Rabbit Secondary Antibodies
ABclonal Technology BLBP/FABP7 Rabbit mAb
The gene encodes a small highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands The encoded protein is important in the establishment of the radial glial fiber in the developing brain Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms Pseudogenes of this gene are found on multiple chromosomes
Meridian Life Science RABBIT A'AMYLOID PRECURSOR PRO
Amyloid Precursor Protein (C-Terminal) (a.a. 737-751)
ABclonal Technology BOK Rabbit mAb
The protein encoded by this gene belongs to the BCL2 family members of which form homo- or heterodimers and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes Studies in rat show that this protein has restricted expression in reproductive tissues interacts strongly with some antiapoptotic BCL2 proteins not at all with proapoptotic BCL2 proteins and induces apoptosis in transfected cells Thus this protein represents a proapoptotic member of the BCL2 family
ABclonal Technology GNAQ Rabbit mAb
This locus encodes a guanine nucleotide-binding protein The encoded protein an alpha subunit in the Gq class couples a seven-transmembrane domain receptor to activation of phospolipase C-beta Mutations at this locus have been associated with problems in platelet activation and aggregation A related pseudogene exists on chromosome 2
Cayman Chemical CD20CTerm RabbIt Monclon 100uL
A selective estrogen receptor covalent antagonist covalently modifies cysteine 530 in the ligand binding domain of wild-type ERa and ERaY537S inhibits expression of the ERa target genes GREB1 and TFF1 in MCF-7 cells overexpressing wild-type ERa (IC50s 2.74 and 1.3 nM respectively) ERaY537S (IC50s 29.38 and 19.4 nM respectively) ERaY537N (IC50s 8.14 and 6.1 nM respectively) ERaY537C (IC50s 12.19 and 9.5 nM respectively) or ERaD538G (IC50s 24.87 and 4 nM respectively) inhibits the growth of MCF-7 cells overexpressing wild-type ERa or ERaY537S (GI50s 1.3 and 8.3 nM respectively) reduces tumor growth in an MCF-7 mouse xenograft model and an ERaY537S/WT ST941 PDX mouse model in a dose-dependent manner
Cayman Chemical cKItCD117CTerm RabbIt M 100uL
An internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium by GC- or LC-MS
ABclonal Technology MTAP Rabbit mAb
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine The encoded enzyme is deficient in many cancers Multiple alternatively spliced transcript variants have been described for this gene
Meridian Life Science RABBIT A' C.BOTULINUM TYPE A
Clostridium botulinum Type A Neurotoxin Light Chain
ABclonal Technology GPR109A/HM74A/HCAR2 Rabbit mAb
Predicted to enable nicotinic acid receptor activity Involved in neutrophil apoptotic process and positive regulation of neutrophil apoptotic process Located in cell junction and plasma membrane
ABclonal Technology PRD Rabbit mAb
This gene encodes a member of the peptidase family The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues The enzyme serves an important role in the recycling of proline and may be rate limiting for the production of collagen Mutations in this gene result in prolidase deficiency which is characterized by the excretion of large amount of di- and tri-peptides containing proline Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology ATG12 Rabbit mAb
Autophagy is a process of bulk protein degradation in which cytoplasmic components including organelles are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al 1998 [PubMed 9852036])
ABclonal Technology PE Mouse anti-Rabbit IgG Fc
Secondary antibodies are affinity-purified antibodies which will work with target-specific primary antibody in the detection sorting or purification of its specified target Secondary antibodies offer increased versatility enabling users to use many detection systems (e g HRP AP fluorescence) They can also provide greater sensitivity through signal amplification as multiple secondary antibodies Most commonly secondary antibodies are generated by immunizing the host animal (different from host species of primary antibody) with a pooled population of normal immunoglobulins from the host species of primary antibody and can be further purified and modified (i e antibody fragmentation label conjugation etc ) to ensure well-characterized specificity to corresponding normal immunoglobulins