Goat Secondary Antibodies
ABclonal Technology POLR2H Rabbit pAb
The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene.
American Research Products Inc AntiMouse TNFalpha In Vivo Ab
Anti-Mouse TNFalpha In Vivo Antibody - Low Endotoxin is a in vivo antibody with mouse reactivity produced in armenian hamster Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
Abcam Goat Anti-Mouse IgG H&L (DyLight 594).
Goat Anti-Mouse IgG H&L (DyLight 594).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Goat Anti-Mouse IgG Fc (DyLight 594) preadsorbed.
Goat Anti-Mouse IgG Fc (DyLight 594) preadsorbed.
The product is subject to the following: Abcam Restricted Use Statement
Jackson Immuno Research Labs Biotin-SP (long spacer) AffiniPure F(ab')₂ Fragment Goat Anti-Mouse IgG, Fcγ fragment specific, .5ml
Biotin-SP-AffiniPure F(ab')2 Fragment Goat Anti-Mouse IgG, FcY Fragment Specific (min X Hu,Bov,Hrs Sr Prot)
Cayman Chemical Catlase asy KItwIthout H 96Wel
A multi-kinase inhibitor inhibits FLT3 CSF1R c-Kit FGFR1 FGFR3 VEGFR1 -2 and -3 PDFGRa and PDGFRB (IC50s 1 36 2 8 9 10 13 8 27 and 210 nM respectively) inhibits the proliferation of human multiple myeloma cell lines expressing mutant but not wild-type FGFR3 (IC50s 90-550 and >2500 nM respectively) decreases FGF-induced ERK1/2 phosphorylation and induces apoptosis in patient-derived multiple myeloma cells at 500 nM inhibits bFGF-induced angiogenesis in a Matrigel™ plUG assay in mice at 3-300 mg/kg for 8 days reduces tumor growth in KM12L4A DU145 and MV4-11 mouse xenograft models (ED50s 17 23 and 3 mg/kg per day respectively)
Revvity Health Sciences Inc PhenoVue Fluor 568 - Goat Anti-Mouse Antibody Highly Cross-Adsorbed
PhenoVue Fluor 568 - Goat Anti-Mouse Antibody Highly Cross-Adsorbed
KRISHGEN BIOSYSTEMS Immunoassay for the quantitative Determination of Anti-Ustekinumab antibodies in human serum and plasma. Assay Range: 10 - 640 ng/ml; Sensitivity: 5ng/ml.
Pack Size: 1 x 96 wells. This ELISA is optimised to detect antibodies to ustekinumab in human samples and may be used for immunogenicity monitoring. If you would like to use animal samples, please contact us. Introduction: Ustekinumab is a human monoclonal antibody. It is directed against interleukin 12and interleukin 23, naturally occurring proteins that regulate the immune system and immune-mediated inflammatory disorders. Ustekinumab is approved in Canada, Europe and the United States to treat moderate to severe plaque psoriasis. ADA has been observed in preclinical and clinical studies, resulting in significant changes in toxicology, pharmacokinetics and efficacy. These effects result from the generation of drug-induced (neutralizing) autoantibodies against Etanercept and can be responsible for allergic reaction, or even anaphylactic shock. ELISA Features include a pre-coated plate with break-apart wells, standardisation and Precision CV <10%.
ABclonal Technology STXBP2 Rabbit pAb
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
ABclonal Technology CAPN9 Rabbit pAb
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology MFGE8 Rabbit pAb
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
ABclonal Technology GLE1 Rabbit pAb
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology IFT74 Rabbit pAb
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
Abcam Goat Anti-Mouse IgE (Heavy chain)
Goat Anti-Mouse IgE (Heavy chain)
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical S-Glycyl-H-1152hydrochlor 5mg
A selective and potent ROCK inhibitor (IC50 = 11.8 nM for ROCK2); poorly inhibits CaMKII, PKG, and Aurora A (IC50 = 2.57, 2.35, and 3.26 μM, respectively) as well as PKA or PKC (IC50 ≥10 μM for EAch)