Neuroscience Reagents and Kits
Apexbio Technology LLC Clozapine is an atypical antipsychotic medication 5786-21-0. MFCD00153785
Clozapine is an atypical antipsychotic medication 5786-21-0. MFCD00153785
Enzo Life Sciences Compound E, (250µg), CAS Number: 209986-17-4
γ-Secretase inhibitor. Cell permeable, potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC50=0.3nM for total β-amyloid) and Notch processing, which ceases cell differentiation. At higher concentrations (20-400µM), only weakly affects the presenilase activity. Activity tested!. Alternative Name: (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide, γ-Secretase Inhibitor, GSI. Formula: C27H24F2N4O3. MW: 490.5. CAS Number: 209986-17-4. Purity: ≥95% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: -20°C
Cayman Chemical Testosteron AChE Tracer 500dtn
An agonist of GLP-1R (Ki 1.1 nM for the human receptor) induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R (EC50 0.06 nM) decreases blood levels of glucose and increases blood levels of insulin in an oral glucose tolerance test in Zucker diabetic obese rats at 1 mg/animal per week reduces blood levels of GIP plasma levels of triglycerides and body weight in the same model
Cayman Chemical ResolvIn D1 AChE Tracer 100dtn
A chromogenicBxylosidase substrate upon hydrolysis byBxylosidase 4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure ofBxylosidase activity
Cayman Chemical Latnoprost AChE Tracer 500dtn
A multi-kinase inhibitor inhibits VEGFR2 PDGFRB FLT3 and c-Kit (IC50s 1.12 0.13 0.63 and 0.14 nM respectively) and is selective for these kinases over RET and AMPKa1 (IC50s 74.1 and 352.2 nM respectively) inhibits VEGF-induced proliferation of HUVECs (IC50 31 nM) decreases VEGF-induced capillary tube formation in HUVECs at 1 UM reduces FBS-induced migration of HUVECs at 0.01 or 0.1 UM reduces tumor volume and growth alone and in combination with gefitinib in an HCC827 NSCLC mouse xenograft model at 80 mg/kg per day