Primary Antibody Matched Pairs
Sino Biological Recombinant Human CTLA-4 Protein (APC site-specific conjugation, His Tag) 100
A DNA sequence encoding the human CTLA4 (NP005205.2) (Lys36-Phe162) was expressed with a C-terminal polyhistidine tag. The protein is site-specifically conjugated with APC (Excitation Max.= 651 nm, Emission Max.= 662 nm).
iQ Biosciences Purified Human B Cells, 5M cells/vial
High-quality, high-viability (> 90%) human B cells purified from PBMCs of healthy blood donors sourced from a world-renowned blood center. Highly enriched (> 90%) post-selection purity achieved via magnetic isolation. All orders come with an iQ Certificate of Analysis.
HIV Gag-p24 ELISA Pair Set 15PP (Sino Biological)
Each vial contains 24 ng of recombinant Human Immunodeficiency Virus type 1 (HIV-1) p24 / Capsid Protein p24. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 1200 pg/mL is recommended.
Biotium CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) (NCAM1/1496), CF405S conjugate, 0.1mg/mL
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not
Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker)(PRF1/2467), 1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjug
Genscript Corporation CD27 Ligand/CD70 Fc Chimera H
CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene CD70 is a ligand for CD27 The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity in particular during antiviral responses Upon CD27 binding induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells The CD70 protein is expressed on highly activated lymphocytes (like in T- and B-cell lymphomas) It is therefore suggested that anti-CD70 antibodies might be a possible treatment for CD70 positive lymphomas as normal lymphocytes have low CD70 expression
ABclonal Technology CD96 Rabbit mAb
CD96 (cluster of differentiation 96) belongs to the IgG (immunoglobulin) superfamily receptors It is expressed in the spinal cord kidney trachea digestive tissues prostate placenta bone of adults and fetal brain and liver This gene is located on human chromosome 3q13 The protein encoded by this gene belongs to the immunoglobulin superfamily It is a type I membrane protein The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response It may also function in antigen presentation Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified
Biotium PLAP (Placental Alkaline Phosphatase)(ALPP/238), CF740 conjugate, 0.1mg/mL
PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2 metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conju
Human VSIG4 ELISA Pair Set 15PP (Sino Biological)
Each vial contains 100 ng of recombinant VSIG4. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 2 ng/mL is recommended.
Biotium RAD51 (Prognostic and Response to Chemotherapy Marker)(RAD51/2753), CF740 conjugate, 0.1mg/mL
RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancies. RAD51 overexpression correlates with histological grading of the tumor in invasive ductal mammary carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightnes
Biotium Human Kappa Light Chain (B-Cell Marker) (IGKC/1999R), CF405S conjugate, 0.1mg/mL
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give h
Human SELE ELISA Pair Set 15PP (Sino Biological)
Each vial contains 135 ng of recombinant Human E-Selectin / CD62e / SELE. Reconstitute with 1 mL dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 6000 pg/mL is recommended.