General Clinical Chemistry Analyzers and Accessories
Abcam FC 131, C x CR4 activation inhibitor, 10MG
MW 729.8 Da, Purity >95%. FC 131, CXCR4 activation inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Alkali Scientific 5mL False Bottom Analyzer Tubes with Threads, 16×97mm, Polypropylene (PP), Amber, 5000/Case
These 5mL False Bottom Analyzer Tubes (16×97mm) with Threads are designed for use in high volume chemistry and diagnostic analyzers. They are compatible with popular analyzers from Hitachi, Olympus, Corning, Ortho, Kodak, Beckman, IA, Tosoh, Vitros and more. Manufactured from high grade polypropylene (PP), these tubes offer excellent chemical resistance and can be safely autoclaved at 121 °C. With a conical false bottom for reduced dead volume and accurate sample retrieval, these tubes are ideal for serum collection, sample transport, or storage. Available in natural or amber options to protect light sensitive samples, they are self standing and designed to fit most universal analyzer racks, including AU 5000 systems. Features: 5mL nominal capacity, 16×97 mm Compatible with Hitachi, Olympus, Corning, Ortho, Beckman, Vitros, Tosoh, and other analyzers Made of chemical resistant polypropylene; autoclavable at 121 °C Available in natural or amber PP for light sensitific.
Abcam Ticagrelor, P2Y12 receptor antagonist, 10MG
MW 522.6 Da, Purity >98%. Reversible antagonist of the platelet purinergic P2Y12 receptor, the main receptor responsible for ADP-induced platelet aggregation. Changes the conformation of the P2Y12 receptor, resulting in reversible, concentration dependent inhibition of the receptor.
The product is subject to the following: Abcam Restricted Use Statement
Abcam HDM-201 (Siremadlin), 1MG
MW 555.4 Da, Purity >=98%. Potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value (0.21 nM). It activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CUR 61414, Hedgehog signaling pathway antagonist, 5MG
MW 550.7 Da, Purity >98%. Novel, cell permeable Hedgehog signaling pathway antagonist (IC₅₀ = 100-200 nM). Selectively binds to smoothened (Smo) (Ki = 44 nM). Blocks the formation of and induces the regression of basaloid lesions in skin punches and shrinks UV-induced basaloid lesions in adult mouse skin. Inhibits proliferation and induces apoptosis in tumor cells without affecting non-tumor cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SGI1776, 50MG
MW 405.4 Da, Purity >99%. Novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM, 50- and 10-fold selective versus Pim2 and Pim3. Preliminary results from studies treating prostate cancer cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GLPG-1690, 25MG
MW 588.7 Da, Purity >=98%. Selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Vistusertib (AZD2014), 5MG
MW 462.5 Da, Purity >98%. Novel potent and selective mammalian rapamycin (mTOR) inhibitor (IC₅₀ = 2.8 nM). Highly selective against multiple PI3K isoforms. Also targets P-Akt (IC₅₀ = 80 nM) and pS6 (IC₅₀ = 200 nM). An oral inhibitor with potential anti-neoplastic activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ABT-199 (Venetocla x ), Bcl-2 inhibitor., 5MG
MW 868.4 Da, Purity >98%. Potent, selective Bcl-2 inhibitor (Ki <0.01 nM) that inhibits the growth of Bcl-2–dependent tumors while sparing platelets. Bcl-2–specific BH3 mimetic. Promising agent in the treatment of chronic lymphocytic leukaemic and estrogen receptor-positive breast cancer.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Cyclotrisiloxanol pentamethyl
Chemical. CAS 106916-50-1. Formula C5H16O4Si3. MW 224.43. Organosilicon compounds are organometallic compounds containing carbon-silicon bonds. Organosilicon compounds are widely encountered in commercial products. Most common are antifoamers, caulks sealant, adhesives, and coatings made from silicones. Other important uses include agricultural and plant control adjuvants commonly used in conjunction with herbicides and fungicides. Several organosilicon compounds have been investigated as pharmaceuticals.
Abcam Elvitegravir, quinolone HIV integrase inhibitor, 50MG
MW 447.9 Da, Purity >99%. Elvitegravir is an inhibitor of HIV integrase. It inhibits HIV integrase from HIV 1 IIIB (IC₅₀ = 0.7 nM), HIV 2 EHO (IC₅₀ = 2.8 nM) and HIV-2 ROD (IC₅₀ = 1.1 nM) in cell free assays. Elvitegravir blocks integration of HIV cDNA via inhibition of DNA strand transfer. Active against a range of HIV sub-types and against mulit-drug resistant clinical isolates. Potent (IC₅₀ range = 0.21 - 1.15 nM) HIV antiviral activity in various cell-based assays.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Coumaphos
Chemical. CAS 56-72-4. Formula C14H16ClO5PS. MW 362.77. Synthetic. An organophosphate pesticide. Acetylcholinesterase AChE inhibitor in the nervous system with subsequent accumulation of toxic levels of acetylcholine ACh. Selective insecticide used for control of a wide variety of livestock insects, including cattle grubs, screw-worms, lice, scabies, flies and ticks. Also used against ectoparasites, which are insects that live on the outside of host animals such as sheep, goats, horses, pigs and poultry. Not used on agricultural or residential plants.