Rabbit Secondary Antibodies
ABclonal Technology 594 Rabbit anti-Human CD300a
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Human CR2/CD21
This gene encodes a membrane protein which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Human CD80/B7-1
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4 The activated protein induces T-cell proliferation and cytokine production This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy
ABclonal Technology 647 Rabbit anti-Human CD94
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation Several genes of the C-type lectin superfamily including members of the NKG2 family are expressed by NK cells and may be involved in the regulation of NK cell function KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus Three transcript variants encoding two different isoforms have been found for this gene
ABclonal Technology 488 Rabbit anti-Human IL-1B
The protein encoded by this gene is a member of the interleukin 1 cytokine family This cytokine is produced by activated macrophages as a proprotein which is proteolytically processed to its active form by caspase 1 (CASP1 ICE) This cytokine is an important mediator of the inflammatory response and is involved in a variety of cellular activities including cell proliferation differentiation and apoptosis The induction of cyclooxygenase-2 (PTGS2 COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2
ABclonal Technology PE Rabbit anti-Human CD1B mAb
This gene encodes a member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification to bind lipid antigens
ABclonal Technology 647 Rabbit anti-Human CD300a
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 700 Rabbit anti-Human CD89
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils monocytes macrophages and eosinophils where it mediates immunologic responses to pathogens It interacts with IgA-opsonized targets and triggers several immunologic defense processes including phagocytosis antibody-dependent cell-mediated cytotoxicity and stimulation of the release of inflammatory mediators Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene
ABclonal Technology 594 Rabbit anti-Human IL23R
The protein encoded by this gene is a subunit of the receptor for IL23A IL23 This protein pairs with the receptor molecule IL12RB1 IL12Rbeta1 and both are required for IL23A signaling This protein associates constitutively with Janus kinase 2 (JAK2) and also binds to transcription activator STAT3 in a ligand-dependent manner
ABclonal Technology 594 Rabbit anti-Human CD2
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition A locus control region (LCR) has been found in the 3 -apos flanking sequence of this gene [provided by RefSeq Jun 2016]
Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure Rabbit Anti-Human IgM Fc5µ Fragment Specific (min X Ms Sr Prot)
Alexa Fluor 488-AffiniPure Rabbit Anti-Human IgM Fc5µ Fragment Specific (min X Ms Sr Prot)
ABclonal Technology 647 Rabbit anti-Human TREM1
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines as well as increased surface expression of cell activation markers Alternatively spliced transcript variants encoding different isoforms have been noted for this gene
ABclonal Technology 594 Rabbit anti-Human CD47
This gene encodes a membrane protein which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin and it may play a role in membrane transport and signal transduction This gene has broad tissue distribution and is reduced in expression on Rh erythrocytes Alternatively spliced transcript variants have been found for this gene
ABclonal Technology 488 Rabbit anti-Human TROP-2
This intronless gene encodes a carcinoma-associated antigen This antigen is a cell surface receptor that transduces calcium signals Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy