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Cytochalasin D is a cell permeable fungal toxin that binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits.
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Irreversibly inhibits activity of Caspase-1 and -4. Z-Tyr-Val-Ala-Asp(OMe)-Fluoromethylketone, MP Biomedicals peptides are potent, cell permeable, irreversible inhibitors that are used for both in vitro and in vivo applications.
The Z-VAD(OMe)-FMK inhibitor synthesized using proprietary technology is cell permeable and irreversibly binds to activated Caspases to block apoptosis.