General Clinical Chemistry Analyzers and Accessories
Abcam Adaphostin, 25MG
MW 393.5 Da, Purity >=98%. Adaphostin is a p210bcr/abl tyrosine kinase inhibitor (IC50 = 14 μM) that displays anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 and other cancer cell lines. Adaphostin is a potent inducer of myeloid cell death.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SCR7 pyrazine, NHEJ inhibitor, 5MG
MW 332.4 Da, Purity >98%. Small molecule nonhomologous end-joining (NHEJ) inhibitor. SCR7 analog. Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SCR7 pyrazine, NHEJ inhibitor, 25MG
MW 332.4 Da, Purity >98%. Small molecule nonhomologous end-joining (NHEJ) inhibitor. SCR7 analog. Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Dinaciclib, cyclin-dependent kinase (CDK) inhibitor, 5MG
MW 396.5 Da, Purity >98%. Novel, potent, selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 (IC₅₀ values are 3, 1, 1 and 4 nM respectively). Potent DNA replication inhibitor that blocks thymidine incorporation in A2780 ovarian cancer cells (IC₅₀ = 4 nM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam GSK-690693 hydrochloride, ATP-competitive pan-Akt kinase inhibitor, 5MG
MW 425.5 Da, Purity >99%. Novel ATP-competitive pan-Akt kinase inhibitor (IC₅₀ values are 2, 13 and 9 nM for Akt1, 2 and 3 respectively). Also exhibits some inhibition of AMPK, PKA and PAK and PKC isoforms (IC₅₀ < 100 nM). Displays antiproliferative and apoptotic effects in tumor cell lines.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Elvitegravir, quinolone HIV integrase inhibitor, 50MG
MW 447.9 Da, Purity >99%. Elvitegravir is an inhibitor of HIV integrase. It inhibits HIV integrase from HIV 1 IIIB (IC₅₀ = 0.7 nM), HIV 2 EHO (IC₅₀ = 2.8 nM) and HIV-2 ROD (IC₅₀ = 1.1 nM) in cell free assays. Elvitegravir blocks integration of HIV cDNA via inhibition of DNA strand transfer. Active against a range of HIV sub-types and against mulit-drug resistant clinical isolates. Potent (IC₅₀ range = 0.21 - 1.15 nM) HIV antiviral activity in various cell-based assays.
The product is subject to the following: Abcam Restricted Use Statement
Abcam E7820, 5MG
MW 336.4 Da, Purity >=98%. A small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Cyflufenamid
Chemical. CAS 180409-60-3. Formula C20H17F5N2O2. MW 412.36. Synthetic Amidoxime fungicide used in agroculture. Active against powdery mildew of various crops in pre and post infection treatment. Has a long lasting translaminar and vapor phase activity. The mode of action is not know and it is considered different from that of other existing fungicides. It has favorable toxicological, ecotoxicological and environmental profiles. Compound can be used as analytical reference material.
Abcam 4'-hydro x yazobenzene-2-carbo x ylic acid (HABA), 5G
MW 242.23 Da. An endogenous metabolite. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4'-hydro x yazobenzene-2-carbo x ylic acid (HABA), 1G
MW 242.23 Da. An endogenous metabolite. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CHIR-124, 5MG
MW 419.9 Da, Purity >98%. Novel and potent Chk1 inhibitor (IC₅₀ = 0.3 nM), 2,000-fold more potent than Chk2 (IC₅₀ = 0.7 μM). Also, potently targets other kinases such as FLT3 (IC₅₀ = 5.8 nM), PDGFR (IC₅₀ = 6.6 nM), GSK-3 (IC₅₀ = 23.3 nM) and Fyn (IC₅₀ = 98.8 nM) .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Calcein Blue AM acetate, 1MG
MW 465.4 Da, Purity >95%. Blue fluorescent cell viability probe which won't overlap with green fluorescence from other probes. Penetrates live cell membranes and is virtually non-fluorescent. Upon ubiquitous esterase enzyme activity it produces a bright blue fluorescent that is trapped in live cells - convenient for measurement by epifluorescence light microscopy or flow cytometry. Useful to measure the total number of live versus dead cells - dye leaks out quickly due to the compromised membrane in dead cells resulting in no staining.
The product is subject to the following: Abcam Restricted Use Statement