Cell Based Assays
Eurofins Discoverx ADP Hunter Plus, 24 (2,400dp, 384-well). (90-0083M)
The ADP Hunter Plus kit is a detection kit for the measurement of ADP produced as a product of kinase activity. It is used to detect substrate-induced activity of purified or semi-purified kinases. ADP produced by the kinase reacts with intermediate factors to produce a fluorescent dye precursor, which generates signal when combined with peroxide and peroxidase. The kit uses an end-point read. This detection kit contains reagents for 6 plates (384-well). For detailed product information, visit www.discoverx.com/products-applications/biochemical-assays.
Eurofins Discoverx PathHunter eXpress PROKR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0282E2CP2L)
The PathHunter PROKR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokinectin, EG-VEGF) based activation of PROKR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PROKR2 and EA-tagged β-Arrestin-2. Activation of PROKR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress HRH2 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0043E2CP2L)
The cAMP Hunter HRH2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HRH2, a naturally Gs coupled GPCR. Upon activation of HRH2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Bioss Glutathione Reductase Monoclon
Glutathione Reductase Primary Antibody Unconjugated Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
Eurofins Discoverx cAMP Hunter eXpress rDRD2L (Long Isoform) CHO-K1 GPCR Assay, 2pl Kit. (95-0130E2CP2M)
The cAMP Hunter rDRD2L eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine, pergolide) based activation of rDRD2L GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type rDRD2L, a naturally Gi/Go coupled GPCR. Upon activation of rDRD2L, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCX3CR1 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0702E2MCP2L)
The PathHunter mCX3CR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CX3CL1, fractalkine) based activation of mCX3CR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCX3CR1 and EA-tagged β-Arrestin-2. Activation of mCX3CR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress OPRK1 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0234E3CP5L)
The PathHunter OPRK1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dynorphin A) based activation of OPRK1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRK1 and EA-tagged β-Arrestin-2. Activation of OPRK1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress FPRL1 Activated GPCR Internalization Assay, 2pl Kit. (93-0666E3CP0M)
The PathHunter FPRL1 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of FPRL1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged FPRL1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting FPRL1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx KILR Detection Kit, 1,000 dp (96-well). (97-0001M)
The KILR Detection Kit is a detection kit intended for use with KILR cell lines or pools when running ADCC or other lysis-based assays. This kit contains exogenous EA as well as EFC substrate to allow for detection of lysis-based release of ProLabel-tagged KILR reporter protein. This kit contains all components required to assay 10 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-97-0001m.
Eurofins Discoverx PathHunter eXpress GPR123 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0417E2ACP1L)
The PathHunter GPR123 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR123 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR123 and EA-tagged β-Arrestin-2. Activation of GPR123 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress NTSR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0280E2CP0L)
The PathHunter NTSR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neurotensin) based activation of NTSR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged NTSR1 and EA-tagged β-Arrestin-2. Activation of NTSR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Total Histone H3 Detection Kit, Control Lysate
HTRF Total Histone H3 Detection Kit, Control Lysate
Eurofins Discoverx cAMP Hunter eXpress CCR5 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0068E2CP2L)
The cAMP Hunter CCR5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL3) based activation of CCR5 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CCR5, a naturally Gi/Go coupled GPCR. Upon activation of CCR5, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cusabio Technology LLC kallikrein-related peptidase 5
This ELISA kit is designed for the quantitative detection of Human Kallikrein-5 (KLK5) in diverse biological samples including serum plasma cell culture supernatants tissue homogenates and saliva Utilizing a sandwich assay format the kit offers a broad detection range of 62 5 pg/mL to 4000 pg/mL with a sensitivity of 15 6 pg/mL ensuring precise measurement of KLK5 concentrations The assay requires only 50-100 L of sample per test and delivers results within 1-5 hours Detection is performed at 450 nm providing reliable and reproducible data for research applications This kit is optimized for accuracy and efficiency making it suitable for studies requiring sensitive quantification of KLK5 in multiple sample matrices
Eurofins Discoverx cAMP Hunter eXpress FFAR3 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0136E2CP2M)
The cAMP Hunter FFAR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. FFAs) based activation of FFAR3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type FFAR3, a naturally Gi/Go coupled GPCR. Upon activation of FFAR3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.