Rabbit Secondary Antibodies
Carbosynth LLC. Rabbit anti Hu IgM (mu chain), 1 mg
Rabbit anti Human IgM (mu chain) secondary antibody
ABclonal Technology 488 Rabbit anti-Human Nectin-4
Nectin-4 poliovirus Receptor-like 4 (PVRL4) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily that promotes intercellular adhesion by acting as a major component of adhesion junctions The extracellular domain of Nectin-4 consists of one Ig variable region (V) and two Ig constant regions (C) which mediate binding to measles virus and adjacent cells through trans-heterophile interactions with Nectin-1 Unlike other members of the connectin family which are widely expressed in adult tissues human Nectin-4 expression is largely limited to the blastoderm Studies have shown that Nectin-4 is overexpressed in cells from a variety of human solid tumors including pancreatic breast lung and ovarian cancers The expression pattern of Nectin-4 in normal tissues is limited so NECTIN-4 can be used as a novel therapeutic target for various human tumors
ABclonal Technology 488 Rabbit anti-Human IL8
The protein encoded by this gene interleukin-8 (IL-8) is a CXC chemokine and major mediator of the inflammatory response IL-8 is secreted by various cells including macrophages neutrophils and T lymphocytes and acts as a chemotactic factor guiding neutrophils to infection sites It is rapidly induced by bacterial and viral products and plays a role in systemic inflammatory response syndrome (SIRS) IL-8 contributes to bronchiolitis caused by respiratory syncytial virus (RSV) and is involved in lung inflammation in cystic fibrosis It is also linked to coronary artery disease endothelial dysfunction and promotes tumor migration angiogenesis and metastasis IL-8 binds to the CXCR2 receptor increasing blood vessel permeability Elevated IL-8 levels correlate with disease severity including sepsis This gene is part of a CXC chemokine gene cluster on chromosome 4q
ABclonal Technology APC Rabbit anti-Human IL-2 mAb
This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4 IL7 IL9 IL15 IL21 erythropoietin and thrombopoietin The protein encoded by this gene is a secreted cytokine produced by activated CD4 and CD8 T lymphocytes that is important for the proliferation of T and B lymphocytes The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7 The expression of this gene in mature thymocytes is monoallelic which represents an unusual regulatory mode for controlling the precise expression of a single gene The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease which suggests an essential role of this gene in the immune response to antigenic stimuli
ABclonal Technology PE Rabbit anti-Human CD72 mAb
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
ABclonal Technology 647 Rabbit anti-Human CD58
This gene encodes a member of the immunoglobulin superfamily The encoded protein is a ligand of the T lymphocyte CD2 protein and functions in adhesion and activation of T lymphocytes The protein is localized to the plasma membrane Alternatively spliced transcript variants have been described
ABclonal Technology PE Rabbit anti-Human CD44V6
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions cell adhesion and migration It is a receptor for hyaluronic acid (HA) and can also interact with other ligands such as osteopontin collagens and matrix metalloproteinases (MMPs) This protein participates in a wide variety of cellular functions including lymphocyte activation recirculation and homing hematopoiesis and tumor metastasis Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms however the full length nature of some of these variants has not been determined Alternative splicing is the basis for the structural and functional diversity of this protein and may be related to tumor metastasis
Medchemexpress LLC FITC-conjugated Rabbit Anti-Human IgG H&L | 50 UL
FITC-conjugated Rabbit Anti-Human IgG H&L is a fluorescein isothiocyanate (FITC) labeled and rabbit-derived polyclonal antibody, which served as the secondary antibody.
- Host: Rabbit
- Immunogen: Native Human IgG
- Conjugation: FITC
- Modification: Unmodified
- Isotype: IgG
- Appearance: Liquid
- Applications: ICC/IF, FC
- Clonality: Polyclonal
- Species reactivity: Human
- Purity: Affinity purified
- Storage & stability: Stored at -20°C for 1 year. Protect from light. Avoid repeated freeze / thaw cycles.
ABclonal Technology 647 Rabbit anti-Human TROP-2
This intronless gene encodes a carcinoma-associated antigen This antigen is a cell surface receptor that transduces calcium signals Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy
ABclonal Technology PE Rabbit anti-Human CaSR mAb
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling and thus this protein plays an essential role in maintaining mineral ion homeostasis Mutations in this gene are a cause of familial hypocalciuric hypercalcemia neonatal severe hyperparathyroidism and autosomal dominant hypocalcemia
ABclonal Technology 594 Rabbit anti-Human CD6
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule The gene product is important for continuation of T cell activation This gene may be associated with susceptibility to multiple sclerosis (PMID 19525953 21849685) Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 594 Rabbit anti-Human LAMP2
The protein encoded by this gene is a member of a family of membrane glycoproteins This glycoprotein provides selectins with carbohydrate ligands It may play a role in tumor cell metastasis It may also function in the protection maintenance and adhesion of the lysosome Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins
ABclonal Technology 488 Rabbit anti-Human CD314
Natural killer (NK) cells are lymphocytes capable of lysing tumor and virus-infected cells without prior activation as well as regulating immunity NK cells express several calcium-dependent (C-type) lectins which influence their function The NKG2 gene family located in the NK complex includes genes expressed in NK cells This gene encodes a transmembrane protein with a C-type lectin domain binding ligands like MHC class I chain-related A and B proteins and UL-16 binding proteins Ligand-receptor interactions activate NK and T cells aiding immune system recognition of stressed cells This protein and its ligands are potential therapeutic targets for immune diseases and cancers Read-through transcription occurs between this gene and the upstream KLRC4 family member in the same cluster
ABclonal Technology PE Rabbit anti-Human/ FOXP3
The protein encoded by this gene is a member of the forkhead winged-helix family of transcriptional regulators Defects in this gene are the cause of immunodeficiency polyendocrinopathy enteropathy X-linked syndrome (IPEX) also known as X-linked autoimmunity-immunodeficiency syndrome Alternatively spliced transcript variants encoding different isoforms have been identified