Primary Antibody Matched Pairs
Sino Biological Recombinant Human AKT2 Protein (Full length, TST & Trx & TEV Tag) 10
Recombinant full-length human AKT2 was expressed by baculovirus in Sf9 insect cells using an N-terminal TST-Trx-TEV tag.
Biotium CD79b (B-Cell Marker)(IGB/3170R), CF405S conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(6E4/3), 0.2mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluo
ABclonal Technology AGTRAP Rabbit pAb
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
Apexbio Technology LLC REC MU LCN2 HIS-1mg
Recombinant Mouse Lipocalin-2 (His) is a protein used in biomedical research focusing on molecular biology and inflammation pathways Originating from mouse models it primarily targets iron transport mechanisms influencing immune response and cell signaling pathways In vitro its activity is often observed in the nanomolar to low micromolar range Typical applications include studies involving cell models animal experiments and drug screening to assess its role in inflammatory conditions and iron metabolism Experimental concentrations typically depend on the specific research design ensuring adaptability across diverse study requirements
Biotium HIF1 alpha (Hypoxia-Inducible Factor 1-alpha)(ESEE122), CF568 conjugate, 0.1mg/mL
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc. ) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains sta
Sino Biological Protein LCN2 ET-FREE 100UG
A DNA sequence encoding the human Lipocalin 2 precursor (NP 005555 2) (Met 1-Gly 198) was expressed with a C-terminal polyhistidine tag
Sino Biological Protein NCAM1 ET-FREE 100UG
A DNA sequence encoding the human NCAM1 (NP 001070150 1) (Met1-Pro603) was expressed with a polyhistidine tag at the C-terminus
Sino Biological Anti-IL-1 alpha/IL1A Antibody, Rabbit Polyclonal 100
Produced in rabbits immunized with purified, recombinant Human IL-1 alpha/IL1A (rh IL-1 alpha/IL1A; Catalog#10128-HNCH; NP_000566.3; Ser113-Ala271). IL-1 alpha/IL1A specific IgG was purified by Human IL-1 alpha/IL1A affinity chromatography.
Bioss KD-Validated ATP1B3 Rabbit Rec
ATPase Na /K Transporting Subunit Beta 3 Primary Antibody Unconjugated Public Immunogen Range 241-279/279 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Biotium CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/1781), CF594 conjugate, 0.1mg/mL
DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF
Sino Biological Recombinant Human EPCR Protein (His Tag), Biotinylated, HPLC-verified 20 µg
A DNA sequence encoding the extracellular domain of human PROCR (Q9UNN8) (Met 1-Thr 209), was fused with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro.
Sino Biological Recombinant Human NCAM-1/CD56 Protein (Site-Specific PE Conjugation, His Tag) 100 Tests
A DNA sequence encoding the human NCAM1 (NP_001070150.1) (Met 1-Pro 603) was expressed with a C-terminal polyhistidine tag. The protein is site-specifically conjugated with PE (Excitation= 495 - 566 nm, Emission Max.= 575 nm).
Biotium MALT1 (MALT-Lymphoma Marker)(rMT1/410), CF740 conjugate, 0.1mg/mL
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not r
ABclonal Technology TKT/Transketolase
This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene