Hamster Secondary Antibodies
ICOS (CD278) Armenian Hamster anti-Human, Mouse, Alexa Fluor™ 488, Clone: C398.4A, BD Phrmingen™
Armenian Hamster Monoclonal Antibody
American Research Products Inc Anti CD152 CTLA4 ADG 126
Anti-Human CD152/CTLA4 (ADG 126) Research Grade
Selleck Chemical LLC Tremelimumab-A2021-1MG
Tremelimumab (Ticilimumab CP-675 206) is a fully human monoclonal antibody that binds to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) on the surface of activated T lymphocytes
ABclonal Technology 450 anti-Human CD152/CTLA-4
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells The protein contains a V domain a transmembrane domain and a cytoplasmic tail Alternate transcriptional splice variants encoding different isoforms have been characterized The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond while the soluble isoform functions as a monomer Mutations in this gene have been associated with insulin-dependent diabetes mellitus Graves disease Hashimoto thyroiditis celiac disease systemic lupus erythematosus thyroid-associated orbitopathy and other autoimmune diseases
ABclonal Technology ABflo 594 Rabbit anti- CD28
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
ABclonal Technology ABflo 488 Rabbit anti- CD28
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
ABclonal Technology 450 anti-Human CD152/CTLA-4
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells The protein contains a V domain a transmembrane domain and a cytoplasmic tail Alternate transcriptional splice variants encoding different isoforms have been characterized The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond while the soluble isoform functions as a monomer Mutations in this gene have been associated with insulin-dependent diabetes mellitus Graves disease Hashimoto thyroiditis celiac disease systemic lupus erythematosus thyroid-associated orbitopathy and other autoimmune diseases
ABclonal Technology PE Rabbit anti- CD152/CTLA-4
CD152 also known as CTLA-4 or Ly-56 is a 33 kDa member of the immunoglobulin superfamily It is expressed on activated T and B lymphocytes CD152 exhibits significant homology to CD28 in amino acid sequence structural configuration and genomic organization with both receptors sharing ligands from the B7 family (B7-1 and B7-2) While CD28 delivers co-stimulatory signals during T cell activation CTLA-4 functions as a critical negative regulator of cell-mediated immune responses CD152 is implicated in the induction and maintenance of immune tolerance the development of protective immunity and the modulation of thymocyte homeostasis
ABclonal Technology APC Rabbit anti-Human CD28 mAb
The protein encoded by this gene is essential for T-cell proliferation and survival cytokine production and T-helper type-2 development Several alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology APC Rabbit anti-Human CD28 mAb
The protein encoded by this gene is essential for T-cell proliferation and survival cytokine production and T-helper type-2 development Several alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Mouse CD28 mAb
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD28 mAb
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
ABclonal Technology PE Rabbit anti-Human CD28 mAb
The protein encoded by this gene is essential for T-cell proliferation and survival cytokine production and T-helper type-2 development Several alternatively spliced transcript variants encoding different isoforms have been found for this gene