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Filtered Search Results
Immunoreagents Inc RABBIT A-GOAT IGG (H&L) AP 1MG
Secondary Antibody; Rabbit anti-goat IgG (H&L), F(ab)'2 fragment, Affinity Pure, Host: Rabbit, Format: Liq, Label: None, Applications: WB, ELISA, IHC/ICC, IF, IP, FC
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Cayman Chemical RabbIt ntIGoat IgG EuW1024 1mg
Concentration: 1 mg/ml Antibody: Rabbit poyclonal anti-Goat IgG Excitation max. λ: 340 nm Emission max. λ: 615 nm Uses: TR-FRET and High throughput screening (HTS) applications Form: Conjugate supplied as a liquid in 50 mn Tris (pH 7.8) + 0.9% NaCl + 0.05% NaN3
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Cayman Chemical ZAP70NTerm RabbIt Moncl 100uL
A synthetic intermediate has been used in the synthesis of ANANAS and chemotherapeutic conjugates
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Cayman Chemical BOB1OBF1CTerm RabbIt M 100uL
A GRK inhibitor (IC50s 3.9 0.15 and 0.38 M for GRK1 GRK2 and GRK5 respectively) selective for GRKs over PKA (IC50 120 M) increases contractility in isoproterenol-stimulated isolated mouse cardiomyocytes at 500 nM prevents the desensitization of histamine H1 receptor- and purinergic P2Y2 receptor-driven phospholipase C signaling in human ULTR myometrial cells and isolated rat MSMCs respectively (IC50s 3.09 and 2.95 M respectively)
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ABclonal Technology 488 Rabbit anti-Human MRC2
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This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer gliomas and metastatic bone disease
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ABclonal Technology 647 Rabbit anti-Human MRC2
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This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer gliomas and metastatic bone disease
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ABclonal Technology PE Rabbit anti-Human CD4 mAb
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This gene encodes the CD4 membrane glycoprotein of T lymphocytes The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit This gene is expressed not only in T lymphocytes but also in B cells macrophages granulocytes as well as in various regions of the brain The protein functions to initiate or augment the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene
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ABclonal Technology 450 Rabbit anti-Human CD89
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This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils monocytes macrophages and eosinophils where it mediates immunologic responses to pathogens It interacts with IgA-opsonized targets and triggers several immunologic defense processes including phagocytosis antibody-dependent cell-mediated cytotoxicity and stimulation of the release of inflammatory mediators Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene
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ABclonal Technology ABflo 594 Rabbit anti- IgG1
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Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
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ABclonal Technology 647 Rabbit anti-Human CD98
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This gene is a member of the solute carrier family and encodes a cell surface transmembrane protein The protein exists as the heavy chain of a heterodimer covalently bound through di-sulfide bonds to one of several possible light chains The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids Alternatively spliced transcript variants encoding different isoforms have been characterized
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ABclonal Technology 647 Rabbit anti-Human CD98
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This gene is a member of the solute carrier family and encodes a cell surface transmembrane protein The protein exists as the heavy chain of a heterodimer covalently bound through di-sulfide bonds to one of several possible light chains The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids Alternatively spliced transcript variants encoding different isoforms have been characterized
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ABclonal Technology PE Rabbit anti-Mouse CD44 mAb
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This gene enables hyaluronic acid and type II TGF-beta receptor binding contributing to cytokine binding and receptor activity It regulates T cell activation protein phosphorylation and intracellular signaling Involved in Wnt signaling epithelium morphogenesis and wound healing it plays a role in inflammatory response Located in the basolateral plasma membrane external plasma membrane and microvilli it is part of the macrophage migration inhibitory factor receptor complex Expressed in various systems including alimentary branchial arch CNS genitourinary and limb Human orthologs are linked to breast carcinoma multiple carcinomas and prostate cancer It is orthologous to human CD44 a molecule in the Indian blood group
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ABclonal Technology 488 Rabbit anti-Human KLRG1
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation They can also regulate specific humoral and cell-mediated immunity The protein encoded by this gene belongs to t
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ABclonal Technology 647 Rabbit anti-Human CD34
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The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C Two transcript variants encoding different isoforms have been found for this gene
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ABclonal Technology 488 Rabbit anti-Human CD314
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Natural killer (NK) cells are lymphocytes capable of lysing tumor and virus-infected cells without prior activation as well as regulating immunity NK cells express several calcium-dependent (C-type) lectins which influence their function The NKG2 gene family located in the NK complex includes genes expressed in NK cells This gene encodes a transmembrane protein with a C-type lectin domain binding ligands like MHC class I chain-related A and B proteins and UL-16 binding proteins Ligand-receptor interactions activate NK and T cells aiding immune system recognition of stressed cells This protein and its ligands are potential therapeutic targets for immune diseases and cancers Read-through transcription occurs between this gene and the upstream KLRC4 family member in the same cluster
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