Rabbit Secondary Antibodies
ABclonal Technology 488 Rabbit anti-Human CD177
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration Mutations in this gene are associated with myeloproliferative diseases Over-expression of this gene has been found in patients with polycythemia rubra vera Autoantibodies against the protein may result in pulmonary transfusion reactions and it may be involved in Wegener s granulomatosis A related pseudogene which is adjacent to this gene on chromosome 19 has been identified
ABclonal Technology 700 Rabbit anti-Human CD89
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils monocytes macrophages and eosinophils where it mediates immunologic responses to pathogens It interacts with IgA-opsonized targets and triggers several immunologic defense processes including phagocytosis antibody-dependent cell-mediated cytotoxicity and stimulation of the release of inflammatory mediators Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene
ABclonal Technology 488 Rabbit anti-Human GATA3
This gene encodes a protein which belongs to the GATA family of transcription factors The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia
ABclonal Technology ABflo 488 Rabbit anti-Rat CD31
Enables protein phosphatase binding activity Involved in several processes including cellular response to interferon-gamma negative regulation of GTPase activity and negative regulation of actin filament polymerization Located in cell surface and ruffle Used to study pulmonary hypertension Biomarker of bacterial pneumonia orchitis and osteoarthritis Human ortholog(s) of this gene implicated in coronary artery disease (multiple) lung non-small cell carcinoma neuroblastoma and psoriatic arthritis Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1)
ABclonal Technology 594 Rabbit anti-Human FATP1
Enables biotin transmembrane transporter activity efflux transmembrane transporter activity and long-chain fatty acid transporter activity Involved in several processes including carboxylic acid transmembrane transport glycerophospholipid biosynthetic process and lipid transport across blood-brain barrier Located in membrane Part of plasma membrane
ABclonal Technology 488 Rabbit anti-Human SIGLEC9
Predicted to enable monosaccharide binding activity and sialic acid binding activity Predicted to be involved in cell adhesion Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis engulfment Predicted to be located in external side of plasma membrane Predicted to be active in plasma membrane
Biotium Secondary Antibody Rat IgG Rabbit CF583R 1/EA
This product is prepared by labeling highly cross-adsorbed rabbit anti-rat IgG (H plus L) with CF and reg 583R dye CF and reg dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness photostability and conjugate specificity compared to other fluorescent dyes
ABclonal Technology PE Rabbit anti-Human Ki67 mAb
Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis
EPICYPHER INC CUTANA RABBIT IGG CUT&RUN
CUTANA™ Rabbit IgG CUT&RUN Negative Control Antibody.100ul.Type: Isotype Control. Format: Affinity Purified IgG
ABclonal Technology RING1B/RNF2 Rabbit mAb
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation The protein encoded by this gene is one of the PcG proteins It has been shown to interact with and suppress the activity of transcription factor CP2 (TFCP2 CP2) Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis as well as in cell proliferation in early development This protein was also found to interact with huntingtin interacting protein 2 (HIP2) an ubiquitin-conjugating enzyme and possess ubiquitin ligase activity
ABclonal Technology 594 Rabbit anti-Human CD30
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is expressed by activated but not by resting T and B cells TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB This receptor is a positive regulator of apoptosis and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
ABclonal Technology APC Rabbit anti-Human CD86 mAb
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily This protein is expressed by antigen-presenting cells and it is the ligand for two proteins at the cell surface of T cells CD28 antigen and cytotoxic T-lymphocyte-associated protein 4 Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response Alternative splicing results in several transcript variants encoding different isoforms
ABclonal Technology APC Rabbit anti-Human CD86 mAb
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily This protein is expressed by antigen-presenting cells and it is the ligand for two proteins at the cell surface of T cells CD28 antigen and cytotoxic T-lymphocyte-associated protein 4 Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response Alternative splicing results in several transcript variants encoding different isoforms
ABclonal Technology PE Rabbit anti-Mouse S100A9
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity Involved in peptidyl-cysteine S-nitrosylation positive regulation of blood coagulation and regulation of translation Acts upstream of or within several processes including actin cytoskeleton reorganization astrocyte development and regulation of integrin biosynthetic process Predicted to be located in cell junction cytosol and nucleoplasm Predicted to be active in cytoplasm extracellular space and nucleus Is expressed in several structures including jaw liver otic capsule skeleton and spleen red pulp Human ortholog(s) of this gene implicated in myocarditis Orthologous to human S100A9 (S100 calcium binding protein A9)
ABclonal Technology KO Validated Ki67 Rabbit
Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis