouse lung carcinoma cells (25 and 1 UM respectively) enhances cytotoxicity in several multidrug resistant human cancer cell lines following transport to lysosomes by P-glycoprotein inhibits M109 tumor growth in mice reducing tumor weight to 47 of control values (0 4 mg/kg) reduces tumor size and weight in an oral squamous cell carcinoma mouse xenograft model (0 5 mg/kg)
Cayman Chemical sR 128129E 25mg
A VEGFR inhibitor (IC50s 0 82 0 037 and 0 42 UM for hVEGFR1 2 and 3 respectively) also inhibits Tie2 and RET with IC50 values of 0 65 and 0 41 respectively reduces inflammation in a mouse model of psoriasis and in pig models of contact hypersensitivity and UV-B-induced erythema
Cayman Chemical SR 95531hydrobromIde 25mg
A form of the 14-carbon myristic acid with an ω-terminal alkyne group can be used in linking reactions utilizing click chemistry