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Reaction buffers for use in experiments involving modifying enzymes. Different buffer solutions create optimal reaction conditions for specific modifying enzymes, or facilitate multiple enzymatic reactions.
Casein kinase inhibitor A86 is a potent small-molecule inhibitor of casein kinase 1α (CK1α) with reported activity against CDK7 and CDK9. Supplied as a 10 mM solution in DMSO, it is intended for biochemical and cell-based research applications, including studies of apoptosis and leukemia-related signaling pathways.
Potent CK1α inhibitor with activity against CDK7 and CDK9.
Supplied as a 10 mM solution in DMSO for ready use in assays.
High purity suitable for research: 99.3%.
Molecular formula C18H25FN6; molecular weight 344.43 g/mol.
Volume 1 mL, convenient for small-scale experiments.
For research use only; not for human therapeutic applications.
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New England Biolabs supplies a reaction buffer with all of its enzymes. At a 1X concentration this reaction buffer assures optimal activity of T3, T7, Hi-T4 and Salt-T4 DNA Ligases .
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Many cellular processes are regulated by reversible phosphorylation of proteins and approximately 30% of proteins may become phosphorylated during their lifetime Cellular crude extracts contain numerous endogenous enzymes such as phosphatases and proteases which can degrade and modify proteins present in the extract Addition of inhibitors for these enzymes is the optimal approach for maximizing intact protein yield Phosphatase Inhibitor Cocktail 2 inhibits tyrosine protein phosphatases acid phosphatases and alkaline phosphatases Phosphatase Inhibitor Cocktail 2 has been optimized and tested in cell extracts from multiple animal tissues This Phosphatase Inhibitor Cocktail 2 contains Sodium orthovanadate Sodium molybdate Sodium tartrate Imidazole and Sodium Fluoride It is supplied as a ready-to-use solution in ddH2O
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Many cellular processes are regulated by reversible phosphorylation of proteins and approximately 30% of proteins may become phosphorylated during their lifetime Cellular crude extracts contain numerous endogenous enzymes such as phosphatases and proteases which can degrade and modify proteins present in the extract Addition of inhibitors for these enzymes is the optimal approach for maximizing intact protein yield Phosphatase Inhibitor Cocktail 1 inhibits alkaline phosphatase L-isoenzymes and serine/threonine phosphatases such as protein phosphatases 1 and 2A (PP1 and PP2A) It has been optimized and tested in cell extracts from various animal tissues This Phosphatase Inhibitor Cocktail 1 contains Cantharidin Bromotetramisole and Microcystin LR It is supplied as a ready-to-use solution in DMSO
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Numerous cellular processes are regulated by reversible protein phosphorylation with approximately 30% of proteins being phosphorylated during their lifespan Crude cell extracts contain various endogenous enzymes such as phosphatases and proteases which can degrade and alter proteins in the extracts Therefore the optimal method to increase the yield of intact proteins is to add inhibitors targeting these enzymes Phosphatase Inhibitor Cocktail 3 inhibits alkaline phosphatase L-isozymes and serine/threonine protein phosphatases such as protein phosphatase 1 and 2A (PP1 and PP2A) Phosphatase Inhibitor Cocktail 3 has been optimized and tested in cell extracts from various animal tissues Phosphatase Inhibitor Cocktail 3 can replace Phosphatase Inhibitor Cocktail 1 as the two cocktails have equivalent activities Phosphatase Inhibitor Cocktail 3 contains Cantharidin Bromotetramisole and Calyculin A This Phosphatase Inhibitor Cocktail is supplied as a ready-to-use solution in DMSO
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More