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Filtered Search Results
ABclonal Technology FGL2 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
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Medchemexpress LLC TRAP1 Human GST 50ug
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Recombinant human TRAP1 protein comprising amino acids S60-E308 is supplied as an N-terminal GST-tagged fragment expressed in Escherichia coli. The lyophilized preparation is formulated from PBS with 6% trehalose (pH 7.4), has an apparent molecular weight of ~54.5 kDa, and is ≥90% pure by reducing SDS-PAGE. Store at -20°C; after reconstitution, store at 4°C for up to one week or -20°C for extended storage and avoid repeated freeze-thaw cycles.
- Recombinant fragment spans S60-E308, representing the TRAP1 functional region.
- N-terminal GST tag enables affinity purification and detection.
- Expressed in Escherichia coli for bacterial expression yield.
- Lyophilized formulation with trehalose enhances long-term stability.
- High purity (≥90%) suitable for biochemical assays.
- Recommended storage conditions minimize degradation after reconstitution.
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Human CFHR2 ELISA Pair Set 5PP (Sino Biological)
Each vial contains 25 ng of recombinant Human CFHR2. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 600 pg/mL is recommended.
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ABclonal Technology [KD Validated] NF2 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this proteins function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities.
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ABclonal Technology STOML2 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Enables GTPase binding activity and cardiolipin binding activity. Involved in several processes, including inorganic cation transmembrane transport, positive regulation of cardiolipin metabolic process, and positive regulation of mitochondrial DNA replication. Located in membrane raft, mitochondrial inner membrane, and mitochondrial intermembrane space. Is extrinsic component of plasma membrane. Colocalizes with several cellular components, including COP9 signalosome, T cell receptor complex, and immunological synapse.
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Biotium Thymidylate Synthase (5-FU Resistance Marker)(rTYMS/1884), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2. 1. 1. 45). It converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5, 10-methylenetetrahydrofolate. Expression of TS protein has been reported to associate with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommende
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Biotium S100A9(S100A9/1075), 1mg/mL
This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylate
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ACROBiosystems AAV Capsid Titration Detection Antibody Pair (Universal)
Adeno-associated virus (AAV) is the simplest and non-enveloped single-stranded DNA virus with a viral genome length of about 4.7Kb, which belongs to the parvovirus family. AAV has become one of the most important gene vectors in the field of gene therapy due to its long-term expression, low toxicity, low immunogenicity, and high tissue specificity.
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Biotium Granzyme B (NK/T-Cell Lymphoma Marker)(GZMB/3014), 0.2mg/mL
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommende
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ABclonal Technology PROS1 Rabbit pAb
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
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Human CFHR2 ELISA Pair Set 15PP (Sino Biological)
Each vial contains 25 ng of recombinant Human CFHR2. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 600 pg/mL is recommended.
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Sino Biological Anti-Cathepsin D Antibody, Rabbit Polyclonal 100 µL
Produced in rabbits immunized with purified, recombinant Human Cathepsin D (rh Cathepsin D; Catalog#12517-H08H; P07339; Met1-Leu412). Cathepsin D specific IgG was purified by Human Cathepsin D affinity chromatography.
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ABclonal Technology TAF6L Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a protein that is part of the PCAF histone acetylase complex, which plays a key role in myogenic transcription and differentiation. The protein is structurally similar to TAF6, a histone-like component of the TFIID complex. TFIID coordinates RNA polymerase II transcription by binding to the core promoter and assembling the transcription complex. TFIID consists of the TATA-binding protein (TBP) and TBP-associated factors (TAFs), which aid in basal transcription, promoter recognition, and transcription initiation. The PCAF complex, made up of over 20 polypeptides, including TAFs, is essential for gene regulation during differentiation.
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Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(CPTC-ANXA1-1), CF647 conjugate, 0.1mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluo
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Miltenyi Biotec, Inc. CD55 (DAF)-FITC, human, JS11, 30 tests
Identification and enumeration of CD55 (DAF)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services