Hamster Secondary Antibodies
Invitrogen™ CTLA-4 Recombinant Rabbit Monoclonal Antibody (R3P1-E11)
Rabbit Recombinant Monoclonal Antibody
ICOS (CD278) Armenian Hamster anti-Human, Mouse, Alexa Fluor™ 488, Clone: C398.4A, BD Phrmingen™
Armenian Hamster Monoclonal Antibody
RB670 Hamster Anti-Mouse CD28, BD OptiBuild™
Hamster Monoclonal Secondary Antibody
Invitrogen™ CTLA-4 Recombinant Human Monoclonal Antibody (12E8)
Human Recombinant Monoclonal Antibody
RY703 Hamster Anti-Mouse CD28, BD OptiBuild™
Hamster Monoclonal Secondary Antibody
Biotium CD28(C28/74), CF740 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Selleck Chemical LLC Tremelimumab-A2021-1MG
Tremelimumab (Ticilimumab CP-675 206) is a fully human monoclonal antibody that binds to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) on the surface of activated T lymphocytes
AdipoGen CD152 hrecuntagged
Recombinant protein. Human CD152 aa 36-161 is untagged. Binds to human CD80. Source HEK 293 cells. Lyophilized. Contains PBS. CD152 Cytotoxic T-lymphocyte-associated protein 4 CTLA-4 is an inhibitory receptor belonging to the CD28 immunoglobulin subfamily, expressed primarily by T cells. Its ligands, CD80 and CD86, are typically found on the surface of antigen-presenting cells and can either bind CD28 or CTLA-4, resulting in a costimulatory or a co-inhibitory response, respectively. Because of its dampening effect, CTLA-4 is a crucial regulator of T cell homeostasis and self-tolerance. While CD28 promotes T cell activation and proliferation, CTLA-4 is reported to dampen T cell responses through a variety of mechanisms. Prior to activation, conventional T cells Tconv express low levels of CTLA-4, predominantly in intracellular compartments. Upon activation, CTLA-4 expression is upregulated and becomes increasingly detectable on the cell surface.
American Research Products Inc AntiMouse CD28 In Vivo Ab
Anti-Mouse CD28 In Vivo Antibody - Ultra Low Endotoxin is a in vivo antibody with mouse reactivity produced in syrian hamster Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
American Research Products Inc AntiMouse CD28 In Vivo Ab
Anti-Mouse CD28 In Vivo Antibody - Low Endotoxin is a in vivo antibody with mouse reactivity produced in syrian hamster Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
ABclonal Technology PE anti-Human CD152/CTLA-4
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells The protein contains a V domain a transmembrane domain and a cytoplasmic tail Alternate transcriptional splice variants encoding different isoforms have been characterized The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond while the soluble isoform functions as a monomer Mutations in this gene have been associated with insulin-dependent diabetes mellitus Graves disease Hashimoto thyroiditis celiac disease systemic lupus erythematosus thyroid-associated orbitopathy and other autoimmune diseases
Biotium CD28 (C28/1636), CF568 conjugate, 0.1mg/mL
This antibody recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.