Apoptosis Reagents and Kits
Biotium Annexin V, CF488A Conjugate, Azide-Free, Lyophilized
CF488A Annexin V is a green fluorescent conjugate (Ex/Em 490/515 nm) that can be used to stain phosphatidylserine on the surface of apoptotic cells. This Annexin V conjugate is supplied lyophilized and azide-free, compatible with real-time imaging of live cells. Unit size 5 ug.
Biotium NucView 488 and RedDot™ 2 Apoptosis & Necrosis Kit (100 assays)
NucView488 and RedDot™ Apoptosis/Necrosis Assay Kit contains NucView488 Caspase-3 Substrate for detection of caspase-3/7 activity. The far-red dead-cell stain RedDot™ is included for staining necrotic and late apoptotic cells that have compromised plasma membrane integrity. This kit provides a convenient tool for profiling apoptotic and necrotic cell populations by fluorescence microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView488 Caspase-3 Substrate can be used to detect caspase-3/7 activity within individual intact cells without inhibiting apoptosis progression. RedDot™ is a cell membrane-impermeable, far-red dye with high selectivity for membrane compromised or dead cells. RedDot™ has far-red emission at 695 nm for detection in the Cy5 channel, well-separated from the green fluorescence of NucView488. The kit has reagents sufficient for 100 assays for flow cytometry.
Biotium Ethidium homodimer III
Ethidium Homodimer III, also known as EthD-III, is a red fluorescent dead cell stain for bacteria and mammalian cells. It is a cell membrane-impermeant nucleic acid dye that only stains dead cells with damaged cell membranes. Ethidium Homodimer III was developed by Biotium as a superior alternative to Ethidium Homodimer I. The absorption and emission spectra are similar, but EthD-III is 45% brighter. Ethidium Homodimer III is useful for detecting dead bacteria or mammalian cells by fluorescence microscopy or flow cytometry. Properties: Red solid souble in DMSO, MeOH, or H2O; Store at 4°C, protect from light; Ex/Em = 279, 522/593 nm (with DNA); MW: ~1000.
Apexbio Technology LLC Annexin V-Biotin Apoptosis Kit, 25 assays
Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin. Annexin V has a high affinity to PS and is used as a probe to detect cells that have expressed PS on the cell surface. After initiating apoptosis, cells translocate phosphatidylserine (PS) from the inner face of the plasma membrane to the cell surface soon, which can be easily detected by Annexin V.Annexin V-Biotin Apoptosis Detection Kit uses Biotin-conjugated Annexin V that can easily detect PS on the cell surface after initiating apoptosis. Annexin V-Biotin can be easily detected in combination with conventional dye-staining using any avidin- or streptavidine-dye reagents, such as (strept)avidine-peroxidase, -fluorescein, -alkaline phosphatase (AP), and --gal, etc. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC Annexin V-Cy3 Apoptosis Kit, 100 assays. Cas: MFCD: NA. Detects Apoptosis within 10 min.
Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin. Annexin V has a high affinity to PS and is used as a probe to detect cells that have expressed PS on the cell surface. After initiating apoptosis, cells translocate phosphatidylserine (PS) from the inner face of the plasma membrane to the cell surface soon, which can be easily detected by Annexin V.Annexin V-Cy3 Apoptosis Detection Kit uses a fluorescent conjugate of Annexin V that can easily detect PS on the cell surface after initiating apoptosis. The one-step staining procedure needs only 10 minutes. The result can be analyzed by fluorescence microscopy or by flow cytometry. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Flavokawain A | 3420-72-2 | 100 MG
Flavokawain A is a chalcone compound and an orally active inhibitor of PRMT5 and cytochrome P450. It exhibits anti-inflammatory, anti-tumor, and immunomodulatory effects. It can inhibit the proliferation of tumor cells and induce apoptosis and is used in research for diseases such as bladder cancer.
- Inhibits proliferation of tumor cells and induces apoptosis
- Exhibits anti-inflammatory, anti-tumor, and immunomodulatory effects
- Used in research for diseases such as bladder cancer
- Inhibitor of PRMT5 and cytochrome P450
Biolegend Pacific Blue™ Annexin V
Pacific Blue™ Annexin V Reactivity: All mammalian species; Apps: FC; Size: 100 tests
Ubpbio Nutlin-3, 5MG
Nutlin-3 is a potent and selective small chemical compound that binds murine double minutes (MDM2) and blocks the MDM2/p53 interaction, by which nutlin-3 functions to stabilize p53 and induces senescence in cancer cells that express wild type p53.
AdipoGen SB202190,Chemical. CAS: 152121-30-7
SB202190, AdipoGen Life Sciences. Chemical. CAS: 152121-30-7. Formula: C20H14FN3O. MW: 331.3. Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Autophagic vacuole inducer
Abcam Human KDM5C (Jarid1C / SMCX) knockout HEK-293T cell lysate.
Human KDM5C (Jarid1C / SMCX) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human DSG2 (Desmoglein 2) knockout HeLa cell lysate.
Human DSG2 (Desmoglein 2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CD47 knockout HEK-293T cell lysate.
Human CD47 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ARRB2 (Beta Arrestin 2) knockout Hep G2 cell lysate.
Human ARRB2 (Beta Arrestin 2) knockout Hep G2 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement