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Filtered Search Results
ABclonal Technology Pepsinogen II PG II Rabbit mAb
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This gene encodes an aspartic proteinase that belongs to the peptidase family A1 The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa This protein is also secreted into the serum This protein is synthesized as an inactive zymogen that includes a highly basic prosegment This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself Polymorphisms in this gene are associated with susceptibility to gastric cancers Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis Alternate splicing results in multiple transcript variants A pseudogene of this gene is found on chromosome 1
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Immunology Consultants anti-Mouse IgG h+l Antibody (Rabbit) - Affinity Purified
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RGHL‑90A is an affinity‑purified rabbit antibody specific for mouse IgG heavy and light chains, designed for use as a secondary antibody in immunoassays. This reagent provides strong, selective binding and low background, supporting reliable detection in ELISA, Western blotting, and other immunochemical applications. Produced by Immunology Consultants and supplied in a 1 mg format, RGHL‑90A is an essential tool for researchers working with murine antibodies.
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Cayman Chemical Cell-Based Alkaline Phosphata
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An analytical reference standard categorized as a precursor in the synthesis of cathinones intended for research and forensic applications
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CPC Scientific (Tos-Gly-Pro-Arg)2-R110 (trifluoroacetate salt) 0.5MG
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Thrombin.ONE-LETTER SEQUENCE: (Tos-GPR)2-R110MOLECULAR FORMULA: C60H70N14O13S2MOLECULAR WEIGHT:1259.5STORAGE CONDITIONS: -20 5CRESEARCH AREA: HematologyREFERENCES: Biol Chem Hoppe-Seyler 373, 433 (1992); Nature 361, 274 (1993)
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Jackson Immuno Research Labs Biotin-SP-AffiniPure Rabbit Anti-Horse IgG (H+L)
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Biotin-SP-AffiniPure Rabbit Anti-Horse IgG (H+L)
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Cayman Chemical PrecoatedMouse ntI-RabbIt 1ea
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An ago-PAM of a7 nAChRs enhances ACh-induced activation in a two-electrode voltage-clamp assay using Xenopus oocytes expressing the human a7 nAChR at 10 UM decreases paw edema and induces antinociception in the first and second phase of the formalin test in a mouse model of inflammatory pain at 10 mg/kg inhibits tau aggregation induced by seeding with insoluble human tau isolated from a patient with Alzheimers disease in primary rat neurons
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Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure Rabbit Anti-Chicken IgY (IgG) F(ab')2 Fragment Specific
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Alexa Fluor 488-AffiniPure Rabbit Anti-Chicken IgY (IgG) F(ab')2 Fragment Specific
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ABclonal Technology PE Rabbit anti-Human MRC2 mAb
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This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer gliomas and metastatic bone disease
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Jackson Immuno Research Labs AMCA-AffiniPure Rabbit Anti-Human IgG (H+L)
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AMCA-AffiniPure Rabbit Anti-Human IgG (H+L)
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ABclonal Technology PE Rabbit anti-Human CaSR mAb
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The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling and thus this protein plays an essential role in maintaining mineral ion homeostasis Mutations in this gene are a cause of familial hypocalciuric hypercalcemia neonatal severe hyperparathyroidism and autosomal dominant hypocalcemia
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ABclonal Technology 594 Rabbit anti-Human TREM1
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This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines as well as increased surface expression of cell activation markers Alternatively spliced transcript variants encoding different isoforms have been noted for this gene
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ABclonal Technology PE Rabbit anti-Human MERTK mAb
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This gene is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains two Ig-like C2-type (immunoglobulin-like) domains and one tyrosine kinase domain Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP)
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Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure Rabbit Anti-Human IgM Fc5µ Fragment Specific (min X Ms Sr Prot)
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Alexa Fluor 594-AffiniPure Rabbit Anti-Human IgM Fc5µ Fragment Specific (min X Ms Sr Prot)
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ABclonal Technology 647 Rabbit anti-Human Ki67
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Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis
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ABclonal Technology 488 Rabbit anti-Human CD204
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This gene encodes class A macrophage scavenger receptors which produce three isoforms (1 2 and 3) via alternative splicing These trimeric integral membrane glycoproteins are macrophage-specific and involved in various processes like atherosclerosis Alzheimer s disease and host defense Isoforms 1 and 2 mediate the endocytosis of modified low-density lipoproteins (LDLs) while isoform 3 despite having the necessary domain cannot internalize modified LDL due to altered intracellular processing and trapping within the endoplasmic reticulum Isoform 3 also inhibits the function of isoforms 1 and 2 when co-expressed suggesting a regulatory mechanism for scavenger receptor activity in macrophages
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