Hamster Secondary Antibodies
Invitrogen™ CTLA-4 Recombinant Rabbit Monoclonal Antibody (R3P1-E11)
Rabbit Recombinant Monoclonal Antibody
RB670 Hamster Anti-Mouse CD28, BD OptiBuild™
Hamster Monoclonal Secondary Antibody
ICOS (CD278) Armenian Hamster anti-Human, Mouse, Alexa Fluor™ 488, Clone: C398.4A, BD Phrmingen™
Armenian Hamster Monoclonal Antibody
Invitrogen™ CTLA-4 Recombinant Human Monoclonal Antibody (12E8)
Human Recombinant Monoclonal Antibody
RY703 Hamster Anti-Mouse CD28, BD OptiBuild™
Hamster Monoclonal Secondary Antibody
Biotium CTLA4 / CD152 (Negative Regulator of T-Cells)(L4P2F5.F10), CF594 conjugate, 0.1mg/mL
CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer excepti
ABclonal Technology PE Rabbit anti- CD152/CTLA-4
CD152 also known as CTLA-4 or Ly-56 is a 33 kDa member of the immunoglobulin superfamily It is expressed on activated T and B lymphocytes CD152 exhibits significant homology to CD28 in amino acid sequence structural configuration and genomic organization with both receptors sharing ligands from the B7 family (B7-1 and B7-2) While CD28 delivers co-stimulatory signals during T cell activation CTLA-4 functions as a critical negative regulator of cell-mediated immune responses CD152 is implicated in the induction and maintenance of immune tolerance the development of protective immunity and the modulation of thymocyte homeostasis
American Research Products Inc AntiMouse CD28 In Vivo Ab
Anti-Mouse CD28 In Vivo Antibody - Low Endotoxin is a in vivo antibody with mouse reactivity produced in syrian hamster Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
Biotium CTLA4 / CD152 (Negative Regulator of T-Cells)(L4P2F5.F10), CF488A conjugate, 0.1mg/mL
CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer excepti
Biotium CTLA4 / CD152 (Negative Regulator of T-Cells)(L4P2F5.F10), CF405S conjugate, 0.1mg/mL
CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer excepti
Cytek Biosciences Inc APC aMu CD152 Anti Primary
Product Name: APC Anti-Mouse CD152 (CTLA-4) (UC10-4F10-11)
Product Class: Antibody
Type: Primary
Product Name: APC Anti-Mouse CD152 (CTLA-4) (UC10-4F10-11)
Cytek Catalog Number: 20-1522-U025
Marker: CD152 (CTLA-4)
Target Species: Mouse
Clonality: Monoclonal
Clone: UC10-4F10-11
Host Species: Armenian Hamster
Isotype: IgG
Conjugation: APC
Size: 25 μg
ABclonal Technology PE anti-Human CD152/CTLA-4
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells The protein contains a V domain a transmembrane domain and a cytoplasmic tail Alternate transcriptional splice variants encoding different isoforms have been characterized The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond while the soluble isoform functions as a monomer Mutations in this gene have been associated with insulin-dependent diabetes mellitus Graves disease Hashimoto thyroiditis celiac disease systemic lupus erythematosus thyroid-associated orbitopathy and other autoimmune diseases
Biotium CTLA4 / CD152 (Negative Regulator of T-Cells)(L4P2F5.F10), CF488A conjugate, 0.1mg/mL
CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer excepti
AdipoGen CD152 hrecuntagged
Recombinant protein. Human CD152 aa 36-161 is untagged. Binds to human CD80. Source HEK 293 cells. Lyophilized. Contains PBS. CD152 Cytotoxic T-lymphocyte-associated protein 4 CTLA-4 is an inhibitory receptor belonging to the CD28 immunoglobulin subfamily, expressed primarily by T cells. Its ligands, CD80 and CD86, are typically found on the surface of antigen-presenting cells and can either bind CD28 or CTLA-4, resulting in a costimulatory or a co-inhibitory response, respectively. Because of its dampening effect, CTLA-4 is a crucial regulator of T cell homeostasis and self-tolerance. While CD28 promotes T cell activation and proliferation, CTLA-4 is reported to dampen T cell responses through a variety of mechanisms. Prior to activation, conventional T cells Tconv express low levels of CTLA-4, predominantly in intracellular compartments. Upon activation, CTLA-4 expression is upregulated and becomes increasingly detectable on the cell surface.
Medchemexpress LLC CD28 Rat HEK293 H 5ug
CD28 Protein activates T-cells promoting cell proliferation cytokine production and T-cell survival It collaborates with TCR/CD3 ligation and CD40L costimulation to boost IL4 and IL10 production in T-cells CD28 Protein forms a disulfide-linked homodimer and interacts with DUSP14 It also binds to CD80/B7-1 and CD86/B7-2/B70 and interacts with GRB2 (By similarity) CD28 Protein Rat (HEK293 His) is the recombinant rat-derived CD28 protein expressed by HEK293 with C-His labeled tag