Apoptosis Reagents and Kits
Apexbio Technology LLC Annexin V-Cy5/DAPI Apoptosis Kit 20assays
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS is localized on the inner leaflet of the cell membrane lipid bilayer During the early stages of apoptosis PS translocates from the inner leaflet to the outer surface of the cell membrane exposing it to the extracellular environment Due to Annexin V s high affinity for PS fluorescently labeled Annexin V (Cy5) can be used as a fluorescent probe to detect apoptotic cells through flow cytometry or fluorescence microscopy with staining taking only 10-20 minutes DAPI specifically binds to double-stranded DNA emitting blue fluorescence but normally cannot permeate intact cell membranes However DAPI can enter late-stage apoptotic or dead cells and stain their nuclei Simultaneous staining with Annexin V-Cy5 and DAPI allows differentiation of cells at various stages of apoptosis and cell death
Apexbio Technology LLC Annexin V-PE/7-AAD Apoptosis Kit 200tests
Annexin V-PE/7-AAD Apoptosis Kit enables differentiation between early apoptotic late apoptotic and dead cells Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) PS is normally located on the inner leaflet of the cell membrane phospholipid bilayer However during the early stages of apoptosis PS moves from the inner surface to the outer surface of the cell membrane becoming exposed to the extracellular environment Labeled with a fluorescence dye such as PE Annexcin V is commonly used as a fluorescent probe to detect apoptosis through flow cytometry or fluorescence microscopy within 15-30 minutes In addition this kit includes 7-AAD a nucleic acid dye that specifically binds double-stranded DNA and emits red fluorescence Normally 7-AAD cannot permeate intact cell membranes however it can penetrate compromised membranes of late apoptotic and dead cells staining their nuclei
Selleck Chemical LLC Mitochondrial Fusion Promoter M1 S3375-5mg
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator that increases the expression of mitofusin 2 a mitochondrial outer membrane fusion protein reduces brain mitochondrial dysfunction Mitochondrial fusion promoter M1 alleviates brain damage in rats with cardiac ischemia/reperfusion injury
IMMUNOCHEMISTRY TECHNOLOGY LLC FAM-FLICA CASPASE-8 ASSAY KIT
NC1481391 FAM-FLICA CASPASE-8 ASSAY KIT
Apexbio Technology LLC Annexin V-FITC Apoptosis Kit, 100Assays Cas No: NA MFCD: NA
Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin. Annexin V has a high affinity to PS and is used as a probe to detect cells that have expressed PS on the cell surface. After initiating apoptosis, cells translocate phosphatidylserine (PS) from the inner face of the plasma membrane to the cell surface soon, which can be easily detected by Annexin V. There are other sizes available. Please inqury us for quote.
Abcam JC-1 - Mitochondrial Membrane Potential Assay Kit
JC-1 - Mitochondrial Membrane Potential Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Biotium Dual Apoptosis Assay with NucView 488 Caspase-3 Substrate and CF640R-Annexin V (50 assays)
Dual Apoptosis Assay with NucView 488 Caspase-3 Substrate and CF640R-Annexin V (50 assays)
Biolegend APC Annexin V Reactivity, 300 tests
APC Annexin V Reactivity: All mammalian species; Apps: FC; Size: 300 tests
Abcam Caspase-3, Caspase-8 and Caspase-9 Multiplex Activity Assay Kit (Fluorometric)
Caspase-3, Caspase-8 and Caspase-9 Multiplex Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Biotium ANNEXIN V CF DYE CF405M 5UG
Annexin V CF® Dye Conjugates, Azide-Free, Lyophilized - 5 ug, CF®405M
Enzo Life Sciences GFP-CERTIFIED Apoptosis/Necrosis detection kit (1x100assays)
Multiplex assay that distinguishes between healthy, early apoptotic, late apoptotic and necrotic cells, compatible with GFP and other green fluorescent probes. Applications: Flow Cytometry. Fluorescence microscopy. Fluorescent detection. Contents: Apoptosis Detection Reagent (Annexin V-EnzoGold). Necrosis Detection Reagent. Apoptosis Inducer (Staurosporine). Binding Buffer (10X)
Sigma Aldrich Fine Chemicals Biosciences Duolink(R) In Situ Detection Reagents Orange | 30RXN
Duolink(R) In Situ Detection Reagents Orange | 30RXN
Biotium JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays)
The loss of mitochondrial membrane potential is a hallmark for apoptosis. It is an early event preceding phosphatidylserine externalization and coinciding with caspase activation. JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells. In non-apoptotic cells, JC-1 accumulates as aggregates in the mitochondrial membranes, resulting in red fluorescence (590 nm). The brightness of red fluorescence is proportional to the potential and varies among different cell types. However, in apoptotic and necrotic cells, which have diminished mitochondrial membrane potential, JC-1 exists in the green fluorescent (529 nm) monomeric form. This kit provides a step-by-step protocol and ready-to-use reagents for performing assays for flow cytometry, fluorescence microscopy, or fluorometric microplate reader.