Rabbit Secondary Antibodies
ABclonal Technology Biotin Rabbit anti-Mouse CD8a
Enables identical protein binding activity Acts upstream of or within several processes including cytotoxic T cell differentiation defense response to virus and positive regulation of calcium-mediated signaling Located in external side of plasma membrane Is expressed in several structures including endocrine gland exocrine gland genitourinary system gut and hemolymphoid system gland Orthologous to human CD8A (CD8a molecule)
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Rabbit Anti-Goat IgG F(ab')2 Fragment Specific
Rhodamine Red-X-AffiniPure Rabbit Anti-Goat IgG F(ab')2 Fragment Specific
ABclonal Technology 594 Rabbit anti-Human CD84
This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells Alternate splicing results in multiple transcript variants
ABclonal Technology 700 Rabbit anti-Human CD55
This gene encodes a glycoprotein involved in the regulation of the complement cascade Binding of the encoded protein to complement proteins accelerates their decay thereby disrupting the cascade and preventing damage to host cells Antigens present on this protein constitute the Cromer blood group system (CROM) Alternative splicing results in multiple transcript variants The predominant transcript variant encodes a membrane-bound protein but alternatively spliced transcripts may produce soluble proteins
ABclonal Technology FITC Rabbit anti-Human CD2 mAb
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition A locus control region (LCR) has been found in the 3 flanking sequence of this gene
ABclonal Technology FITC Rabbit anti-Human CD2 mAb
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition A locus control region (LCR) has been found in the 3 flanking sequence of this gene
ABclonal Technology RING1B/RNF2 Rabbit mAb
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation The protein encoded by this gene is one of the PcG proteins It has been shown to interact with and suppress the activity of transcription factor CP2 (TFCP2 CP2) Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis as well as in cell proliferation in early development This protein was also found to interact with huntingtin interacting protein 2 (HIP2) an ubiquitin-conjugating enzyme and possess ubiquitin ligase activity
ABclonal Technology 594 Rabbit anti-Human CD30
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is expressed by activated but not by resting T and B cells TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB This receptor is a positive regulator of apoptosis and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
ABclonal Technology PE Rabbit anti-Human CD1c mAb
This gene encodes a member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail Alternatively spliced transcript variants of this gene have been observed but their full-length nature is not known
ABclonal Technology PE Rabbit anti-Rat IgG2b Fc
Enables antigen binding activity Acts upstream of or within phagocytosis positive regulation of immune response and positive regulation of phagocytosis Located in extracellular space Part of immunoglobulin complex circulating Orthologous to several human genes including IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker)) IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)) and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker))
ABclonal Technology 488 Rabbit anti-Human PTH1R
The protein encoded by this gene is a member of the G-protein coupled receptor family 2 This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH) The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system Defects in this receptor are known to be the cause of Jansen s metaphyseal chondrodysplasia (JMC) chondrodysplasia Blomstrand type (BOCD) as well as enchodromatosis Two transcript variants encoding the same protein have been found for this gene
ABclonal Technology KO Validated Ki67 Rabbit
Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis
ABclonal Technology KO Validated Ki67 Rabbit
Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis
ABclonal Technology 647 Rabbit anti-Human TREM1
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines as well as increased surface expression of cell activation markers Alternatively spliced transcript variants encoding different isoforms have been noted for this gene